Reviewed, UniProtKB/Swiss-Prot Q58539 (RNP3_METJA)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 3
      Short name=RNase P component 3
    EC=3.1.26.5

Gene names

Name:	rnp3
Ordered Locus Names:	MJ1139

Organism

Methanocaldococcus jannaschii (Methanococcus jannaschii) [Complete proteome] [HAMAP]

Taxonomic identifier

2190 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00756
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00756
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential. HAMAP MF_00756
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 232	232	Ribonuclease P protein component 3 HAMAP MF_00756		PRO_0000140039

Sequences

	Sequence		Length	Mass (Da)
	Q58539-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 5490A2447A7E897B	FASTA	232	27,346
	10 20 30 40 50 60 MRIDINRIEK EEDIKLLKEL KWNGFVFYQY DDEFSKDRYE EVKAIAESYK LKVYSGVKIK 70 80 90 100 110 120 TESSKQLRDK VKKFRNKCHI ILIEGGVLKI NRAAVELHDV DILSTPELGR KDSGIDHVLA 130 140 150 160 170 180 RLASNHRVAI ELNFKTLLNK DGYERARTLL FFRNNLKLAK KFDVPVVIST DAENKYQIKN 190 200 210 220 230 PYDLRAFLNT LVEPLYAKKI METAYKICDF RDYLMRDNVV RYGVEIIKEE KE

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB99146.1.
PIR	B64442.
RefSeq	NP_248131.1.
3D structure databases
SMR	Q58539. Positions 7-199.
ModBase	Search...
Genome annotation databases
GeneID	1452035.
GenomeReviews	Gene locus MJ1139 in contig L77117_GR.
KEGG	mja:MJ1139.
NMPDR	fig|243232.1.peg.1168.
TIGR	MJ1139.
Phylogenomic databases
HOGENOM	HBG541018.
OMA	IYGIKAP.
Enzyme and pathway databases
BRENDA	3.1.26.5. 256362.
Family and domain databases
HAMAP	MF_00756. RNase_P_3. [Tree]
InterPro	IPR016195. Pol/histidinol_Pase-like. IPR002738. RNase_P_p30. [Graphical view]
Pfam	PF01876. RNase_P_p30. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNP3_METJA

Accession

Primary (citable) accession number: Q58539

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2003
Last sequence update:	November 1, 1996
Last modified:	January 19, 2010
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)