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Q58473

- RIO2_METJA

UniProt

Q58473 - RIO2_METJA

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Protein

RIO-type serine/threonine-protein kinase Rio2

Gene

rio2

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Cofactori

Magnesium.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi76 – 761Magnesium 1By similarity
Binding sitei93 – 931ATPPROSITE-ProRule annotation
Active sitei202 – 2021Proton acceptorPROSITE-ProRule annotation
Metal bindingi207 – 2071Magnesium 2By similarity
Metal bindingi220 – 2201Magnesium 1By similarity
Metal bindingi220 – 2201Magnesium 2By similarity
Binding sitei220 – 2201ATPPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi72 – 776ATPPROSITE-ProRule annotation
Nucleotide bindingi158 – 1647ATPPROSITE-ProRule annotation
Nucleotide bindingi206 – 2072ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RIO-type serine/threonine-protein kinase Rio2 (EC:2.7.11.1)
Gene namesi
Name:rio2
Ordered Locus Names:MJ1073
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 270270RIO-type serine/threonine-protein kinase Rio2PRO_0000213535Add
BLAST

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi243232.MJ1073.

Structurei

3D structure databases

ProteinModelPortaliQ58473.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini65 – 270206Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0478.
InParanoidiQ58473.
KOiK07179.
OMAiHREGYTN.
PhylomeDBiQ58473.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR018934. RIO-like_kinase.
IPR015285. RIO2_kinase_winged_hlx_N.
IPR000687. RIO_kinase.
IPR018935. RIO_kinase_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01163. RIO1. 1 hit.
PF09202. Rio2_N. 1 hit.
[Graphical view]
SMARTiSM00090. RIO. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS01245. RIO1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q58473-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRHHEWVPLD EIVRKAKMPE KDVLYRLKRL NKFGFVVRST YGYAVSMGGY
60 70 80 90 100
DALAINAFVK KGILKAIGNK LGVGKEGDVY TVLLSDGREA VLKFHKHGRT
110 120 130 140 150
CFTRGKRYRG YLADKHHISW LYVSRLTAER EFEILNELFP IVKVPEPIEW
160 170 180 190 200
NRHAIIMGKV VGEELKRLDL SEFMSKEEIK DLFWKIIEEV KKAYEIGYIH
210 220 230 240 250
GDLSEFNILL DENGDFVIID WPQAVPKYHP DAEFYLKRDI WNVIRYFKKY
260 270
KIDKEDEKID VDKIFEYITK
Length:270
Mass (Da):31,881
Last modified:November 1, 1996 - v1
Checksum:i837BCE317A8A5CDF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB99073.1.
PIRiH64433.
RefSeqiNP_248066.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB99073; AAB99073; MJ_1073.
GeneIDi1451969.
KEGGimja:MJ_1073.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB99073.1 .
PIRi H64433.
RefSeqi NP_248066.1. NC_000909.1.

3D structure databases

ProteinModelPortali Q58473.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243232.MJ1073.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB99073 ; AAB99073 ; MJ_1073 .
GeneIDi 1451969.
KEGGi mja:MJ_1073.

Phylogenomic databases

eggNOGi COG0478.
InParanoidi Q58473.
KOi K07179.
OMAi HREGYTN.
PhylomeDBi Q58473.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR018934. RIO-like_kinase.
IPR015285. RIO2_kinase_winged_hlx_N.
IPR000687. RIO_kinase.
IPR018935. RIO_kinase_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF01163. RIO1. 1 hit.
PF09202. Rio2_N. 1 hit.
[Graphical view ]
SMARTi SM00090. RIO. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS01245. RIO1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Entry informationi

Entry nameiRIO2_METJA
AccessioniPrimary (citable) accession number: Q58473
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3