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Q58473

- RIO2_METJA

UniProt

Q58473 - RIO2_METJA

Protein

RIO-type serine/threonine-protein kinase Rio2

Gene

rio2

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Cofactori

    Magnesium.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi76 – 761Magnesium 1By similarity
    Binding sitei93 – 931ATPPROSITE-ProRule annotation
    Active sitei202 – 2021Proton acceptorPROSITE-ProRule annotation
    Metal bindingi207 – 2071Magnesium 2By similarity
    Metal bindingi220 – 2201Magnesium 1By similarity
    Metal bindingi220 – 2201Magnesium 2By similarity
    Binding sitei220 – 2201ATPPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi72 – 776ATPPROSITE-ProRule annotation
    Nucleotide bindingi158 – 1647ATPPROSITE-ProRule annotation
    Nucleotide bindingi206 – 2072ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RIO-type serine/threonine-protein kinase Rio2 (EC:2.7.11.1)
    Gene namesi
    Name:rio2
    Ordered Locus Names:MJ1073
    OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
    Taxonomic identifieri243232 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
    ProteomesiUP000000805: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 270270RIO-type serine/threonine-protein kinase Rio2PRO_0000213535Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Protein-protein interaction databases

    STRINGi243232.MJ1073.

    Structurei

    3D structure databases

    ProteinModelPortaliQ58473.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini65 – 270206Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0478.
    KOiK07179.
    OMAiHREGYTN.
    PhylomeDBiQ58473.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR018934. RIO-like_kinase.
    IPR015285. RIO2_kinase_winged_hlx_N.
    IPR000687. RIO_kinase.
    IPR018935. RIO_kinase_CS.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF01163. RIO1. 1 hit.
    PF09202. Rio2_N. 1 hit.
    [Graphical view]
    SMARTiSM00090. RIO. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS01245. RIO1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q58473-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRHHEWVPLD EIVRKAKMPE KDVLYRLKRL NKFGFVVRST YGYAVSMGGY    50
    DALAINAFVK KGILKAIGNK LGVGKEGDVY TVLLSDGREA VLKFHKHGRT 100
    CFTRGKRYRG YLADKHHISW LYVSRLTAER EFEILNELFP IVKVPEPIEW 150
    NRHAIIMGKV VGEELKRLDL SEFMSKEEIK DLFWKIIEEV KKAYEIGYIH 200
    GDLSEFNILL DENGDFVIID WPQAVPKYHP DAEFYLKRDI WNVIRYFKKY 250
    KIDKEDEKID VDKIFEYITK 270
    Length:270
    Mass (Da):31,881
    Last modified:November 1, 1996 - v1
    Checksum:i837BCE317A8A5CDF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB99073.1.
    PIRiH64433.
    RefSeqiNP_248066.1. NC_000909.1.
    WP_010870585.1. NC_000909.1.

    Genome annotation databases

    EnsemblBacteriaiAAB99073; AAB99073; MJ_1073.
    GeneIDi1451969.
    KEGGimja:MJ_1073.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB99073.1 .
    PIRi H64433.
    RefSeqi NP_248066.1. NC_000909.1.
    WP_010870585.1. NC_000909.1.

    3D structure databases

    ProteinModelPortali Q58473.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243232.MJ1073.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB99073 ; AAB99073 ; MJ_1073 .
    GeneIDi 1451969.
    KEGGi mja:MJ_1073.

    Phylogenomic databases

    eggNOGi COG0478.
    KOi K07179.
    OMAi HREGYTN.
    PhylomeDBi Q58473.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR018934. RIO-like_kinase.
    IPR015285. RIO2_kinase_winged_hlx_N.
    IPR000687. RIO_kinase.
    IPR018935. RIO_kinase_CS.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF01163. RIO1. 1 hit.
    PF09202. Rio2_N. 1 hit.
    [Graphical view ]
    SMARTi SM00090. RIO. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS01245. RIO1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

    Entry informationi

    Entry nameiRIO2_METJA
    AccessioniPrimary (citable) accession number: Q58473
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 14, 2003
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Methanococcus jannaschii
      Methanococcus jannaschii: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3