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Q58272 (IDI2_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isopentenyl-diphosphate delta-isomerase
Short name=IPP isomerase
EC=5.3.3.2
Alternative name(s):
Isopentenyl pyrophosphate isomerase
Gene names
Name:fni
Ordered Locus Names:MJ0862
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) By similarity. HAMAP MF_00354

Catalytic activity

Isopentenyl diphosphate = dimethylallyl diphosphate. HAMAP MF_00354

Cofactor

FMN By similarity. HAMAP MF_00354

NADPH By similarity. HAMAP MF_00354

Subcellular location

Cytoplasm By similarity HAMAP MF_00354.

Sequence similarities

Belongs to the IPP isomerase type 2 family.

Ontologies

Keywords
   Biological processIsoprene biosynthesis
   Cellular componentCytoplasm
   LigandFMN
Flavoprotein
NADP
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processisoprenoid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionFMN binding

Inferred from electronic annotation. Source: InterPro

isopentenyl-diphosphate delta-isomerase activity

Inferred from electronic annotation. Source: EC

oxidoreductase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 359359Isopentenyl-diphosphate delta-isomerase HAMAP MF_00354
PRO_0000134444

Sequences

Sequence LengthMass (Da)Tools
Q58272 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 46BDD320262772EA

FASTA35939,875
        10         20         30         40         50         60 
MVNNRNEIEV RKLEHIFLCS YCNVEYEKTT LLEDIELIHK GTCGINFNDI ETEIELFGKK 

        70         80         90        100        110        120 
LSAPIIVSGM TGGHSKAKEI NKNIAKAVEE LGLGMGVGSQ RAAIVNDELI DTYSIVRDYT 

       130        140        150        160        170        180 
NNLVIGNLGA VNFIVDDWDE EIIDKAIEMI DADAIAIHFN PLQEIIQPEG DLNFKNLYKL 

       190        200        210        220        230        240 
KEIISNYKKS YKNIPFIAKQ VGEGFSKEDA LILKDIGFDA IDVQGSGGTS WAKVEIYRVK 

       250        260        270        280        290        300 
EEEIKRLAEK FANWGIPTAA SIFEVKSVYD GIVIGSGGIR GGLDIAKCIA IGCDCCSVAL 

       310        320        330        340        350 
PILKASLKGW EEVVKVLESY IKELKIAMFL VGAENIEELK KTSYIVKGTL KEWISQRLK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L77117 Genomic DNA. Translation: AAB98867.1.
PIRF64407.
RefSeqNP_247857.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ58272.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1451751.
GenomeReviewsGene locus MJ0862 in contig L77117_GR.
KEGGmja:MJ_0862.
NMPDRfig|243232.1.peg.894.
TIGRMJ0862.

Phylogenomic databases

HOGENOMHBG354479.
OMAGSQRAAI.
ProtClustDBPRK05437.

Enzyme and pathway databases

BioCycMJAN243232:MJ_0862-MONOMER.

Family and domain databases

HAMAPMF_00354. Idi_2.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR000262. FMN-dep_DH.
IPR011179. IPdP_isomerase.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01823.
PANTHERPTHR10578:SF3. IPdP_isomerase. 1 hit.
PfamPF01070. FMN_dh. 2 hits.
[Graphical view]
PIRSFPIRSF003314. IPP_isomerase. 1 hit.
TIGRFAMsTIGR02151. IPP_isom_2. 1 hit.
ProtoNetSearch...

Entry information

Entry nameIDI2_METJA
AccessionPrimary (citable) accession number: Q58272
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 16, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names

SIMILARITY comments

Index of protein domains and families

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