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Q58257 (MTRE_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tetrahydromethanopterin S-methyltransferase subunit E
EC=2.1.1.86
Alternative name(s):
N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E
Gene names
Name:mtrE
Ordered Locus Names:MJ0847
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length303 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step By similarity. HAMAP MF_01098

Catalytic activity

5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate = 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate. HAMAP MF_01098

Pathway

One-carbon metabolism; methanogenesis from CO(2); methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 2/2. HAMAP MF_01098

Subunit structure

The complex is composed of 8 subunits; mtrA, mtrB, mtrC, mtrD, mtrE, mtrF, mtrG and mtrH By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein Potential HAMAP MF_01098.

Sequence similarities

Belongs to the mtrE family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 303303Tetrahydromethanopterin S-methyltransferase subunit E HAMAP MF_01098
PRO_0000147539

Regions

Transmembrane3 – 2321Helical; Potential
Transmembrane63 – 8321Helical; Potential
Transmembrane86 – 10621Helical; Potential
Transmembrane133 – 15321Helical; Potential
Transmembrane157 – 17721Helical; Potential
Transmembrane226 – 24621Helical; Potential
Transmembrane266 – 28621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q58257 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 46BA1BBD80FECCE2

FASTA30331,635
        10         20         30         40         50         60 
MDATLIALGA LALSGALATV AGCAEDLESD VGSQSNPNSQ VQLAPQMGNI HRYFNKAISG 

        70         80         90        100        110        120 
EPVSYGLYVA VAGTVAYAIM QMGLNPILAL ILGAGVAAFV HGAYAISAYL GRIVGQSKNF 

       130        140        150        160        170        180 
GQPVYWDVVM SHLGPIVGHG FIAVFCMVLM AYLANTILGN PFPLPLIALI FGITVGAIGS 

       190        200        210        220        230        240 
STGDVHYGAE REYQKYPFGG GVPVANHGDI DIKAEYGLRN GMDSSYFCSR LGGVLTGLCF 

       250        260        270        280        290        300 
GLIVFLDGWR GVLGDILKGG QGGSVITASI ISIVIGLIIV AILAIINRKV EVFARNKYGP 


YTK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L77117 Genomic DNA. Translation: AAB98852.1.
PIRG64405.
RefSeqNP_247841.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ58257.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1451735.
GenomeReviewsGene locus MJ0847 in contig L77117_GR.
KEGGmja:MJ_0847.
NMPDRfig|243232.1.peg.878.
TIGRMJ0847.

Phylogenomic databases

HOGENOMHBG539646.
OMASNPNSQV.
ProtClustDBPRK00972.

Enzyme and pathway databases

BioCycMJAN243232:MJ_0847-MONOMER.

Family and domain databases

HAMAPMF_01098. MtrE.
[Tree]
InterProIPR005780. MeTrfase_E.
[Graphical view]
KOK00581.
PfamPF04206. MtrE. 1 hit.
[Graphical view]
PIRSFPIRSF016509. MtrE. 1 hit.
TIGRFAMsTIGR01113. MtrE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMTRE_METJA
AccessionPrimary (citable) accession number: Q58257
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 16, 2011
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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