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Q58235

- FKBP2_METJA

UniProt

Q58235 - FKBP2_METJA

Protein

Putative FKBP-type peptidyl-prolyl cis-trans isomerase MJ0825

Gene

MJ0825

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 2 (15 Dec 1998)
      Previous versions | rss
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    Functioni

    PPIases accelerate the folding of proteins.

    Catalytic activityi

    Peptidylproline (omega=180) = peptidylproline (omega=0).

    GO - Molecular functioni

    1. peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-KW

    GO - Biological processi

    1. protein folding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Isomerase, Rotamase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative FKBP-type peptidyl-prolyl cis-trans isomerase MJ0825 (EC:5.2.1.8)
    Short name:
    PPIase
    Alternative name(s):
    Rotamase
    Gene namesi
    Ordered Locus Names:MJ0825
    OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
    Taxonomic identifieri243232 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
    ProteomesiUP000000805: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 231231Putative FKBP-type peptidyl-prolyl cis-trans isomerase MJ0825PRO_0000075377Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243232.MJ0825.

    Structurei

    Secondary structure

    1
    231
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi7 – 1610
    Beta strandi19 – 246
    Helixi26 – 316
    Beta strandi44 – 474
    Beta strandi50 – 534
    Helixi55 – 639
    Beta strandi69 – 746
    Helixi76 – 783
    Helixi85 – 873
    Beta strandi88 – 925
    Helixi93 – 986
    Beta strandi108 – 1114
    Beta strandi114 – 1229
    Beta strandi125 – 1295
    Turni133 – 1364
    Beta strandi139 – 14911
    Helixi152 – 16312
    Beta strandi171 – 1755
    Beta strandi178 – 1825
    Helixi187 – 1893
    Helixi193 – 20715
    Beta strandi213 – 2219

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3PR9X-ray1.95A1-150[»]
    3PRAX-ray2.40A/B1-150[»]
    3PRBX-ray2.20A/B1-231[»]
    3PRDX-ray3.30A1-231[»]
    ProteinModelPortaliQ58235.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ58235.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini5 – 9288PPIase FKBP-typePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the FKBP-type PPIase family.Curated
    Contains 1 PPIase FKBP-type domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG1047.
    KOiK03775.
    OMAiKMAIANE.
    PhylomeDBiQ58235.

    Family and domain databases

    InterProiIPR023566. PPIase_FKBP.
    IPR001179. PPIase_FKBP_dom.
    [Graphical view]
    PANTHERiPTHR10516. PTHR10516. 1 hit.
    PfamiPF00254. FKBP_C. 1 hit.
    [Graphical view]
    PROSITEiPS50059. FKBP_PPIASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q58235-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVEKGKMVKI SYDGYVDGKL FDTTNEELAK KEGIYNPAMI YGPVAIFAGE    50
    GQVLPGLDEA ILEMDVGEER EVVLPPEKAF GKRDPSKIKL IPLSEFTKRG 100
    IKPIKGLTIT IDGIPGKIVS INSGRVLVDF NHELAGKEVK YRIKIEEVVD 150
    DKKNIVKEIV KMYVPRLSDV KVTIRNGTVK IELPEFAPFI PNIQTAKMAI 200
    ANEILKRLED AEKVSFVETF ERKKETKEEN K 231
    Length:231
    Mass (Da):25,947
    Last modified:December 15, 1998 - v2
    Checksum:iABD9AD1DB1B6C420
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98824.1.
    RefSeqiNP_247816.1. NC_000909.1.
    WP_010870336.1. NC_000909.1.

    Genome annotation databases

    EnsemblBacteriaiAAB98824; AAB98824; MJ_0825.
    GeneIDi1451708.
    KEGGimja:MJ_0825.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98824.1 .
    RefSeqi NP_247816.1. NC_000909.1.
    WP_010870336.1. NC_000909.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3PR9 X-ray 1.95 A 1-150 [» ]
    3PRA X-ray 2.40 A/B 1-150 [» ]
    3PRB X-ray 2.20 A/B 1-231 [» ]
    3PRD X-ray 3.30 A 1-231 [» ]
    ProteinModelPortali Q58235.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243232.MJ0825.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB98824 ; AAB98824 ; MJ_0825 .
    GeneIDi 1451708.
    KEGGi mja:MJ_0825.

    Phylogenomic databases

    eggNOGi COG1047.
    KOi K03775.
    OMAi KMAIANE.
    PhylomeDBi Q58235.

    Miscellaneous databases

    EvolutionaryTracei Q58235.

    Family and domain databases

    InterProi IPR023566. PPIase_FKBP.
    IPR001179. PPIase_FKBP_dom.
    [Graphical view ]
    PANTHERi PTHR10516. PTHR10516. 1 hit.
    Pfami PF00254. FKBP_C. 1 hit.
    [Graphical view ]
    PROSITEi PS50059. FKBP_PPIASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

    Entry informationi

    Entry nameiFKBP2_METJA
    AccessioniPrimary (citable) accession number: Q58235
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: December 15, 1998
    Last modified: October 1, 2014
    This is version 82 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Methanococcus jannaschii
      Methanococcus jannaschii: entries and gene names
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3