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Q58235

- FKBP2_METJA

UniProt

Q58235 - FKBP2_METJA

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Protein

Putative FKBP-type peptidyl-prolyl cis-trans isomerase MJ0825

Gene

MJ0825

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

PPIases accelerate the folding of proteins.

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

GO - Molecular functioni

  1. peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-KW

GO - Biological processi

  1. protein folding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase, Rotamase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative FKBP-type peptidyl-prolyl cis-trans isomerase MJ0825 (EC:5.2.1.8)
Short name:
PPIase
Alternative name(s):
Rotamase
Gene namesi
Ordered Locus Names:MJ0825
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 231231Putative FKBP-type peptidyl-prolyl cis-trans isomerase MJ0825PRO_0000075377Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ0825.

Structurei

Secondary structure

1
231
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi7 – 1610
Beta strandi19 – 246
Helixi26 – 316
Beta strandi44 – 474
Beta strandi50 – 534
Helixi55 – 639
Beta strandi69 – 746
Helixi76 – 783
Helixi85 – 873
Beta strandi88 – 925
Helixi93 – 986
Beta strandi108 – 1114
Beta strandi114 – 1229
Beta strandi125 – 1295
Turni133 – 1364
Beta strandi139 – 14911
Helixi152 – 16312
Beta strandi171 – 1755
Beta strandi178 – 1825
Helixi187 – 1893
Helixi193 – 20715
Beta strandi213 – 2219

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3PR9X-ray1.95A1-150[»]
3PRAX-ray2.40A/B1-150[»]
3PRBX-ray2.20A/B1-231[»]
3PRDX-ray3.30A1-231[»]
ProteinModelPortaliQ58235.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ58235.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 9288PPIase FKBP-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the FKBP-type PPIase family.Curated
Contains 1 PPIase FKBP-type domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG1047.
InParanoidiQ58235.
KOiK03775.
OMAiKMAIANE.
PhylomeDBiQ58235.

Family and domain databases

InterProiIPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
[Graphical view]
PANTHERiPTHR10516. PTHR10516. 1 hit.
PfamiPF00254. FKBP_C. 1 hit.
[Graphical view]
PROSITEiPS50059. FKBP_PPIASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q58235 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVEKGKMVKI SYDGYVDGKL FDTTNEELAK KEGIYNPAMI YGPVAIFAGE
60 70 80 90 100
GQVLPGLDEA ILEMDVGEER EVVLPPEKAF GKRDPSKIKL IPLSEFTKRG
110 120 130 140 150
IKPIKGLTIT IDGIPGKIVS INSGRVLVDF NHELAGKEVK YRIKIEEVVD
160 170 180 190 200
DKKNIVKEIV KMYVPRLSDV KVTIRNGTVK IELPEFAPFI PNIQTAKMAI
210 220 230
ANEILKRLED AEKVSFVETF ERKKETKEEN K
Length:231
Mass (Da):25,947
Last modified:December 15, 1998 - v2
Checksum:iABD9AD1DB1B6C420
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB98824.1.
RefSeqiNP_247816.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98824; AAB98824; MJ_0825.
GeneIDi1451708.
KEGGimja:MJ_0825.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB98824.1 .
RefSeqi NP_247816.1. NC_000909.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3PR9 X-ray 1.95 A 1-150 [» ]
3PRA X-ray 2.40 A/B 1-150 [» ]
3PRB X-ray 2.20 A/B 1-231 [» ]
3PRD X-ray 3.30 A 1-231 [» ]
ProteinModelPortali Q58235.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243232.MJ0825.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB98824 ; AAB98824 ; MJ_0825 .
GeneIDi 1451708.
KEGGi mja:MJ_0825.

Phylogenomic databases

eggNOGi COG1047.
InParanoidi Q58235.
KOi K03775.
OMAi KMAIANE.
PhylomeDBi Q58235.

Miscellaneous databases

EvolutionaryTracei Q58235.

Family and domain databases

InterProi IPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
[Graphical view ]
PANTHERi PTHR10516. PTHR10516. 1 hit.
Pfami PF00254. FKBP_C. 1 hit.
[Graphical view ]
PROSITEi PS50059. FKBP_PPIASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Entry informationi

Entry nameiFKBP2_METJA
AccessioniPrimary (citable) accession number: Q58235
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 15, 1998
Last modified: October 29, 2014
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3