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Protein

Uncharacterized protein MJ0781

Gene

MJ0781

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi308 – 315ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein MJ0781
Cleaved into the following chain:
Gene namesi
Ordered Locus Names:MJ0781
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 26HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000131221 – 404Uncharacterized protein MJ0781, 1st partSequence analysisAdd BLAST404
ChainiPRO_0000013123405 – 572Mja klbA inteinSequence analysisAdd BLAST168
ChainiPRO_0000013124573 – 721Uncharacterized protein MJ0781, 2nd partSequence analysisAdd BLAST149

Post-translational modificationi

This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation.Curated

Keywords - PTMi

Autocatalytic cleavage, Protein splicing

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ_0781.

Structurei

Secondary structure

1721
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi422 – 432Combined sources11
Turni434 – 436Combined sources3
Beta strandi446 – 448Combined sources3
Turni450 – 452Combined sources3
Beta strandi455 – 457Combined sources3
Turni461 – 464Combined sources4
Beta strandi468 – 470Combined sources3
Beta strandi473 – 477Combined sources5
Beta strandi481 – 484Combined sources4
Beta strandi501 – 506Combined sources6
Beta strandi509 – 514Combined sources6
Helixi515 – 517Combined sources3
Beta strandi522 – 527Combined sources6
Beta strandi529 – 536Combined sources8
Beta strandi542 – 545Combined sources4
Beta strandi549 – 553Combined sources5
Turni555 – 557Combined sources3
Beta strandi558 – 564Combined sources7
Beta strandi568 – 571Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2JMZNMR-A398-577[»]
2JNQNMR-A398-577[»]
ProteinModelPortaliQ58191.
SMRiQ58191.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ58191.

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP E family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiarCOG01817. Archaea.
arCOG01819. Archaea.
COG1372. LUCA.
COG4962. LUCA.
InParanoidiQ58191.
KOiK07332.
OMAiTGHDGCS.

Family and domain databases

Gene3Di2.170.16.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR028992. Hedgehog/Intein_dom.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR030934. Intein_C.
IPR006141. Intein_N.
IPR027417. P-loop_NTPase.
IPR001482. T2SS_protein-E.
[Graphical view]
PfamiPF00437. T2SSE. 1 hit.
[Graphical view]
SMARTiSM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
[Graphical view]
SUPFAMiSSF51294. SSF51294. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEiPS50818. INTEIN_C_TER. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q58191-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIKNQLIFV NFYVILIIWW FVMGILDKIQ KKSEKIEKEK KSETVIPSDT
60 70 80 90 100
KLKPIEPHPT INKKATVGND ETILDTYSIK IDEIEMEVVI KREEGYIYYL
110 120 130 140 150
VPEIDKINMS LSKLTKDHLN HIKSQISDLG LIEYDQIREY LTNFSMRYNL
160 170 180 190 200
AIPYIDSLAK FFYLVIGRLG LLEVPLNDDR LEEVMVNGYN VPVFVFHRKH
210 220 230 240 250
QMCETNIVLD RNEVDRIIES IANLVNRPID SRVPMLDAFL PDGSRVNATT
260 270 280 290 300
ADITMNGATL TIRKFSKNPL TVIDLINFGT LDIDTAAFLW QAVEGYFGAK
310 320 330 340 350
PANTLIAGGT GSGKTTLLNV LSLFSMYNER IITIEDTPEL QIPHKHVIKM
360 370 380 390 400
VTRPARPGMP EYEVTMDDLI KNALRMRPDR IFVGEVRGKE AHSLLVAMNT
410 420 430 440 450
GHDGALAYDE PIYLSDGNII NIGEFVDKFF KKYKNSIKKE DNGFGWIDIG
460 470 480 490 500
NENIYIKSFN KLSLIIEDKR ILRVWRKKYS GKLIKITTKN RREITLTHDH
510 520 530 540 550
PVYISKTGEV LEINAEMVKV GDYIYIPKNN TINLDEVIKV ETVDYNGHIY
560 570 580 590 600
DLTVEDNHTY IAGKNEGFAV SNCSGTLHAN SADEAILRLT SPPMNVPKIM
610 620 630 640 650
LTALNFIINQ QRIRRAGKTI RRILGIVEIV KGGGEGHEFA KTTLYEYNGL
660 670 680 690 700
KDSLERRGIC MWEEEVCEIA GITKEELLRD RENRKKVLSY LYKNNIRKLE
710 720
NVSDYIMRYQ VDPEKLLRSI R
Length:721
Mass (Da):82,743
Last modified:November 1, 1996 - v1
Checksum:i13B76CEC7976F0F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98770.1.
PIRiE64397.

Genome annotation databases

EnsemblBacteriaiAAB98770; AAB98770; MJ_0781.
KEGGimja:MJ_0781.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98770.1.
PIRiE64397.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2JMZNMR-A398-577[»]
2JNQNMR-A398-577[»]
ProteinModelPortaliQ58191.
SMRiQ58191.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243232.MJ_0781.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB98770; AAB98770; MJ_0781.
KEGGimja:MJ_0781.

Phylogenomic databases

eggNOGiarCOG01817. Archaea.
arCOG01819. Archaea.
COG1372. LUCA.
COG4962. LUCA.
InParanoidiQ58191.
KOiK07332.
OMAiTGHDGCS.

Miscellaneous databases

EvolutionaryTraceiQ58191.

Family and domain databases

Gene3Di2.170.16.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR028992. Hedgehog/Intein_dom.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR030934. Intein_C.
IPR006141. Intein_N.
IPR027417. P-loop_NTPase.
IPR001482. T2SS_protein-E.
[Graphical view]
PfamiPF00437. T2SSE. 1 hit.
[Graphical view]
SMARTiSM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
[Graphical view]
SUPFAMiSSF51294. SSF51294. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEiPS50818. INTEIN_C_TER. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY781_METJA
AccessioniPrimary (citable) accession number: Q58191
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Intein-containing proteins
    List of intein-containing protein entries
  2. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.