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Q58191

- Y781_METJA

UniProt

Q58191 - Y781_METJA

Protein

Uncharacterized protein MJ0781

Gene

MJ0781

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi308 – 3158ATPSequence Analysis

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. nucleoside-triphosphatase activity Source: InterPro

    GO - Biological processi

    1. intein-mediated protein splicing Source: InterPro
    2. transport Source: InterPro

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein MJ0781
    Cleaved into the following chain:
    Gene namesi
    Ordered Locus Names:MJ0781
    OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
    Taxonomic identifieri243232 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
    ProteomesiUP000000805: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 404404Uncharacterized protein MJ0781, 1st partSequence AnalysisPRO_0000013122Add
    BLAST
    Chaini405 – 572168Mja klbA inteinSequence AnalysisPRO_0000013123Add
    BLAST
    Chaini573 – 721149Uncharacterized protein MJ0781, 2nd partSequence AnalysisPRO_0000013124Add
    BLAST

    Post-translational modificationi

    This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation.Curated

    Keywords - PTMi

    Autocatalytic cleavage, Protein splicing

    Interactioni

    Protein-protein interaction databases

    STRINGi243232.MJ0781.

    Structurei

    Secondary structure

    1
    721
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi422 – 43211
    Turni434 – 4363
    Beta strandi446 – 4483
    Turni450 – 4523
    Beta strandi455 – 4573
    Turni461 – 4644
    Beta strandi468 – 4703
    Beta strandi473 – 4775
    Beta strandi481 – 4844
    Beta strandi501 – 5066
    Beta strandi509 – 5146
    Helixi515 – 5173
    Beta strandi522 – 5276
    Beta strandi529 – 5368
    Beta strandi542 – 5454
    Beta strandi549 – 5535
    Turni555 – 5573
    Beta strandi558 – 5647
    Beta strandi568 – 5714

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2JMZNMR-A398-577[»]
    2JNQNMR-A398-577[»]
    ProteinModelPortaliQ58191.
    SMRiQ58191. Positions 398-577.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ58191.

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei6 – 2621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GSP E family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1372.
    KOiK07332.
    OMAiTGHDGCS.

    Family and domain databases

    Gene3Di2.170.16.10. 1 hit.
    3.40.50.300. 2 hits.
    InterProiIPR003593. AAA+_ATPase.
    IPR028992. Hedgehog/Intein_dom.
    IPR003586. Hint_dom_C.
    IPR003587. Hint_dom_N.
    IPR006141. Intein_splice_site.
    IPR027417. P-loop_NTPase.
    IPR001482. T2SS_protein-E.
    [Graphical view]
    PfamiPF00437. T2SE. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    SM00305. HintC. 1 hit.
    SM00306. HintN. 1 hit.
    [Graphical view]
    SUPFAMiSSF51294. SSF51294. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR01443. intein_Cterm. 1 hit.
    TIGR01445. intein_Nterm. 1 hit.
    PROSITEiPS50818. INTEIN_C_TER. 1 hit.
    PS50817. INTEIN_N_TER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q58191-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIIKNQLIFV NFYVILIIWW FVMGILDKIQ KKSEKIEKEK KSETVIPSDT    50
    KLKPIEPHPT INKKATVGND ETILDTYSIK IDEIEMEVVI KREEGYIYYL 100
    VPEIDKINMS LSKLTKDHLN HIKSQISDLG LIEYDQIREY LTNFSMRYNL 150
    AIPYIDSLAK FFYLVIGRLG LLEVPLNDDR LEEVMVNGYN VPVFVFHRKH 200
    QMCETNIVLD RNEVDRIIES IANLVNRPID SRVPMLDAFL PDGSRVNATT 250
    ADITMNGATL TIRKFSKNPL TVIDLINFGT LDIDTAAFLW QAVEGYFGAK 300
    PANTLIAGGT GSGKTTLLNV LSLFSMYNER IITIEDTPEL QIPHKHVIKM 350
    VTRPARPGMP EYEVTMDDLI KNALRMRPDR IFVGEVRGKE AHSLLVAMNT 400
    GHDGALAYDE PIYLSDGNII NIGEFVDKFF KKYKNSIKKE DNGFGWIDIG 450
    NENIYIKSFN KLSLIIEDKR ILRVWRKKYS GKLIKITTKN RREITLTHDH 500
    PVYISKTGEV LEINAEMVKV GDYIYIPKNN TINLDEVIKV ETVDYNGHIY 550
    DLTVEDNHTY IAGKNEGFAV SNCSGTLHAN SADEAILRLT SPPMNVPKIM 600
    LTALNFIINQ QRIRRAGKTI RRILGIVEIV KGGGEGHEFA KTTLYEYNGL 650
    KDSLERRGIC MWEEEVCEIA GITKEELLRD RENRKKVLSY LYKNNIRKLE 700
    NVSDYIMRYQ VDPEKLLRSI R 721
    Length:721
    Mass (Da):82,743
    Last modified:November 1, 1996 - v1
    Checksum:i13B76CEC7976F0F3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98770.1.
    PIRiE64397.
    RefSeqiNP_247766.1. NC_000909.1.
    WP_010870286.1. NC_000909.1.

    Genome annotation databases

    EnsemblBacteriaiAAB98770; AAB98770; MJ_0781.
    GeneIDi1451658.
    KEGGimja:MJ_0781.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98770.1 .
    PIRi E64397.
    RefSeqi NP_247766.1. NC_000909.1.
    WP_010870286.1. NC_000909.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2JMZ NMR - A 398-577 [» ]
    2JNQ NMR - A 398-577 [» ]
    ProteinModelPortali Q58191.
    SMRi Q58191. Positions 398-577.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243232.MJ0781.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB98770 ; AAB98770 ; MJ_0781 .
    GeneIDi 1451658.
    KEGGi mja:MJ_0781.

    Phylogenomic databases

    eggNOGi COG1372.
    KOi K07332.
    OMAi TGHDGCS.

    Miscellaneous databases

    EvolutionaryTracei Q58191.

    Family and domain databases

    Gene3Di 2.170.16.10. 1 hit.
    3.40.50.300. 2 hits.
    InterProi IPR003593. AAA+_ATPase.
    IPR028992. Hedgehog/Intein_dom.
    IPR003586. Hint_dom_C.
    IPR003587. Hint_dom_N.
    IPR006141. Intein_splice_site.
    IPR027417. P-loop_NTPase.
    IPR001482. T2SS_protein-E.
    [Graphical view ]
    Pfami PF00437. T2SE. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    SM00305. HintC. 1 hit.
    SM00306. HintN. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51294. SSF51294. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR01443. intein_Cterm. 1 hit.
    TIGR01445. intein_Nterm. 1 hit.
    PROSITEi PS50818. INTEIN_C_TER. 1 hit.
    PS50817. INTEIN_N_TER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

    Entry informationi

    Entry nameiY781_METJA
    AccessioniPrimary (citable) accession number: Q58191
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 102 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Intein-containing proteins
      List of intein-containing protein entries
    2. Methanococcus jannaschii
      Methanococcus jannaschii: entries and gene names
    3. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3