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Protein

Uncharacterized protein MJ0781

Gene

MJ0781

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi308 – 3158ATPSequence Analysis

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. intein-mediated protein splicing Source: InterPro
  2. transport Source: InterPro
Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein MJ0781
Cleaved into the following chain:
Gene namesi
Ordered Locus Names:MJ0781
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2621HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 404404Uncharacterized protein MJ0781, 1st partSequence AnalysisPRO_0000013122Add
BLAST
Chaini405 – 572168Mja klbA inteinSequence AnalysisPRO_0000013123Add
BLAST
Chaini573 – 721149Uncharacterized protein MJ0781, 2nd partSequence AnalysisPRO_0000013124Add
BLAST

Post-translational modificationi

This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation.Curated

Keywords - PTMi

Autocatalytic cleavage, Protein splicing

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ0781.

Structurei

Secondary structure

1
721
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi422 – 43211Combined sources
Turni434 – 4363Combined sources
Beta strandi446 – 4483Combined sources
Turni450 – 4523Combined sources
Beta strandi455 – 4573Combined sources
Turni461 – 4644Combined sources
Beta strandi468 – 4703Combined sources
Beta strandi473 – 4775Combined sources
Beta strandi481 – 4844Combined sources
Beta strandi501 – 5066Combined sources
Beta strandi509 – 5146Combined sources
Helixi515 – 5173Combined sources
Beta strandi522 – 5276Combined sources
Beta strandi529 – 5368Combined sources
Beta strandi542 – 5454Combined sources
Beta strandi549 – 5535Combined sources
Turni555 – 5573Combined sources
Beta strandi558 – 5647Combined sources
Beta strandi568 – 5714Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2JMZNMR-A398-577[»]
2JNQNMR-A398-577[»]
ProteinModelPortaliQ58191.
SMRiQ58191. Positions 398-577.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ58191.

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP E family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1372.
InParanoidiQ58191.
KOiK07332.
OMAiTGHDGCS.

Family and domain databases

Gene3Di2.170.16.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR028992. Hedgehog/Intein_dom.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR006141. Intein_splice_site.
IPR027417. P-loop_NTPase.
IPR001482. T2SS_protein-E.
[Graphical view]
PfamiPF00437. T2SE. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
[Graphical view]
SUPFAMiSSF51294. SSF51294. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEiPS50818. INTEIN_C_TER. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q58191-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIIKNQLIFV NFYVILIIWW FVMGILDKIQ KKSEKIEKEK KSETVIPSDT
60 70 80 90 100
KLKPIEPHPT INKKATVGND ETILDTYSIK IDEIEMEVVI KREEGYIYYL
110 120 130 140 150
VPEIDKINMS LSKLTKDHLN HIKSQISDLG LIEYDQIREY LTNFSMRYNL
160 170 180 190 200
AIPYIDSLAK FFYLVIGRLG LLEVPLNDDR LEEVMVNGYN VPVFVFHRKH
210 220 230 240 250
QMCETNIVLD RNEVDRIIES IANLVNRPID SRVPMLDAFL PDGSRVNATT
260 270 280 290 300
ADITMNGATL TIRKFSKNPL TVIDLINFGT LDIDTAAFLW QAVEGYFGAK
310 320 330 340 350
PANTLIAGGT GSGKTTLLNV LSLFSMYNER IITIEDTPEL QIPHKHVIKM
360 370 380 390 400
VTRPARPGMP EYEVTMDDLI KNALRMRPDR IFVGEVRGKE AHSLLVAMNT
410 420 430 440 450
GHDGALAYDE PIYLSDGNII NIGEFVDKFF KKYKNSIKKE DNGFGWIDIG
460 470 480 490 500
NENIYIKSFN KLSLIIEDKR ILRVWRKKYS GKLIKITTKN RREITLTHDH
510 520 530 540 550
PVYISKTGEV LEINAEMVKV GDYIYIPKNN TINLDEVIKV ETVDYNGHIY
560 570 580 590 600
DLTVEDNHTY IAGKNEGFAV SNCSGTLHAN SADEAILRLT SPPMNVPKIM
610 620 630 640 650
LTALNFIINQ QRIRRAGKTI RRILGIVEIV KGGGEGHEFA KTTLYEYNGL
660 670 680 690 700
KDSLERRGIC MWEEEVCEIA GITKEELLRD RENRKKVLSY LYKNNIRKLE
710 720
NVSDYIMRYQ VDPEKLLRSI R
Length:721
Mass (Da):82,743
Last modified:November 1, 1996 - v1
Checksum:i13B76CEC7976F0F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98770.1.
PIRiE64397.
RefSeqiNP_247766.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98770; AAB98770; MJ_0781.
GeneIDi1451658.
KEGGimja:MJ_0781.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98770.1.
PIRiE64397.
RefSeqiNP_247766.1. NC_000909.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2JMZNMR-A398-577[»]
2JNQNMR-A398-577[»]
ProteinModelPortaliQ58191.
SMRiQ58191. Positions 398-577.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243232.MJ0781.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB98770; AAB98770; MJ_0781.
GeneIDi1451658.
KEGGimja:MJ_0781.

Phylogenomic databases

eggNOGiCOG1372.
InParanoidiQ58191.
KOiK07332.
OMAiTGHDGCS.

Miscellaneous databases

EvolutionaryTraceiQ58191.

Family and domain databases

Gene3Di2.170.16.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR028992. Hedgehog/Intein_dom.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR006141. Intein_splice_site.
IPR027417. P-loop_NTPase.
IPR001482. T2SS_protein-E.
[Graphical view]
PfamiPF00437. T2SE. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
[Graphical view]
SUPFAMiSSF51294. SSF51294. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEiPS50818. INTEIN_C_TER. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Entry informationi

Entry nameiY781_METJA
AccessioniPrimary (citable) accession number: Q58191
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: January 7, 2015
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Intein-containing proteins
    List of intein-containing protein entries
  2. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.