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Q580V7 (Q580V7_TRYB2) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Cofilin/actin depolymerizing factor, putative EMBL AAX81027.1
Gene names
ORF Names:Tb927.3.5180 EMBL AAX81027.1
OrganismTrypanosoma brucei brucei (strain 927/4 GUTat10.1) [Reference proteome]
Taxonomic identifier999953 [NCBI]
Taxonomic lineageEukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma ›

Protein attributes

Sequence length136 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 ADF-H domain. SAAS SAAS017904

Ontologies

Keywords
   LigandActin-binding SAAS SAAS017904
   Technical term3D-structure PDB 2LJ8
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processactin filament depolymerization

Inferred from electronic annotation. Source: InterPro

   Cellular_componentactin cytoskeleton

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q580V7 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 076E728887BC14AD

FASTA13615,119
        10         20         30         40         50         60 
MAMSGVSVAD ECVTALNDLR HKKSRYVIMH IVDQKSIAVK TIGERGANFD QFIEAIDKNV 

        70         80         90        100        110        120 
PCYAAFDFEY TTNDGPRDKL ILISWNPDSG APRTKMLYSS SRDALVPLTQ GFQGIQANDA 

       130 
SGLDFEEISR KVKSNR

« Hide

References

« Hide 'large scale' references
[1]El-Sayed N.M., Khalak H., Adams M.D.
Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: GUTat10.1 EMBL AAX81027.1.
[2]Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G. expand/collapse author list , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A.
Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: GUTat10.1 EMBL AAX81027.1.
[3]"Comparative genomics of trypanosomatid parasitic protozoa."
El-Sayed N.M.A., Myler P.J., Blandin G., Berriman M., Crabtree J., Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C., Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.-N., Wortman J.R., Alsmark U.C.M., Angiuoli S. expand/collapse author list , Anupama A., Badger J., Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T., Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C., Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J., Salzberg S.L., Shallom J., Silva J.C., Sundaram J., Westenberger S., White O., Melville S.E., Donelson J.E., Andersson B., Stuart K.D., Hall N.
Science 309:404-409(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 927/4 GUTat10.1 EMBL AAZ10549.1.
[4]"The genome of the African trypanosome Trypanosoma brucei."
Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M. expand/collapse author list , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 927/4 GUTat10.1 EMBL AAZ10549.1.
[5]"Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2 through 8."
Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G. expand/collapse author list , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A.
Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 927/4 GUTat10.1 EMBL AAZ10549.1.
[6]Haas B., Blandin G., El-Sayed N.
Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: GUTat10.1 EMBL AAX81027.1.
[7]"1H and 15N Assigned Chemical Shifts for ADF/Cofilin from Trypanosoma brucei."
Dai K., Liao S., Zhang J., Tu X.
Submitted (SEP-2011) to the PDB data bank
Cited for: STRUCTURE BY NMR.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC093543 Genomic DNA. Translation: AAX81027.1.
CP000066 Genomic DNA. Translation: AAZ10549.1.
RefSeqXP_844108.1. XM_839015.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2LJ8NMR-A1-136[»]
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsAAZ10549; AAZ10549; Tb927.3.5180.
GeneID3656461.
KEGGtbr:Tb927.3.5180.

Phylogenomic databases

eggNOGNOG303866.
HOGENOMHOG000039697.
KOK05765.
OMAPAETHEA.
ProtClustDBCLSZ2438161.

Family and domain databases

InterProIPR002108. Actin-bd_cofilin/tropomyosin.
IPR017904. ADF/Cofilin/Destrin.
[Graphical view]
PANTHERPTHR11913. PTHR11913. 1 hit.
PfamPF00241. Cofilin_ADF. 1 hit.
[Graphical view]
SMARTSM00102. ADF. 1 hit.
[Graphical view]
PROSITEPS51263. ADF_H. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ580V7_TRYB2
AccessionPrimary (citable) accession number: Q580V7
Secondary accession number(s): D6XE72
Entry history
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 1, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info