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Q580V7

- Q580V7_TRYB2

UniProt

Q580V7 - Q580V7_TRYB2

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Protein
Submitted name:

Cofilin/actin depolymerizing factor, putative

Gene
Tb927.3.5180
Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. actin filament depolymerization Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Actin-bindingSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Cofilin/actin depolymerizing factor, putativeImported
Gene namesi
ORF Names:Tb927.3.5180Imported
OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)
Taxonomic identifieri999953 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
ProteomesiUP000008524: Chromosome 3

Subcellular locationi

GO - Cellular componenti

  1. actin cytoskeleton Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2LJ8NMR-A1-136[»]

Family & Domainsi

Sequence similaritiesi

Contains ADF-H domain.SAAS annotations

Phylogenomic databases

eggNOGiNOG303866.
HOGENOMiHOG000039697.
KOiK05765.
OMAiFLELQMK.

Family and domain databases

Gene3Di3.40.20.10. 1 hit.
InterProiIPR002108. ADF-H.
IPR029006. ADF-H/Gelsolin-like_dom.
IPR017904. ADF/Cofilin/Destrin.
[Graphical view]
PANTHERiPTHR11913. PTHR11913. 1 hit.
PfamiPF00241. Cofilin_ADF. 1 hit.
[Graphical view]
SMARTiSM00102. ADF. 1 hit.
[Graphical view]
PROSITEiPS51263. ADF_H. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q580V7-1 [UniParc]FASTAAdd to Basket

« Hide

MAMSGVSVAD ECVTALNDLR HKKSRYVIMH IVDQKSIAVK TIGERGANFD    50
QFIEAIDKNV PCYAAFDFEY TTNDGPRDKL ILISWNPDSG APRTKMLYSS 100
SRDALVPLTQ GFQGIQANDA SGLDFEEISR KVKSNR 136
Length:136
Mass (Da):15,119
Last modified:May 10, 2005 - v1
Checksum:i076E728887BC14AD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC093543 Genomic DNA. Translation: AAX81027.1.
CP000066 Genomic DNA. Translation: AAZ10549.1.
RefSeqiXP_844108.1. XM_839015.1.

Genome annotation databases

EnsemblProtistsiAAZ10549; AAZ10549; Tb927.3.5180.
GeneIDi3656461.
KEGGitbr:Tb927.3.5180.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC093543 Genomic DNA. Translation: AAX81027.1 .
CP000066 Genomic DNA. Translation: AAZ10549.1 .
RefSeqi XP_844108.1. XM_839015.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2LJ8 NMR - A 1-136 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi AAZ10549 ; AAZ10549 ; Tb927.3.5180 .
GeneIDi 3656461.
KEGGi tbr:Tb927.3.5180.

Phylogenomic databases

eggNOGi NOG303866.
HOGENOMi HOG000039697.
KOi K05765.
OMAi FLELQMK.

Family and domain databases

Gene3Di 3.40.20.10. 1 hit.
InterProi IPR002108. ADF-H.
IPR029006. ADF-H/Gelsolin-like_dom.
IPR017904. ADF/Cofilin/Destrin.
[Graphical view ]
PANTHERi PTHR11913. PTHR11913. 1 hit.
Pfami PF00241. Cofilin_ADF. 1 hit.
[Graphical view ]
SMARTi SM00102. ADF. 1 hit.
[Graphical view ]
PROSITEi PS51263. ADF_H. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. El-Sayed N.M., Khalak H., Adams M.D.
    Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GUTat10.1Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GUTat10.1Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 927/4 GUTat10.1Imported.
  4. "The genome of the African trypanosome Trypanosoma brucei."
    Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M.
    , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
    Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 927/4 GUTat10.1Imported.
  5. "Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2 through 8."
    Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G.
    , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 927/4 GUTat10.1Imported.
  6. Haas B., Blandin G., El-Sayed N.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GUTat10.1Imported.
  7. "1H and 15N Assigned Chemical Shifts for ADF/Cofilin from Trypanosoma brucei."
    Dai K., Liao S., Zhang J., Tu X.
    Submitted (SEP-2011) to the PDB data bank
    Cited for: STRUCTURE BY NMR.

Entry informationi

Entry nameiQ580V7_TRYB2
AccessioniPrimary (citable) accession number: Q580V7
Secondary accession number(s): D6XE72
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: June 11, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

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