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Q580V7

- Q580V7_TRYB2

UniProt

Q580V7 - Q580V7_TRYB2

Protein
Submitted name:

Cofilin/actin depolymerizing factor, putative

Gene

Tb927.3.5180

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. actin filament depolymerization Source: InterPro

    Keywords - Ligandi

    Actin-bindingSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cofilin/actin depolymerizing factor, putativeImported
    Gene namesi
    ORF Names:Tb927.3.5180Imported
    OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
    Taxonomic identifieri999953 [NCBI]
    Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
    ProteomesiUP000008524: Chromosome 3

    Subcellular locationi

    GO - Cellular componenti

    1. actin cytoskeleton Source: InterPro

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2LJ8NMR-A1-136[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains ADF-H domain.SAAS annotation

    Phylogenomic databases

    eggNOGiNOG303866.
    HOGENOMiHOG000039697.
    KOiK05765.
    OMAiFLELQMK.

    Family and domain databases

    Gene3Di3.40.20.10. 1 hit.
    InterProiIPR002108. ADF-H.
    IPR029006. ADF-H/Gelsolin-like_dom.
    IPR017904. ADF/Cofilin/Destrin.
    [Graphical view]
    PANTHERiPTHR11913. PTHR11913. 1 hit.
    PfamiPF00241. Cofilin_ADF. 1 hit.
    [Graphical view]
    SMARTiSM00102. ADF. 1 hit.
    [Graphical view]
    PROSITEiPS51263. ADF_H. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q580V7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAMSGVSVAD ECVTALNDLR HKKSRYVIMH IVDQKSIAVK TIGERGANFD    50
    QFIEAIDKNV PCYAAFDFEY TTNDGPRDKL ILISWNPDSG APRTKMLYSS 100
    SRDALVPLTQ GFQGIQANDA SGLDFEEISR KVKSNR 136
    Length:136
    Mass (Da):15,119
    Last modified:May 10, 2005 - v1
    Checksum:i076E728887BC14AD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC093543 Genomic DNA. Translation: AAX81027.1.
    CP000066 Genomic DNA. Translation: AAZ10549.1.
    RefSeqiXP_844108.1. XM_839015.1.

    Genome annotation databases

    EnsemblProtistsiAAZ10549; AAZ10549; Tb927.3.5180.
    GeneIDi3656461.
    KEGGitbr:Tb927.3.5180.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC093543 Genomic DNA. Translation: AAX81027.1 .
    CP000066 Genomic DNA. Translation: AAZ10549.1 .
    RefSeqi XP_844108.1. XM_839015.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2LJ8 NMR - A 1-136 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi AAZ10549 ; AAZ10549 ; Tb927.3.5180 .
    GeneIDi 3656461.
    KEGGi tbr:Tb927.3.5180.

    Phylogenomic databases

    eggNOGi NOG303866.
    HOGENOMi HOG000039697.
    KOi K05765.
    OMAi FLELQMK.

    Family and domain databases

    Gene3Di 3.40.20.10. 1 hit.
    InterProi IPR002108. ADF-H.
    IPR029006. ADF-H/Gelsolin-like_dom.
    IPR017904. ADF/Cofilin/Destrin.
    [Graphical view ]
    PANTHERi PTHR11913. PTHR11913. 1 hit.
    Pfami PF00241. Cofilin_ADF. 1 hit.
    [Graphical view ]
    SMARTi SM00102. ADF. 1 hit.
    [Graphical view ]
    PROSITEi PS51263. ADF_H. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. El-Sayed N.M., Khalak H., Adams M.D.
      Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: GUTat10.1Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: GUTat10.1Imported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 927/4 GUTat10.1Imported.
    4. "The genome of the African trypanosome Trypanosoma brucei."
      Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M.
      , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
      Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 927/4 GUTat10.1Imported.
    5. "Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2 through 8."
      Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G.
      , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A.
      Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 927/4 GUTat10.1Imported.
    6. Haas B., Blandin G., El-Sayed N.
      Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: GUTat10.1Imported.
    7. "1H and 15N Assigned Chemical Shifts for ADF/Cofilin from Trypanosoma brucei."
      Dai K., Liao S., Zhang J., Tu X.
      Submitted (SEP-2011) to the PDB data bank
      Cited for: STRUCTURE BY NMR.

    Entry informationi

    Entry nameiQ580V7_TRYB2
    AccessioniPrimary (citable) accession number: Q580V7
    Secondary accession number(s): D6XE72
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 10, 2005
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3