ID Q580K6_TRYB2 Unreviewed; 130 AA. AC Q580K6; D6XDZ2; DT 10-MAY-2005, integrated into UniProtKB/TrEMBL. DT 10-MAY-2005, sequence version 1. DT 27-MAR-2024, entry version 109. DE SubName: Full=40S ribosomal protein S15a, putative {ECO:0000313|EMBL:AAX79341.1}; GN Name=Tb03.26J7.620 {ECO:0000313|EMBL:AAZ10469.1}; GN ORFNames=Tb11.02.4000 {ECO:0000313|EMBL:EAN79576.1}, Tb927.3.4360 GN {ECO:0000313|EMBL:AAX79341.1}; OS Trypanosoma brucei brucei (strain 927/4 GUTat10.1). OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; OC Trypanosomatida; Trypanosomatidae; Trypanosoma. OX NCBI_TaxID=185431 {ECO:0000313|EMBL:AAX79341.1, ECO:0000313|Proteomes:UP000008524}; RN [1] {ECO:0000313|EMBL:AAX79341.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=GUTat10.1 {ECO:0000313|EMBL:AAX79341.1}; RA El-Sayed N.M., Khalak H., Adams M.D.; RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:AAZ10469.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ10469.1}; RX PubMed=16020724; DOI=10.1126/science.1112181; RA El-Sayed N.M., Myler P.J., Blandin G., Berriman M., Crabtree J., RA Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C., RA Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.N., RA Wortman J.R., Alsmark U.C., Angiuoli S., Anupama A., Badger J., RA Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T., RA Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C., RA Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J., Salzberg S.L., RA Shallom J., Silva J.C., Sundaram J., Westenberger S., White O., RA Melville S.E., Donelson J.E., Andersson B., Stuart K.D., Hall N.; RT "Comparative genomics of trypanosomatid parasitic protozoa."; RL Science 309:404-409(2005). RN [3] {ECO:0000313|EMBL:AAZ10469.1, ECO:0000313|Proteomes:UP000008524} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ10469.1, RC ECO:0000313|Proteomes:UP000008524}; RX PubMed=16020726; DOI=10.1126/science.1112642; RA Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., RA Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., RA Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., RA Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., RA Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., RA Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., RA Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., RA Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., RA Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., RA Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., RA Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., RA Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., RA Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., RA Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., RA Walker D., Wanless D., Wang S., White B., White O., Whitehead S., RA Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., RA Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., RA Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.; RT "The genome of the African trypanosome Trypanosoma brucei."; RL Science 309:416-422(2005). RN [4] {ECO:0000313|EMBL:AAX79341.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=GUTat10.1 {ECO:0000313|EMBL:AAX79341.1}; RA Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., RA Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., RA Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G., RA Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., RA Wortman J., Fraser C.M., El-Sayed N.M.A.; RT "."; RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. RN [5] {ECO:0000313|EMBL:AAZ10469.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:AAZ10469.1}; RA Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., RA Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., RA Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G., RA Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., RA Wortman J., Fraser C.M., El-Sayed N.M.A.; RT "Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2 RT through 8."; RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. RN [6] {ECO:0007829|PDB:4V8M} RP STRUCTURE BY ELECTRON MICROSCOPY (5.57 ANGSTROMS). RX PubMed=23395961; DOI=10.1038/nature11872; RA Hashem Y., des Georges A., Fu J., Buss S.N., Jossinet F., Jobe A., RA Zhang Q., Liao H.Y., Grassucci R.A., Bajaj C., Westhof E., RA Madison-Antenucci S., Frank J.; RT "High-resolution cryo-electron microscopy structure of the Trypanosoma RT brucei ribosome."; RL Nature 494:385-389(2013). CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS8 family. CC {ECO:0000256|ARBA:ARBA00006471, ECO:0000256|RuleBase:RU003660}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC096673; AAX79341.1; -; Genomic_DNA. DR EMBL; CP000066; AAZ10469.1; -; Genomic_DNA. DR EMBL; CH464491; EAN79576.1; -; Genomic_DNA. DR RefSeq; XP_828688.1; XM_823595.1. DR RefSeq; XP_844028.1; XM_838935.1. DR PDB; 4V8M; EM; 5.57 A; AJ=1-130. DR PDBsum; 4V8M; -. DR AlphaFoldDB; Q580K6; -. DR EMDB; EMD-17208; -. DR EMDB; EMD-17212; -. DR IntAct; Q580K6; 1. DR STRING; 185431.Q580K6; -. DR PaxDb; 5691-AAZ10469; -. DR GeneID; 3656375; -. DR GeneID; 3665648; -. DR KEGG; tbr:Tb11.02.4000; -. DR KEGG; tbr:Tb927.3.4360; -. DR VEuPathDB; TriTrypDB:Tb927.11.6140; -. DR VEuPathDB; TriTrypDB:Tb927.3.4360; -. DR eggNOG; KOG1754; Eukaryota. DR InParanoid; Q580K6; -. DR OMA; LPAKNFG; -. DR OrthoDB; 5472446at2759; -. DR Proteomes; UP000008524; Chromosome 11 Scaffold 1. DR Proteomes; UP000008524; Chromosome 3. DR GO; GO:0005737; C:cytoplasm; IDA:GeneDB. DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central. DR GO; GO:0000314; C:organellar small ribosomal subunit; ISM:GeneDB. DR GO; GO:0003735; F:structural constituent of ribosome; ISM:GeneDB. DR GO; GO:0006412; P:translation; ISM:GeneDB. DR Gene3D; 3.30.1370.30; -; 1. DR Gene3D; 3.30.1490.10; -; 1. DR InterPro; IPR000630; Ribosomal_uS8. DR InterPro; IPR047863; Ribosomal_uS8_CS. DR InterPro; IPR035987; Ribosomal_uS8_sf. DR PANTHER; PTHR11758; 40S RIBOSOMAL PROTEIN S15A; 1. DR PANTHER; PTHR11758:SF16; 40S RIBOSOMAL PROTEIN S15A; 1. DR Pfam; PF00410; Ribosomal_S8; 1. DR SUPFAM; SSF56047; Ribosomal protein S8; 1. DR PROSITE; PS00053; RIBOSOMAL_S8; 1. PE 1: Evidence at protein level; KW 3D-structure {ECO:0007829|PDB:4V8M}; KW Reference proteome {ECO:0000313|Proteomes:UP000008524}; KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, KW ECO:0000256|RuleBase:RU003660}; KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, KW ECO:0000256|RuleBase:RU003660}. SQ SEQUENCE 130 AA; 14645 MW; 05991471432979F4 CRC64; MTMMSVLANA LRCIAGAERR GKRQVLIRPS SKVVVKFLQV MQKHGYIGEF EIVDDHRAGK IVVNLNGRLN KCGAICPRFD CTARDFEKWV KNILPSRQFG FVVLTTSLGI MDHEEARARN TGGKVLGFFY //