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Protein

Probable ATP-dependent RNA helicase MJ0669

Gene

MJ0669

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi51 – 588ATPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ATP-dependent RNA helicase MJ0669 (EC:3.6.4.13)
Gene namesi
Ordered Locus Names:MJ0669
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 367367Probable ATP-dependent RNA helicase MJ0669PRO_0000055116Add
BLAST

Interactioni

Subunit structurei

Homodimer.

Protein-protein interaction databases

STRINGi243232.MJ_0669.

Structurei

Secondary structure

1
367
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi8 – 103Combined sources
Helixi15 – 2410Combined sources
Helixi31 – 4212Combined sources
Beta strandi45 – 506Combined sources
Beta strandi53 – 564Combined sources
Helixi57 – 6812Combined sources
Beta strandi71 – 744Combined sources
Beta strandi77 – 804Combined sources
Helixi84 – 9815Combined sources
Beta strandi105 – 1084Combined sources
Helixi114 – 1229Combined sources
Beta strandi125 – 1295Combined sources
Helixi131 – 1399Combined sources
Beta strandi150 – 1556Combined sources
Helixi156 – 1605Combined sources
Turni161 – 1644Combined sources
Helixi165 – 1739Combined sources
Beta strandi180 – 1845Combined sources
Helixi190 – 19910Combined sources
Beta strandi202 – 2076Combined sources
Beta strandi210 – 22011Combined sources
Helixi223 – 2253Combined sources
Helixi226 – 2349Combined sources
Beta strandi241 – 2444Combined sources
Helixi248 – 26013Combined sources
Beta strandi265 – 2684Combined sources
Beta strandi270 – 2723Combined sources
Helixi274 – 28512Combined sources
Beta strandi288 – 2947Combined sources
Helixi298 – 3014Combined sources
Beta strandi308 – 3147Combined sources
Helixi319 – 3257Combined sources
Beta strandi332 – 3343Combined sources
Beta strandi337 – 3426Combined sources
Helixi347 – 35711Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1HV8X-ray3.00A/B1-367[»]
ProteinModelPortaliQ58083.
SMRiQ58083. Positions 3-365.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ58083.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini38 – 206169Helicase ATP-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini213 – 367155Helicase C-terminalPROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi6 – 3429Q motifAdd
BLAST
Motifi154 – 1574DEAD box

Sequence similaritiesi

Belongs to the DEAD box helicase family.Curated
Contains 1 helicase ATP-binding domain.PROSITE-ProRule annotation
Contains 1 helicase C-terminal domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiarCOG00558. Archaea.
COG0513. LUCA.
InParanoidiQ58083.
KOiK05592.
OMAiKYENHTA.
PhylomeDBiQ58083.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q58083-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVEYMNFNE LNLSDNILNA IRNKGFEKPT DIQMKVIPLF LNDEYNIVAQ
60 70 80 90 100
ARTGSGKTAS FAIPLIELVN ENNGIEAIIL TPTRELAIQV ADEIESLKGN
110 120 130 140 150
KNLKIAKIYG GKAIYPQIKA LKNANIVVGT PGRILDHINR GTLNLKNVKY
160 170 180 190 200
FILDEADEML NMGFIKDVEK ILNACNKDKR ILLFSATMPR EILNLAKKYM
210 220 230 240 250
GDYSFIKAKI NANIEQSYVE VNENERFEAL CRLLKNKEFY GLVFCKTKRD
260 270 280 290 300
TKELASMLRD IGFKAGAIHG DLSQSQREKV IRLFKQKKIR ILIATDVMSR
310 320 330 340 350
GIDVNDLNCV INYHLPQNPE SYMHRIGRTG RAGKKGKAIS IINRREYKKL
360
RYIERAMKLK IKKLKFG
Length:367
Mass (Da):41,920
Last modified:November 1, 1997 - v1
Checksum:i1B9102E8DF50CB37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98663.1.
PIRiE64383.

Genome annotation databases

EnsemblBacteriaiAAB98663; AAB98663; MJ_0669.
KEGGimja:MJ_0669.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98663.1.
PIRiE64383.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1HV8X-ray3.00A/B1-367[»]
ProteinModelPortaliQ58083.
SMRiQ58083. Positions 3-365.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243232.MJ_0669.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB98663; AAB98663; MJ_0669.
KEGGimja:MJ_0669.

Phylogenomic databases

eggNOGiarCOG00558. Archaea.
COG0513. LUCA.
InParanoidiQ58083.
KOiK05592.
OMAiKYENHTA.
PhylomeDBiQ58083.

Miscellaneous databases

EvolutionaryTraceiQ58083.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.
  2. "Crystal structure of a DEAD box protein from the hyperthermophile Methanococcus jannaschii."
    Story R.M., Li H., Abelson J.N.
    Proc. Natl. Acad. Sci. U.S.A. 98:1465-1470(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS).

Entry informationi

Entry nameiH669_METJA
AccessioniPrimary (citable) accession number: Q58083
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: February 17, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.