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Reviewed, UniProtKB/Swiss-Prot Q58065 (NAOX_METJA)

Last modified November 25, 2008. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Putative NADH oxidase
      Short name=NOXase
    EC=1.6.99.3
Gene names
Ordered Locus Names: MJ0649
OrganismMethanocaldococcus jannaschii (Methanococcus jannaschii) [Complete proteome] [HAMAP]
Taxonomic identifier2190 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length448 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the four-electron reduction of molecular oxygen to water By similarity.

Catalytic activity

NADH + acceptor = NAD(+) + reduced acceptor.

Cofactor

Binds 1 FAD per subunit By similarity.

Sequence similarities

Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 448448Putative NADH oxidase
PRO_0000184704

Regions

Nucleotide binding7 – 115FAD By similarity
Nucleotide binding110 – 1134FAD By similarity
Nucleotide binding152 – 16716NAD By similarity
Nucleotide binding271 – 28111FAD By similarity

Sites

Active site421Redox-active
Binding site421FAD By similarity
Binding site1321FAD By similarity
Binding site2431NAD; via amide nitrogen By similarity

Amino acid modifications

Modified residue421Cysteine sulfenic acid (-SOH) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q58065-1 [UniParc].

Last modified March 1, 2005. Version 2.
Checksum: 8790664DF98D9DCD

FASTA44848,876
        10         20         30         40         50         60 
MRAIIIGSGA AGLTTASTIR KYNKDMEIVV ITKEKEIAYS PCAIPYVIEG AIKSFDDIIM 

        70         80         90        100        110        120 
HTPEDYKRER NIDILTETTV IDVDSKNNKI KCVDKDGNEF EMNYDYLVLA TGAEPFIPPI 

       130        140        150        160        170        180 
EGKDLDGVFK VRTIEDGRAI LKYIEENGCK KVAVVGAGAI GLEMAYGLKC RGLDVLVVEM 

       190        200        210        220        230        240 
APQVLPRFLD PDMAEIVQKY LEKEGIKVML SKPLEKIVGK EKVEAVYVDG KLYDVDMVIM 

       250        260        270        280        290        300 
ATGVRPNIEL AKKAGCKIGK FAIEVNEKMQ TSIPNIYAVG DCVEVIDFIT GEKTLSPFGT 

       310        320        330        340        350        360 
AAVRQGKVAG KNIAGVEAKF YPVLNSAVSK IGDLEIGGTG LTAFSANLKR IPIVIGRAKA 

       370        380        390        400        410        420 
LTRARYYPGG KEIEIKMIFN EDGKVVGCQI VGGERVAERI DAMSIAIFKK VSAEELANME 

       430        440 
FCYAPPVSMV HEPLSLAAED ALKKLSNK 

« Hide

Cross-references

Sequence databases

L77117 Genomic DNA. Translation: AAB98641.1. Different initiation.
PIRA64381.
RefSeqNP_247633.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1451515.
GenomeReviewsGene locus MJ0649 in contig L77117_GR.
KEGGmja:MJ0649.
NMPDRfig|243232.1.peg.670.
TIGRMJ0649.

Phylogenomic databases

HOGENOMQ58065.

Enzyme and pathway databases

BioCycMJAN243232:MJ_0649-MON.

Family and domain databases

InterProIPR000759. Adrndx_reductase.
IPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR001100. Pyr_nuc-diS_OxRdtase.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR001327. Pyr_OxRdtase_NAD_bd.
[Graphical view]
Gene3DG3DSA:3.30.390.30. Pyr_redox_dim. 1 hit.
PfamPF00070. Pyr_redox. 2 hits.
PF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
[Graphical view]
PRINTSPR00419. ADXRDTASE.
PR00368. FADPNR.
PR00411. PNDRDTASEI.
ProDomPD000139. FAD_pyr_redox. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameNAOX_METJA
AccessionPrimary (citable) accession number: Q58065
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: March 1, 2005
Last modified: November 25, 2008
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents