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Q58051

- Y634_METJA

UniProt

Q58051 - Y634_METJA

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Protein

Uncharacterized KamA family protein MJ0634

Gene

MJ0634

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • [4Fe-4S] clusterBy similarityNote: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.By similarity
  • pyridoxal 5'-phosphateBy similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi338 – 3381Iron-sulfur (4Fe-4S-S-AdoMet)Sequence Analysis
Metal bindingi342 – 3421Iron-sulfur (4Fe-4S-S-AdoMet)Sequence Analysis
Metal bindingi345 – 3451Iron-sulfur (4Fe-4S-S-AdoMet)Sequence Analysis

GO - Molecular functioni

  1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  2. catalytic activity Source: InterPro
  3. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding, Pyridoxal phosphate, S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized KamA family protein MJ0634
Gene namesi
Ordered Locus Names:MJ0634
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 620620Uncharacterized KamA family protein MJ0634PRO_0000172295Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei552 – 5521N6-(pyridoxal phosphate)lysineBy similarity

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ0634.

Structurei

3D structure databases

ProteinModelPortaliQ58051.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the radical SAM superfamily. KamA family.Curated

Phylogenomic databases

eggNOGiCOG1509.
InParanoidiQ58051.
KOiK01843.
OMAiTFYPKGK.
PhylomeDBiQ58051.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR006638. Elp3/MiaB/NifB.
IPR003739. Lysine_aminomutase_fam.
IPR007197. rSAM.
[Graphical view]
PfamiPF04055. Radical_SAM. 1 hit.
[Graphical view]
SMARTiSM00729. Elp3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00238. TIGR00238. 1 hit.

Sequencei

Sequence statusi: Complete.

Q58051-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTIKSMTEYE TISYKTFLDI FSPLPEIGEI LEESESVEEA REKLFEFCKE
60 70 80 90 100
LEWEIRMGRI KFDNEVDRWL ALKAIEVFLN IISKDNERLA GFSTLEYLWK
110 120 130 140 150
AYKGDEEALK EIREGFIEEF RHLFLAMSGK ADYSLGFLGK RLLEEGVKFI
160 170 180 190 200
DFSKIKGREA GIARSNFLDK VYEIMREYIS RYPSGLDKRI ILKRKKNREI
210 220 230 240 250
LEEFFGITDE EWFNYKWQFK NVLRGLKGVK ILRELREVTN FKISDEDLEI
260 270 280 290 300
IEKAVKNGIP FGLTPYYLHL FDFENPYVED LAVRRQVIPP EWYVEKMIEH
310 320 330 340 350
KEDRNIAFDF MGEHDTSPID LVTRRYVTIA IIKPYESCPQ ICVYCQRNWM
360 370 380 390 400
VQDFDAKAFP GWEKVEKALD WFAEHDSMIE ILITGGDPFS LSDKAIEKML
410 420 430 440 450
NRIAEMNHVV GVRFGTRTIV TAPMRITDEL AELLGSFEKS LMISTHVESC
460 470 480 490 500
YEITPEVAEA VKKLRTNNIY IYNQHVFHRY VSRRFENVAL RIALKKVGII
510 520 530 540 550
PYYTFYPKGK MEHKDYLVPI ARLAQEVKEE ARLLPGSFRT DEPIFNVPRM
560 570 580 590 600
GKNHLRAWQD RELIAIKPNG SRVYLMHPWE KGIYPTKLYT YEDVPIKEYL
610 620
DSLKEIGENI EEYKTIWYYY
Length:620
Mass (Da):73,372
Last modified:November 1, 1996 - v1
Checksum:i4A5E12147E5F159C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98629.1.
PIRiB64379.
RefSeqiNP_247618.1. NC_000909.1.
WP_010870139.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98629; AAB98629; MJ_0634.
GeneIDi1451500.
KEGGimja:MJ_0634.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98629.1 .
PIRi B64379.
RefSeqi NP_247618.1. NC_000909.1.
WP_010870139.1. NC_000909.1.

3D structure databases

ProteinModelPortali Q58051.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243232.MJ0634.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB98629 ; AAB98629 ; MJ_0634 .
GeneIDi 1451500.
KEGGi mja:MJ_0634.

Phylogenomic databases

eggNOGi COG1509.
InParanoidi Q58051.
KOi K01843.
OMAi TFYPKGK.
PhylomeDBi Q58051.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR006638. Elp3/MiaB/NifB.
IPR003739. Lysine_aminomutase_fam.
IPR007197. rSAM.
[Graphical view ]
Pfami PF04055. Radical_SAM. 1 hit.
[Graphical view ]
SMARTi SM00729. Elp3. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00238. TIGR00238. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Entry informationi

Entry nameiY634_METJA
AccessioniPrimary (citable) accession number: Q58051
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 26, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3