Q58051 (Y634_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized KamA family protein MJ0634

Gene names

Ordered Locus Names:

MJ0634

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus › Methanocaldococcus jannaschii

Protein attributes

Sequence length	620 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine By similarity. Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the radical SAM superfamily. KamA family.

Ontologies

Keywords
Ligand	4Fe-4S Iron Iron-sulfur Metal-binding Pyridoxal phosphate S-adenosyl-L-methionine
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	metabolic process Inferred from electronic annotation. Source: GOC
Molecular_function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW catalytic activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 620	620	Uncharacterized KamA family protein MJ0634		PRO_0000172295
Sites
	Metal binding	338	1	Iron-sulfur (4Fe-4S-S-AdoMet) Potential
	Metal binding	342	1	Iron-sulfur (4Fe-4S-S-AdoMet) Potential
	Metal binding	345	1	Iron-sulfur (4Fe-4S-S-AdoMet) Potential
Amino acid modifications
	Modified residue	552	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q58051 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 4A5E12147E5F159C	FASTA	620	73,372
	10 20 30 40 50 60 MTIKSMTEYE TISYKTFLDI FSPLPEIGEI LEESESVEEA REKLFEFCKE LEWEIRMGRI 70 80 90 100 110 120 KFDNEVDRWL ALKAIEVFLN IISKDNERLA GFSTLEYLWK AYKGDEEALK EIREGFIEEF 130 140 150 160 170 180 RHLFLAMSGK ADYSLGFLGK RLLEEGVKFI DFSKIKGREA GIARSNFLDK VYEIMREYIS 190 200 210 220 230 240 RYPSGLDKRI ILKRKKNREI LEEFFGITDE EWFNYKWQFK NVLRGLKGVK ILRELREVTN 250 260 270 280 290 300 FKISDEDLEI IEKAVKNGIP FGLTPYYLHL FDFENPYVED LAVRRQVIPP EWYVEKMIEH 310 320 330 340 350 360 KEDRNIAFDF MGEHDTSPID LVTRRYVTIA IIKPYESCPQ ICVYCQRNWM VQDFDAKAFP 370 380 390 400 410 420 GWEKVEKALD WFAEHDSMIE ILITGGDPFS LSDKAIEKML NRIAEMNHVV GVRFGTRTIV 430 440 450 460 470 480 TAPMRITDEL AELLGSFEKS LMISTHVESC YEITPEVAEA VKKLRTNNIY IYNQHVFHRY 490 500 510 520 530 540 VSRRFENVAL RIALKKVGII PYYTFYPKGK MEHKDYLVPI ARLAQEVKEE ARLLPGSFRT 550 560 570 580 590 600 DEPIFNVPRM GKNHLRAWQD RELIAIKPNG SRVYLMHPWE KGIYPTKLYT YEDVPIKEYL 610 620 DSLKEIGENI EEYKTIWYYY

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98629.1.
PIR	B64379.
RefSeq	NP_247618.1. NC_000909.1.
3D structure databases
ProteinModelPortal	Q58051.
ModBase	Search...
Protein-protein interaction databases
STRING	243232.MJ0634.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAB98629; AAB98629; MJ_0634.
GeneID	1451500.
KEGG	mja:MJ_0634.
Phylogenomic databases
eggNOG	COG1509.
KO	K01843.
OMA	RHLFLAM.
ProtClustDB	CLSK876273.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
InterPro	IPR013785. Aldolase_TIM. IPR006638. Elp3/MiaB/NifB. IPR003739. Lysine_aminomutase_fam. IPR007197. rSAM. [Graphical view]
Pfam	PF04055. Radical_SAM. 1 hit. [Graphical view]
SMART	SM00729. Elp3. 1 hit. [Graphical view]
TIGRFAMs	TIGR00238. TIGR00238. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Y634_METJA

Accession

Primary (citable) accession number: Q58051

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	May 1, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program