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Q58017 (T2M3_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type-2 restriction enzyme MjaIII

Short name=R.MjaIII
EC=3.1.21.4
Alternative name(s):
Endonuclease MjaIII
Type II restriction enzyme MjaIII
Gene names
Name:mjaIIIR
Ordered Locus Names:MJ0600
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length290 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1.

Catalytic activity

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Sequence similarities

Belongs to the type II restriction enzyme DpnII family.

Ontologies

Keywords
   Biological processRestriction system
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA restriction-modification system

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: InterPro

Type II site-specific deoxyribonuclease activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 290290Type-2 restriction enzyme MjaIII
PRO_0000077334

Sequences

Sequence LengthMass (Da)Tools
Q58017 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: ACEBAE31B029900D

FASTA29034,392
        10         20         30         40         50         60 
MNFEYIINSL LETIKTYNFF VDWEKIENNI KKIEKRLHIL NYLIGKENFK EEFFELLKEY 

        70         80         90        100        110        120 
PEVITVFPIL IAVRDNKITI LNENMELETL EFKEKKYLTD EEIERYYKFF KETGLEDLLK 

       130        140        150        160        170        180 
NRKIKNLVDY VFGVEVGMDT NARKNRIGDL MENIVKKYIE NLCKQNKNLD YIFQATKDKI 

       190        200        210        220        230        240 
KQKWGINLTL DKTNRKFDFA VFNKNTKKLY LIEVNFYSGG GSKLKATAGE YRSLNEFIKN 

       250        260        270        280        290 
NNNNVQFIWI TDGKGWNTAK NPLKESFNSG VVILNLKMVK EGLLKEILTQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB98591.1.
PIRH64374.
RefSeqNP_247582.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ58017.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ0600.

Protein family/group databases

REBASE3891. MjaIII.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB98591; AAB98591; MJ_0600.
GeneID1451465.
KEGGmja:MJ_0600.

Phylogenomic databases

eggNOGNOG12396.
KOK01155.
OMATNYYGGG.

Family and domain databases

InterProIPR021191. Restrct_endonuc_II_DpmII.
IPR007637. Restrct_endonuc_II_DpmII-like.
[Graphical view]
PfamPF04556. DpnII. 1 hit.
[Graphical view]
PIRSFPIRSF016080. Restrict_endonuc_II_DpmII. 1 hit.
ProtoNetSearch...

Entry information

Entry nameT2M3_METJA
AccessionPrimary (citable) accession number: Q58017
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 14, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Restriction enzymes and methylases

Classification of restriction enzymes and methylases and list of entries

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names