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Q57XJ2

- Q57XJ2_TRYB2

UniProt

Q57XJ2 - Q57XJ2_TRYB2

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Protein
Submitted name:

Trans-sialidase

Gene

Tb927.7.6850

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
  2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
  3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC
  4. exo-alpha-sialidase activity Source: GeneDB_Tbrucei
  5. sialyltransferase activity Source: GeneDB_Tbrucei

GO - Biological processi

  1. pathogenesis Source: GeneDB_Tbrucei
  2. sialic acid transport Source: GeneDB_Tbrucei
  3. sialylation Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Protein family/group databases

CAZyiGH33. Glycoside Hydrolase Family 33.

Names & Taxonomyi

Protein namesi
Submitted name:
Trans-sialidaseImported (EC:3.2.1.18Imported)
Gene namesi
ORF Names:Tb927.7.6850Imported
OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
Taxonomic identifieri185431 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
ProteomesiUP000008524: Chromosome 7

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: GeneDB_Tbrucei
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG4409.
HOGENOMiHOG000137392.
KOiK01186.
OMAiHEQNIDE.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PTHR10628:SF5. PTHR10628:SF5. 1 hit.
PRINTSiPR01803. TCSIALIDASE.
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

Q57XJ2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEELHQQMRM PISRLLLIFT AVCHCCALTS KAAGKGTTRE AFLSGGAWAL
60 70 80 90 100
RKKLSEKDGE VWWWQDGPNW KDKYDKEWER WFKEEKGPWG GSEKRSEWFA
110 120 130 140 150
RMTGGYITLG KTKILSSAIE GSDKVERTVH SFRIPSFVEV DGVLMGIGDA
160 170 180 190 200
RYLTSTDYFF TDTVAKYSAD GGKTWKTEVI IENGRVDPTY SRVVDPTVVA
210 220 230 240 250
KADSVFVLVA RYNVTKGYWH NENNAAGIAD WEPFMYKGVV TKGADGKTSD
260 270 280 290 300
VRISWTKTPL KPLYDFTVAG SKGTQFIGGA GNGVVTLNGT ILFPVQARNE
310 320 330 340 350
DNAVVSMVMY SVDDGVSWHF ARGETALLTS EASLTEWNGK LLMSARTDTS
360 370 380 390 400
GVNVEGGFRK VFESNNLGAT WEESLGTISR VIGNSPDRTK PSPTANYPGS
410 420 430 440 450
SGALITVTLG DVPVMLITHP KNTKGAWSRD RLQLWMTDGN RMWLVGQISE
460 470 480 490 500
GDDNSAYSSL LLARDGLLYC LHEQNIDEVY GLHLVHLVDE LEKVNATVRK
510 520 530 540 550
WKAQDALLAG LCSSSRKKND PTCSGVPTDG LVGLLAGPVG ASVWADVYDC
560 570 580 590 600
VNASISDGVK VSEGVQLGGK RNSRVLWPVS EQGQDQRYYF ANTHFTLLAT
610 620 630 640 650
VRFAGEPKAE APLMGFSNAE GKTSETLSLT VGGKKWVLTY GSVRKEGPTT
660 670 680 690 700
SMDWNQTHQI ALTLRDGKVD AHVNGELIIK EVSVGASESS AHLHLSHFFI
710 720 730 740 750
GAPVNDSGEG GNNVIVRNVL LYNRKLDEDE LQLLYSNREK IQPVVSAVGI
760 770
PEGMSAPRLC CLLILMYVLA I
Length:771
Mass (Da):84,544
Last modified:May 10, 2005 - v1
Checksum:i4E8C55C6FEEACDC6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC159415 Genomic DNA. Translation: AAX69677.1.
CP000070 Genomic DNA. Translation: AAZ12746.1.
RefSeqiXP_846305.1. XM_841212.1.

Genome annotation databases

GeneIDi3658905.
KEGGitbr:Tb927.7.6850.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC159415 Genomic DNA. Translation: AAX69677.1 .
CP000070 Genomic DNA. Translation: AAZ12746.1 .
RefSeqi XP_846305.1. XM_841212.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH33. Glycoside Hydrolase Family 33.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3658905.
KEGGi tbr:Tb927.7.6850.

Phylogenomic databases

eggNOGi COG4409.
HOGENOMi HOG000137392.
KOi K01186.
OMAi HEQNIDE.

Family and domain databases

Gene3Di 2.120.10.10. 1 hit.
2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
PTHR10628:SF5. PTHR10628:SF5. 1 hit.
PRINTSi PR01803. TCSIALIDASE.
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 927/4 GUTat10.1Imported.
  2. "The genome of the African trypanosome Trypanosoma brucei."
    Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M.
    , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
    Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 927/4 GUTat10.1Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GUTat10.1Imported.

Entry informationi

Entry nameiQ57XJ2_TRYB2
AccessioniPrimary (citable) accession number: Q57XJ2
Secondary accession number(s): D6XJL3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: October 29, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3