Q57W56 (Q57W56_TRYB2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
60S ribosomal protein L2, putative EMBL AAX70163.1

Gene names

ORF Names:

Tb11.01.7960 EMBL EAN80573.1, Tb927.5.1110 EMBL AAX70163.1

Organism

Trypanosoma brucei brucei (strain 927/4 GUTat10.1) [Reference proteome]

Taxonomic identifier

999953 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma › Trypanozoon › Trypanosoma brucei › Trypanosoma brucei brucei

Protein attributes

Sequence length	260 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Ribonucleoprotein Ribosomal protein EMBL AAX70163.1
Technical term	3D-structure PDB 3ZF7 Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: InterPro
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q57W56 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 5A4AAC32A0D58406	FASTA	260	28,314
	10 20 30 40 50 60 MGKTVLTCRK GNGSVYQVHG HKRLGPAKLR ILDYAERHGF MRGVVKAIEH EPGRGAPLAR 70 80 90 100 110 120 VEFRHPYKYR RVKELMVAPE GMFTGQSMLC GVKAPLAIGN VLPLGQITEG CIVCNVEAKV 130 140 150 160 170 180 GDRGTLARAS GDYCIIISHN TETGRTRLKL PSGQKKTVPS SCRAMIGIVA GGGRIEKPVL 190 200 210 220 230 240 KAGNSFYRFR GKRNCWPKVR GVARNPVEHP HGGGNHQHIG HPSTVSRHAP PGQKVGLIAA 250 260 RRTGRIRGSR AVRGAWHPEE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparative genomics of trypanosomatid parasitic protozoa." El-Sayed N.M.A., Myler P.J., Blandin G., Berriman M., Crabtree J., Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C., Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.-N., Wortman J.R., Alsmark U.C.M., Angiuoli S. , Anupama A., Badger J., Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T., Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C., Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J., Salzberg S.L., Shallom J., Silva J.C., Sundaram J., Westenberger S., White O., Melville S.E., Donelson J.E., Andersson B., Stuart K.D., Hall N. Science 309:404-409(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 927/4 GUTat10.1 EMBL AAZ11226.1.
[2]	"The genome of the African trypanosome Trypanosoma brucei." Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M. , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A. Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 927/4 GUTat10.1 EMBL AAZ11226.1.
[3]	"Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2 through 8." Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G. , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 927/4 GUTat10.1 EMBL AAZ11226.1.
[4]	Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G. , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: GUTat10.1 EMBL AAX70163.1.
[5]	"High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome." Hashem Y., des Georges A., Fu J., Buss S.N., Jossinet F., Jobe A., Zhang Q., Liao H.Y., Grassucci R.A., Bajaj C., Westhof E., Madison-Antenucci S., Frank J. Nature 494:385-389(2013) [PubMed] [Europe PMC] [Abstract] Cited for: STRUCTURE BY ELECTRON MICROSCOPY (5.57 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AC159432 Genomic DNA. Translation: AAX70163.1.
CP000068 Genomic DNA. Translation: AAZ11226.1.
CH464491 Genomic DNA. Translation: EAN80573.1.

RefSeq

XP_829685.1. XM_824592.1.
XP_844785.1. XM_839692.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3ZF7	electron microscopy	5.57	e	1-260	[»]

SMR

Q57W56. Positions 2-246.

ModBase

Search...

Protein-protein interaction databases

STRING

5691.Tb927.5.1110.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblProtists

AAZ11226; AAZ11226; Tb927.5.1110.
EAN80573; EAN80573; Tb11.01.7960.

GeneID

3657206.
3664518.

KEGG

tbr:Tb11.01.7960.
tbr:Tb927.5.1110.

Organism-specific databases

EuPathDB

TriTrypDB:Tb927.5.1110.

Phylogenomic databases

eggNOG

COG0090.

HOGENOM

HOG000232983.

KO

K02938.

OMA

GRVIRNQ.

ProtClustDB

PTZ00180.

Family and domain databases

Gene3D

2.30.30.30. 1 hit.
2.40.50.140. 1 hit.
4.10.950.10. 1 hit.

InterPro

IPR012340. NA-bd_OB-fold.
IPR022666. Rbsml_prot_L2_RNA-bd_dom.
IPR014722. Rib_L2_dom2.
IPR002171. Ribosomal_L2.
IPR022669. Ribosomal_L2_C.
IPR022671. Ribosomal_L2_CS.
IPR014726. Ribosomal_L2_dom3.
IPR008991. Translation_prot_SH3-like.
[Graphical view]

PANTHER

PTHR13691. PTHR13691. 1 hit.

Pfam

PF00181. Ribosomal_L2. 1 hit.
PF03947. Ribosomal_L2_C. 1 hit.
[Graphical view]

PIRSF

PIRSF002158. Ribosomal_L2. 1 hit.

SUPFAM

SSF50249. Nucleic_acid_OB. 1 hit.
SSF50104. Transl_SH3_like. 1 hit.

PROSITE

PS00467. RIBOSOMAL_L2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q57W56_TRYB2

Accession

Primary (citable) accession number: Q57W56
Secondary accession number(s): D6XG49

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)