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Q57TY5

- Q57TY5_TRYB2

UniProt

Q57TY5 - Q57TY5_TRYB2

Protein
Submitted name:

Trans-sialidase, putative

Gene

Tb927.7.7480

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
    2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
    3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pathogenesis Source: InterPro

    Keywords - Molecular functioni

    GlycosidaseImported, Hydrolase

    Protein family/group databases

    CAZyiGH33. Glycoside Hydrolase Family 33.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Trans-sialidase, putativeImported (EC:3.2.1.18Imported)
    Gene namesi
    ORF Names:Tb927.7.7480Imported
    OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
    Taxonomic identifieri999953 [NCBI]
    Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
    ProteomesiUP000008524: Chromosome 7

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG4409.
    HOGENOMiHOG000137392.
    KOiK01186.

    Family and domain databases

    Gene3Di2.120.10.10. 1 hit.
    2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR026856. Sialidase_fam.
    IPR008377. Sialidase_trypan.
    IPR011040. Sialidases.
    [Graphical view]
    PANTHERiPTHR10628. PTHR10628. 1 hit.
    PTHR10628:SF5. PTHR10628:SF5. 1 hit.
    PRINTSiPR01803. TCSIALIDASE.
    SUPFAMiSSF49899. SSF49899. 1 hit.
    SSF50939. SSF50939. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q57TY5-1 [UniParc]FASTAAdd to Basket

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    MERLQVRMGT LSLTSPFSML AYPFLPCTVV ILSVLSFCCG IVSSKIYEKT    50
    TREVFLEGGR WVRKSEWEKG SWKTSPEWNA GYEWWAWCMD SVAKEAKGEV 100
    CRKEWLSQRK KGYTLVPRTK VPFREKNGTQ WMRNVHSFRV PSFVEVSGVL 150
    VGIADVRYIS SADFTFTETV AKYSADGGDT WKTKVIIENS RVNTNFSRVV 200
    DPTVAVKGNN IFVLVGRYNT SSKYWTWQHY GEDWDILMYK GTVIKEEKDG 250
    NVTASITFEA PQNLKFLLAT VPSPGGHPPS QFLGGVGNAA VTPDGAIVFS 300
    VQVKNTWNHV VGKLLYSTDD GKTWHFGAGE TPVGSTESSV VWWKDRLLVN 350
    ARTAEYVGYR RVFETSDLGN TLKESISTLS RVIGNSPLRN QPGSSGSAIS 400
    ITVEGMDVML ISQPKNEKGS FSRDHLQLWL TDGTRVFLVG QISQGDDNSP 450
    YSSLLYTSDG KLYCLYEQKI EEVFTIYLAR LVDEMKMIKR VVLLWKAQDA 500
    LLVGDCLSSV GGTRPCKGIP VGDLAGLLTG PAVGHVWPDV YKCVNASVSG 550
    AVDNKRGVVL GGTSGSSVVW PVSEQGQDQR YYFANTHFTI VATVQFGAVP 600
    QRDTPLIGFV NGEKNANKLF ILSIENTRWT LMYGEKCSEG SPVPSNLEET 650
    HQIALALQDG LVVAYVDGKL AVAAINVSES DRVDLLNIRH FFVGTPASSD 700
    LSDHTSITVH SVLLYNRRLS EGELQLVFTN REVIRAANPT TPLPVSSRVA 750
    AGAGRQSHDG VFFTFGDHVS SVRSRYSDGG ILEYVYLLSV ISLCALTLFI 800
    LTLVFQRRRD VVPTNI 816
    Length:816
    Mass (Da):90,234
    Last modified:May 10, 2005 - v1
    Checksum:i5A232168125F4CBB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC159702 Genomic DNA. Translation: AAX79971.1.
    CP000070 Genomic DNA. Translation: AAZ12809.1.
    RefSeqiXP_846368.1. XM_841275.1.

    Genome annotation databases

    EnsemblProtistsiAAZ12809; AAZ12809; Tb927.7.7480.
    GeneIDi3658977.
    KEGGitbr:Tb927.7.7480.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC159702 Genomic DNA. Translation: AAX79971.1 .
    CP000070 Genomic DNA. Translation: AAZ12809.1 .
    RefSeqi XP_846368.1. XM_841275.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH33. Glycoside Hydrolase Family 33.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi AAZ12809 ; AAZ12809 ; Tb927.7.7480 .
    GeneIDi 3658977.
    KEGGi tbr:Tb927.7.7480.

    Phylogenomic databases

    eggNOGi COG4409.
    HOGENOMi HOG000137392.
    KOi K01186.

    Family and domain databases

    Gene3Di 2.120.10.10. 1 hit.
    2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR026856. Sialidase_fam.
    IPR008377. Sialidase_trypan.
    IPR011040. Sialidases.
    [Graphical view ]
    PANTHERi PTHR10628. PTHR10628. 1 hit.
    PTHR10628:SF5. PTHR10628:SF5. 1 hit.
    PRINTSi PR01803. TCSIALIDASE.
    SUPFAMi SSF49899. SSF49899. 1 hit.
    SSF50939. SSF50939. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 927/4 GUTat10.1Imported.
    2. "The genome of the African trypanosome Trypanosoma brucei."
      Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M.
      , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
      Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 927/4 GUTat10.1Imported.
    3. "Sequencing, closure, and annotation of Trypanosoma brucei chromosomes 2 through 8."
      Ghedin E., Blandin G., Bartholomeu D., Caler E., Haas B., Hannick L., Shallom J., Hou L., Djikeng A., Feldblyum T., Hostetler J., Johnson J., Jones K., Koo H.L., Larkin C., Pai G., Peterson J., Khalak H.G.
      , Salzberg S., Simpson A.J., Tallon L., Van Aken S., Wanless D., White O., Wortman J., Fraser C.M., El-Sayed N.M.A.
      Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 927/4 GUTat10.1Imported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: GUTat10.1Imported.

    Entry informationi

    Entry nameiQ57TY5_TRYB2
    AccessioniPrimary (citable) accession number: Q57TY5
    Secondary accession number(s): D6XJS6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 10, 2005
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3