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Q57TY5

- Q57TY5_TRYB2

UniProt

Q57TY5 - Q57TY5_TRYB2

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Protein
Submitted name:

Trans-sialidase, putative

Gene

Tb927.7.7480

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
  2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
  3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC

GO - Biological processi

  1. pathogenesis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Protein family/group databases

CAZyiGH33. Glycoside Hydrolase Family 33.

Names & Taxonomyi

Protein namesi
Submitted name:
Trans-sialidase, putativeImported (EC:3.2.1.18Imported)
Gene namesi
ORF Names:Tb927.7.7480Imported
OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
Taxonomic identifieri185431 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
ProteomesiUP000008524: Chromosome 7

Family & Domainsi

Phylogenomic databases

eggNOGiCOG4409.
HOGENOMiHOG000137392.
KOiK01186.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PTHR10628:SF5. PTHR10628:SF5. 1 hit.
PRINTSiPR01803. TCSIALIDASE.
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

Q57TY5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MERLQVRMGT LSLTSPFSML AYPFLPCTVV ILSVLSFCCG IVSSKIYEKT
60 70 80 90 100
TREVFLEGGR WVRKSEWEKG SWKTSPEWNA GYEWWAWCMD SVAKEAKGEV
110 120 130 140 150
CRKEWLSQRK KGYTLVPRTK VPFREKNGTQ WMRNVHSFRV PSFVEVSGVL
160 170 180 190 200
VGIADVRYIS SADFTFTETV AKYSADGGDT WKTKVIIENS RVNTNFSRVV
210 220 230 240 250
DPTVAVKGNN IFVLVGRYNT SSKYWTWQHY GEDWDILMYK GTVIKEEKDG
260 270 280 290 300
NVTASITFEA PQNLKFLLAT VPSPGGHPPS QFLGGVGNAA VTPDGAIVFS
310 320 330 340 350
VQVKNTWNHV VGKLLYSTDD GKTWHFGAGE TPVGSTESSV VWWKDRLLVN
360 370 380 390 400
ARTAEYVGYR RVFETSDLGN TLKESISTLS RVIGNSPLRN QPGSSGSAIS
410 420 430 440 450
ITVEGMDVML ISQPKNEKGS FSRDHLQLWL TDGTRVFLVG QISQGDDNSP
460 470 480 490 500
YSSLLYTSDG KLYCLYEQKI EEVFTIYLAR LVDEMKMIKR VVLLWKAQDA
510 520 530 540 550
LLVGDCLSSV GGTRPCKGIP VGDLAGLLTG PAVGHVWPDV YKCVNASVSG
560 570 580 590 600
AVDNKRGVVL GGTSGSSVVW PVSEQGQDQR YYFANTHFTI VATVQFGAVP
610 620 630 640 650
QRDTPLIGFV NGEKNANKLF ILSIENTRWT LMYGEKCSEG SPVPSNLEET
660 670 680 690 700
HQIALALQDG LVVAYVDGKL AVAAINVSES DRVDLLNIRH FFVGTPASSD
710 720 730 740 750
LSDHTSITVH SVLLYNRRLS EGELQLVFTN REVIRAANPT TPLPVSSRVA
760 770 780 790 800
AGAGRQSHDG VFFTFGDHVS SVRSRYSDGG ILEYVYLLSV ISLCALTLFI
810
LTLVFQRRRD VVPTNI
Length:816
Mass (Da):90,234
Last modified:May 10, 2005 - v1
Checksum:i5A232168125F4CBB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC159702 Genomic DNA. Translation: AAX79971.1.
CP000070 Genomic DNA. Translation: AAZ12809.1.
RefSeqiXP_846368.1. XM_841275.1.

Genome annotation databases

GeneIDi3658977.
KEGGitbr:Tb927.7.7480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC159702 Genomic DNA. Translation: AAX79971.1 .
CP000070 Genomic DNA. Translation: AAZ12809.1 .
RefSeqi XP_846368.1. XM_841275.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH33. Glycoside Hydrolase Family 33.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3658977.
KEGGi tbr:Tb927.7.7480.

Phylogenomic databases

eggNOGi COG4409.
HOGENOMi HOG000137392.
KOi K01186.

Family and domain databases

Gene3Di 2.120.10.10. 1 hit.
2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
PTHR10628:SF5. PTHR10628:SF5. 1 hit.
PRINTSi PR01803. TCSIALIDASE.
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 927/4 GUTat10.1Imported.
  2. "The genome of the African trypanosome Trypanosoma brucei."
    Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M.
    , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
    Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 927/4 GUTat10.1Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GUTat10.1Imported.

Entry informationi

Entry nameiQ57TY5_TRYB2
AccessioniPrimary (citable) accession number: Q57TY5
Secondary accession number(s): D6XJS6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: October 29, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3