Reviewed, UniProtKB/Swiss-Prot Q57TI8 (CAIA_SALCH)

Names and origin

Protein names

Recommended name:
    Crotonobetainyl-CoA dehydrogenase
    EC=1.3.99.-
Alternative name(s):
    Crotonobetainyl-CoA reductase

Gene names

Name:	caiA
Ordered Locus Names:	SCH_0067

Organism

Salmonella choleraesuis [Complete proteome] [HAMAP]

Taxonomic identifier

28901 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA By similarity.
Cofactor	FAD By similarity.
Pathway	Amine and polyamine metabolism; carnitine metabolism. HAMAP MF_01052
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the acyl-CoA dehydrogenase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	FAD binding Inferred from electronic annotation. Source: InterPro acyl-CoA dehydrogenase activity Inferred from electronic annotation. Source: HAMAP electron carrier activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 380	380	Crotonobetainyl-CoA dehydrogenase HAMAP MF_01052		PRO_1000064350

Sequences

	Sequence		Length	Mass (Da)
	Q57TI8-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 4A7A39798EDFC806	FASTA	380	42,481
	10 20 30 40 50 60 MDFNLNDEQE LFVAGIRELM ASENWEAYFA ECDRDSVYPE RFVKALADMG IDSLLIPEEH 70 80 90 100 110 120 GGLEAGFVTV AAVWMELGRL GAPTYVLYQL PGGFNTFLRE GTQEQIDKIM AFRGTGKQMW 130 140 150 160 170 180 NSAITEPGAG SDVGSLKTTY TRKNGKVYLN GSKCFITSSA YTPYIVVMAR DGASPDKPVY 190 200 210 220 230 240 TEWFVDMSKA GIKVNKLEKL GLRMDSCCEI TFDDVELDEK DMFGREGNGF NRVKEEFDHE 250 260 270 280 290 300 RFLVALTNYG TAMCAFEDAA RYANQRVQFG EAIGRFQLIQ EKFAHMAIKL NSMKNMLLEA 310 320 330 340 350 360 AWKADNGTIT SGDAAMCKYF CANAAFEVVD TAMQVLGGVG IAGNHRITRF WRDLRVDRVS 370 380 GGSDEMQILT LGRAVLKQYR

References

[1]

"The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen." Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S., Lee Y.-S. Nucleic Acids Res. 33:1690-1698(2005) [PubMed: 15781495] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC-B67.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017220 Genomic DNA. Translation: AAX63973.1.
RefSeq	YP_215054.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3332477.
GenomeReviews	Gene locus SCH_0067 in contig AE017220_GR.
KEGG	sec:SC0067.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q57TI8.
OMA	Q57TI8. IFTEWFV.
Enzyme and pathway databases
BioCyc	SENT321314:SCH_0067-MON.
Family and domain databases
HAMAP	MF_01052. [Tree]
InterPro	IPR006089. Acyl-CoA_DH_CS. IPR006092. Acyl-CoA_DH_N. IPR006090. Acyl-CoA_Oxase/DH_1. IPR006091. Acyl-CoA_Oxase/DH_M. IPR013786. AcylCoA_DH/ox_N. IPR013764. AcylCoA_oxidase/DH_1/2_C. [Graphical view]
Gene3D	G3DSA:2.40.110.10. Acyl_CoA_DH/ox_M. 1 hit. G3DSA:1.10.540.10. AcylCoA_DH/ox_N. 1 hit. G3DSA:1.20.140.10. AcylCoA_DH_1/2_C. 1 hit.
Pfam	PF00441. Acyl-CoA_dh_1. 1 hit. PF02770. Acyl-CoA_dh_M. 1 hit. PF02771. Acyl-CoA_dh_N. 1 hit. [Graphical view]
PROSITE	PS00072. ACYL_COA_DH_1. 1 hit. PS00073. ACYL_COA_DH_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAIA_SALCH

Accession

Primary (citable) accession number: Q57TI8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	May 10, 2005
Last modified:	June 16, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)