Q57TF9 (ARAA_SALCH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
L-arabinose isomerase
EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	SCH_0096

Organism

Salmonella choleraesuis [Complete proteome] [HAMAP]

Taxonomic identifier

28901 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity. HAMAP MF_00519
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity. HAMAP MF_00519
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Subunit structure	Homohexamer By similarity. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: UniProtKB-KW fucose metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: EC L-fucose isomerase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	L-arabinose isomerase HAMAP MF_00519		PRO_0000259341
Sites
	Metal binding	306	1	Manganese By similarity
	Metal binding	333	1	Manganese By similarity
	Metal binding	350	1	Manganese By similarity
	Metal binding	450	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q57TF9 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 987C7BCF851ED9D3	FASTA	500	55,893
	10 20 30 40 50 60 MTIFDNYEVW FVIGSQHLYG AETLRQVTQH AEHVVNALNT EAKLPCKLVL KPLGTSPDEI 70 80 90 100 110 120 TAICRDANYD DRCAGLVVWL HTFSPAKMWI NGLSILNKPL LQFHTQFNAA LPWDSIDMDF 130 140 150 160 170 180 MNLNQTAHGG REFGFIGARM RQQHAVVTGH WQDKEAHTRI GAWMRQAVSK QDTRQLKVCR 190 200 210 220 230 240 FGDNMREVAV TDGDKVAAQI KFGFSVNTWA VGDLVQVVNS IGDGDINALI DEYESSYTLT 250 260 270 280 290 300 PATQIHGDKR QNVREAARIE LGMKRFLEQG GFHAFTTTFE DLHGLKQLPG LAVQRLMQQG 310 320 330 340 350 360 YGFAGEGDWK TAALLRIMKV MSTGLQGGTS FMEDYTYHFE KGNDLVLGSH MLEVCPSIAV 370 380 390 400 410 420 EEKLILDVQH LGIGGKEDPA RLIFNTQTGP AIVASLIDLG DRYRLLVNCI DTVKTPHSLP 430 440 450 460 470 480 KLPVANALWK AQPDLPTASE AWILAGGAHH TVFSHALDLN DMRQFAEIHD IEIAVIDNDT 490 500 RLPAFKDALR WNEVYYGLKR

References

[1]

"The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen." Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S., Lee Y.-S. Nucleic Acids Res. 33:1690-1698(2005) [PubMed: 15781495] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC-B67.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017220 Genomic DNA. Translation: AAX64002.1.
RefSeq	YP_215083.1. NC_006905.1.
3D structure databases
HSSP	HSSP built from PDB template 2AJT based on UniProtKB P08202.
ProteinModelPortal	Q57TF9.
SMR	Q57TF9. Positions 1-498.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3332506.
GenomeReviews	Gene locus SCH_0096 in contig AE017220_GR.
KEGG	sec:SC0096.
NMPDR	fig|321314.4.peg.229.
PATRIC	32320623. VBISalEnt136302_0339.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG297198.
OMA	EVCPTIA.
PhylomeDB	Q57TF9.
ProtClustDB	PRK02929.
Enzyme and pathway databases
BioCyc	SENT321314:SCH_0096-MONOMER.
Family and domain databases
HAMAP	MF_00519. Arabinose_Isome. [Tree]
InterPro	IPR024664. Ara_Isoase_C. IPR004216. Fuc/Ara_isomerase_C. IPR009015. Fucose_isomerase_N/cen. IPR003762. Lara_isomerase. [Graphical view]
KO	K01804.
Pfam	PF11762. Arabinose_Iso_C. 1 hit. PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF50443. Fuc_isomerase_C. 1 hit. SSF53743. Fuc_isomerase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAA_SALCH

Accession

Primary (citable) accession number: Q57TF9

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	May 10, 2005
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program