Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q57T26

- LPXB_SALCH

UniProt

Q57T26 - LPXB_SALCH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Salmonella choleraesuis (strain SC-B67)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

Catalytic activityi

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciSENT321314:GJCS-236-MONOMER.
UniPathwayiUPA00359; UER00481.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
Gene namesi
Name:lpxBUniRule annotation
Ordered Locus Names:SCH_0229
OrganismiSalmonella choleraesuis (strain SC-B67)
Taxonomic identifieri321314 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000000538: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 382382Lipid-A-disaccharide synthasePRO_0000255221Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi321314.SC0229.

Structurei

3D structure databases

ProteinModelPortaliQ57T26.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LpxB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0763.
OMAiVSPITYR.
OrthoDBiEOG6FBWZR.

Family and domain databases

HAMAPiMF_00392. LpxB.
InterProiIPR003835. Glyco_trans_19.
[Graphical view]
PfamiPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00215. lpxB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q57T26-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAAQRPLTIA LVAGETSGDI LGAGLIRALK ARVPNARFVG VAGPRMQAEG
60 70 80 90 100
CEAWYEMEEL AVMGIVEVLG RLRRLLHIRA DLTRRFTELK PDVFVGIDAP
110 120 130 140 150
DFNITLEGNL KKQGIKTIHY VSPSVWAWRQ KRVFKIGRST HMVLAFLPFE
160 170 180 190 200
KAFYDKFNVP CRFIGHTMAD AMPLDPDKNA ARDVLGIPHD AHCLALLPGS
210 220 230 240 250
RGAEVEMLSA DFLKTAQLLR QRYPDLEVVV PLVNAKRREQ FEKIKAEVAP
260 270 280 290 300
DLAVHLLDGM AREAMIASDA ALLASGTAAL ECMLAKCPMV VGYRMKPFTF
310 320 330 340 350
WLAKRLVKTE YVSLPNLLAG RELVKELLQE ECEPQKLAEA LLPLLANGKT
360 370 380
SHAMHDTFRE LHQQIRCNAD EQAADAVLEL AQ
Length:382
Mass (Da):42,452
Last modified:May 10, 2005 - v1
Checksum:iD844CCF247939FE3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017220 Genomic DNA. Translation: AAX64135.1.
RefSeqiYP_215216.1. NC_006905.1.

Genome annotation databases

EnsemblBacteriaiAAX64135; AAX64135; SCH_0229.
PATRICi32320906. VBISalEnt136302_0480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017220 Genomic DNA. Translation: AAX64135.1 .
RefSeqi YP_215216.1. NC_006905.1.

3D structure databases

ProteinModelPortali Q57T26.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 321314.SC0229.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX64135 ; AAX64135 ; SCH_0229 .
PATRICi 32320906. VBISalEnt136302_0480.

Phylogenomic databases

eggNOGi COG0763.
OMAi VSPITYR.
OrthoDBi EOG6FBWZR.

Enzyme and pathway databases

UniPathwayi UPA00359 ; UER00481 .
BioCyci SENT321314:GJCS-236-MONOMER.

Family and domain databases

HAMAPi MF_00392. LpxB.
InterProi IPR003835. Glyco_trans_19.
[Graphical view ]
Pfami PF02684. LpxB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00215. lpxB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen."
    Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S., Lee Y.-S.
    Nucleic Acids Res. 33:1690-1698(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC-B67.

Entry informationi

Entry nameiLPXB_SALCH
AccessioniPrimary (citable) accession number: Q57T26
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 10, 2005
Last modified: October 1, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3