Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q57I11

- DGOD_SALCH

UniProt

Q57I11 - DGOD_SALCH

Protein

D-galactonate dehydratase

Gene

dgoD

Organism
Salmonella choleraesuis (strain SC-B67)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.UniRule annotation

    Catalytic activityi

    D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O.UniRule annotation

    Cofactori

    Binds 1 magnesium ion per subunit.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi183 – 1831MagnesiumUniRule annotation
    Active sitei185 – 1851Proton donorBy similarity
    Metal bindingi209 – 2091MagnesiumUniRule annotation
    Metal bindingi235 – 2351MagnesiumUniRule annotation
    Sitei258 – 2581Increases basicity of active site HisUniRule annotation
    Active sitei285 – 2851Proton acceptorBy similarity
    Sitei310 – 3101Transition state stabilizerUniRule annotation

    GO - Molecular functioni

    1. galactonate dehydratase activity Source: UniProtKB-HAMAP
    2. magnesium ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. cellular amino acid catabolic process Source: InterPro
    2. D-galactonate catabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Lyase

    Keywords - Ligandi

    Magnesium, Metal-binding

    Enzyme and pathway databases

    BioCyciSENT321314:GJCS-3906-MONOMER.
    UniPathwayiUPA00081; UER00518.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    D-galactonate dehydrataseUniRule annotation (EC:4.2.1.6UniRule annotation)
    Short name:
    GalDUniRule annotation
    Gene namesi
    Name:dgoDUniRule annotation
    Ordered Locus Names:SCH_3745
    OrganismiSalmonella choleraesuis (strain SC-B67)
    Taxonomic identifieri321314 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000000538: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 382382D-galactonate dehydratasePRO_0000352633Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi321314.SC3745.

    Structurei

    3D structure databases

    ProteinModelPortaliQ57I11.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG4948.
    OMAiPWQCKEF.
    OrthoDBiEOG6C015P.

    Family and domain databases

    Gene3Di3.20.20.120. 1 hit.
    3.30.390.10. 1 hit.
    HAMAPiMF_01289. Galacton_dehydrat.
    InterProiIPR029065. Enolase_C-like.
    IPR029017. Enolase_N_like.
    IPR023592. Galactonate_deHydtase.
    IPR018110. Mandel_Rmase/mucon_lact_enz_CS.
    IPR013342. Mandelate_racemase_C.
    IPR013341. Mandelate_racemase_N.
    IPR001354. MR_MLE.
    [Graphical view]
    PANTHERiPTHR13794. PTHR13794. 1 hit.
    PfamiPF02746. MR_MLE_N. 1 hit.
    [Graphical view]
    SMARTiSM00922. MR_MLE. 1 hit.
    [Graphical view]
    SUPFAMiSSF51604. SSF51604. 1 hit.
    SSF54826. SSF54826. 1 hit.
    PROSITEiPS00908. MR_MLE_1. 1 hit.
    PS00909. MR_MLE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q57I11-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKITHITTYR LPPRWMFLKI ETDEGVVGWG EPVIESRART VEAAVHEFAD    50
    YLIGKDPARI NDLWQVMYRA GFYRGGPIMM SAIAGIDQAL WDIKGKVLNA 100
    PVWQLMGGLV RDKIKAYSWV GGDRPADVID GIEKLRGIGF DTFKLNGCEE 150
    MGVIDNSRAV DAAVNTVAQI REAFGSEIEF GLDFHGRVSA PMAKVLIKEL 200
    EPYRPLFIEE PVLAEQAEYY PRLAAQTHIP IAAGERMFSR FEFKRVLDAG 250
    GLAILQPDLS HAGGITECYK IAGMAEAYDV ALAPHCPLGP IALAACLHID 300
    FVSRNAVFQE QSMGIHYNKG AELLDFVKNK EDFSMDGGFF KPLTKPGLGV 350
    DIDEARVIEL SKSAPDWRNP LWRHADGSVA EW 382
    Length:382
    Mass (Da):42,409
    Last modified:May 10, 2005 - v1
    Checksum:iF59896248E4865BC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017220 Genomic DNA. Translation: AAX67651.1.
    RefSeqiWP_001541161.1. NC_006905.1.
    YP_218732.1. NC_006905.1.

    Genome annotation databases

    EnsemblBacteriaiAAX67651; AAX67651; SCH_3745.
    PATRICi32328776. VBISalEnt136302_4331.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017220 Genomic DNA. Translation: AAX67651.1 .
    RefSeqi WP_001541161.1. NC_006905.1.
    YP_218732.1. NC_006905.1.

    3D structure databases

    ProteinModelPortali Q57I11.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 321314.SC3745.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAX67651 ; AAX67651 ; SCH_3745 .
    PATRICi 32328776. VBISalEnt136302_4331.

    Phylogenomic databases

    eggNOGi COG4948.
    OMAi PWQCKEF.
    OrthoDBi EOG6C015P.

    Enzyme and pathway databases

    UniPathwayi UPA00081 ; UER00518 .
    BioCyci SENT321314:GJCS-3906-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.120. 1 hit.
    3.30.390.10. 1 hit.
    HAMAPi MF_01289. Galacton_dehydrat.
    InterProi IPR029065. Enolase_C-like.
    IPR029017. Enolase_N_like.
    IPR023592. Galactonate_deHydtase.
    IPR018110. Mandel_Rmase/mucon_lact_enz_CS.
    IPR013342. Mandelate_racemase_C.
    IPR013341. Mandelate_racemase_N.
    IPR001354. MR_MLE.
    [Graphical view ]
    PANTHERi PTHR13794. PTHR13794. 1 hit.
    Pfami PF02746. MR_MLE_N. 1 hit.
    [Graphical view ]
    SMARTi SM00922. MR_MLE. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51604. SSF51604. 1 hit.
    SSF54826. SSF54826. 1 hit.
    PROSITEi PS00908. MR_MLE_1. 1 hit.
    PS00909. MR_MLE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen."
      Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S., Lee Y.-S.
      Nucleic Acids Res. 33:1690-1698(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC-B67.

    Entry informationi

    Entry nameiDGOD_SALCH
    AccessioniPrimary (citable) accession number: Q57I11
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 14, 2008
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Reaction proceeds via an anti dehydration.UniRule annotation

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3