Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q57H06 (G6PI_SALCH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:SCH_4100
OrganismSalmonella choleraesuis (strain SC-B67) [Complete proteome] [HAMAP]
Taxonomic identifier321314 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180720

Sites

Active site3551Proton donor By similarity
Active site3861 By similarity
Active site5141 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q57H06 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 1B361C118BABD867

FASTA54961,466
        10         20         30         40         50         60 
MKNINPTQTS AWQALQKHYD EMKDVTIAEL FANDSDRFAK FSATFDDLML VDFSKNRITE 

        70         80         90        100        110        120 
ETLAKLQDLA KETDLAGAIK SMFSGEKINR TEDRAVLHVA LRNRSNTPII VDGKDVMPEV 

       130        140        150        160        170        180 
NAVLEKMKTF SQAIISGQWK GYTGKAITDV VNIGIGGSDL GPFMVTEALR PYKNHLNMHF 

       190        200        210        220        230        240 
VSNVDGTHIA EVLKKVNPET TLFLVASKTF TTQETMTNAH SARDWFLKTA GDEKHVAKHF 

       250        260        270        280        290        300 
AALSTNVKAV GEFGIDTANM FEFWDWVGGR YSLWSAIGLS IILSVGFDNF VELLSGAHAM 

       310        320        330        340        350        360 
DKHFSTTPTE KNLPILLALI GIWYNNFFGA ETEAILPYDQ YMHRFAAYLQ QGNMESNGKY 

       370        380        390        400        410        420 
VDRNGNAVDY QTGPIIWGEP GTNGQHAFYQ LIHQGTKMVP CDFIAPAITH NPLSDHHQKL 

       430        440        450        460        470        480 
LSNFFAQTEA LAFGKSREVV EQEYRDQGKD PAQLEHVVPF KVFEGNRPTN SILLREITPF 

       490        500        510        520        530        540 
SLGALIALYE HKIFTQGVIL NIFTFDQWGV ELGKQLANRI LPELGDDKAI SSHDSSTNGL 


INRYKAWRA 

« Hide

References

[1]"The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen."
Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S., Lee Y.-S.
Nucleic Acids Res. 33:1690-1698(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC-B67.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017220 Genomic DNA. Translation: AAX68006.1.
RefSeqYP_219087.1. NC_006905.1.

3D structure databases

ProteinModelPortalQ57H06.
SMRQ57H06. Positions 7-548.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING321314.SC4100.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX68006; AAX68006; SCH_4100.
PATRIC32329615. VBISalEnt136302_4722.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
OMALKMHFVS.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycSENT321314:GJCS-4296-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_SALCH
AccessionPrimary (citable) accession number: Q57H06
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: May 10, 2005
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways