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Q57FU7 (DNAE2_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Error-prone DNA polymerase

EC=2.7.7.7
Gene names
Name:dnaE2
Ordered Locus Names:BruAb1_0069
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length1077 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP-Rule MF_01902

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP-Rule MF_01902

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01902.

Sequence similarities

Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10771077Error-prone DNA polymerase HAMAP-Rule MF_01902
PRO_0000103370

Sequences

Sequence LengthMass (Da)Tools
Q57FU7 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 174FFECD599A8B3A

FASTA1,077120,966
        10         20         30         40         50         60 
MVPYFEMAAA SNFSFLCGAS HPQELVERAH ALDLSGIGIA DRNTLAGVVR AHAQWKDIRK 

        70         80         90        100        110        120 
ESGFRLFIGC RLSFIDGTPD MVVYPRDRAA YGQLCRLLTE GKHRAAIKGE CHLEWADLLF 

       130        140        150        160        170        180 
RARQFQIAVF PPDEDEPDFA ARLTEIAQAA PGSVWLALTM PHQGQDGRRA ERIARFAAQA 

       190        200        210        220        230        240 
GVPLIATNDV LYHHPDRRPL QDVLTATRHH TTVFAAGRLL EKNAERHLKP PHEMVRLFRD 

       250        260        270        280        290        300 
YPEAIAATAD FVAPITFQLD ELKYAYPDEP IPPGKTAQQH LYDLVWEGAA RHYGADMIPP 

       310        320        330        340        350        360 
KVQGLINKEL ALIARLEYEP YFLTVYDIVT HAREKGILCQ GRGSAANSVV CFCLGITGVN 

       370        380        390        400        410        420 
PTQVDLLFER FISAERKEPP DIDVDFEHER REEVMQYVYD RYSRDRAAIV ATVISYRSRS 

       430        440        450        460        470        480 
AIRDVGKALG LSEDVTAALA NTVWGLSGGG IDRQHIRQAG LDPDNPIIQR AVELAITLIG 

       490        500        510        520        530        540 
FPRHLSQHVG GFVLTRDRLD ETVPIGPAAM DKRSFIEWDK DDIDEVGLMK VDVLSLGMLT 

       550        560        570        580        590        600 
CIRKAFDLIH QHKPQLYGGE KLTLASLPRK DKAVYDMLCK GDSLGVFQVE SRAQMNMLPR 

       610        620        630        640        650        660 
LRPQEFYDLV IEVAIVRPGP IQGDMVHPYL RRRSGQEPCT LPSPSPQHGP ANELQQILGK 

       670        680        690        700        710        720 
TKGVPLFQEQ AMRIAMEAAK FTPEEANQLR RAMATFRKMG TIHTMEKKMI DGMVNRGYDR 

       730        740        750        760        770        780 
TFAENCFNQI KGFGEYGFPE SHAASFAHLV YISAWLKCHH PEVFAAALLN SQPMGFYAPA 

       790        800        810        820        830        840 
QIVRDAREHG VTVLPVDVNF SQWDNILEET PDVHLALRLG FRQIDGFSKR DTELLIADRQ 

       850        860        870        880        890        900 
EPYRTIEDMH RRLRLDRRAF TLLADADAFG SLDIDRRAAL WAVRRLPNDE TLPLFRAAAA 

       910        920        930        940        950        960 
SELAQEPRTK LPEMAASEHV IADYETTRLS LKGHPLQYLR EGLAAEGVST CRAVQEGADG 

       970        980        990       1000       1010       1020 
RRMKVAGVVT VRQRPGSAKG VVFLTIEDET GIANIVIWPK IMKVFRREVM SARLIHIEGR 

      1030       1040       1050       1060       1070 
IQRSLEGVVH LVAAKLQDRS AALIEMSGRE AQRLIAPSQM AHHPRNVRVM PNSRDFH 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017223 Genomic DNA. Translation: AAX73487.1.
RefSeqYP_220848.1. NC_006932.1.

3D structure databases

ProteinModelPortalQ57FU7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262698.BruAb1_0069.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX73487; AAX73487; BruAb1_0069.
GeneID3339320.
KEGGbmb:BruAb1_0069.
PATRIC17821659. VBIBruAbo15061_0074.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0587.
HOGENOMHOG000021783.
KOK14162.
OMAGIVRAWQ.
OrthoDBEOG6CZQGR.
ProtClustDBPRK05672.

Enzyme and pathway databases

BioCycBABO262698:GJC2-70-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_01902. DNApol_error_prone.
InterProIPR011708. DNA_pol3_alpha.
IPR023073. DNA_pol_error_prone.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA.
IPR003141. Pol/His_phosphatase_N.
IPR016195. Pol/histidinol_Pase-like.
IPR004805. PolC_alpha.
[Graphical view]
PfamPF07733. DNA_pol3_alpha. 1 hit.
PF01336. tRNA_anti-codon. 1 hit.
[Graphical view]
SMARTSM00481. POLIIIAc. 1 hit.
[Graphical view]
SUPFAMSSF89550. SSF89550. 2 hits.
TIGRFAMsTIGR00594. polc. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDNAE2_BRUAB
AccessionPrimary (citable) accession number: Q57FU7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: May 10, 2005
Last modified: February 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names