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Q57EY0

- ATP6_BRUAB

UniProt

Q57EY0 - ATP6_BRUAB

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Protein

ATP synthase subunit a

Gene
atpB, BruAb1_0407
Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane By similarity.UniRule annotation

GO - Molecular functioni

  1. proton-transporting ATP synthase activity, rotational mechanism Source: UniProtKB-HAMAP

GO - Biological processi

  1. plasma membrane ATP synthesis coupled proton transport Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

ATP synthesis, Hydrogen ion transport, Ion transport, Transport

Enzyme and pathway databases

BioCyciBABO262698:GJC2-413-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit a
Alternative name(s):
ATP synthase F0 sector subunit a
F-ATPase subunit 6
Gene namesi
Name:atpB
Ordered Locus Names:BruAb1_0407
OrganismiBrucella abortus biovar 1 (strain 9-941)
Taxonomic identifieri262698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000540: Chromosome I

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei26 – 4621Helical; Reviewed predictionAdd
BLAST
Transmembranei84 – 10421Helical; Reviewed predictionAdd
BLAST
Transmembranei114 – 13421Helical; Reviewed predictionAdd
BLAST
Transmembranei143 – 16321Helical; Reviewed predictionAdd
BLAST
Transmembranei185 – 20521Helical; Reviewed predictionAdd
BLAST
Transmembranei208 – 22821Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
  3. proton-transporting ATP synthase complex, coupling factor F(o) Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, CF(0), Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 249249ATP synthase subunit aUniRule annotationPRO_0000362252Add
BLAST

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.

Protein-protein interaction databases

STRINGi262698.BruAb1_0407.

Structurei

3D structure databases

ProteinModelPortaliQ57EY0.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase A chain family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0356.
HOGENOMiHOG000253874.
KOiK02108.
OMAiFPYIFTL.
OrthoDBiEOG6K4054.

Family and domain databases

Gene3Di1.20.120.220. 1 hit.
HAMAPiMF_01393. ATP_synth_a_bact.
InterProiIPR000568. ATPase_F0-cplx_asu.
IPR023011. ATPase_F0-cplx_asu_AS.
[Graphical view]
PANTHERiPTHR11410. PTHR11410. 1 hit.
PfamiPF00119. ATP-synt_A. 1 hit.
[Graphical view]
PRINTSiPR00123. ATPASEA.
SUPFAMiSSF81336. SSF81336. 1 hit.
TIGRFAMsiTIGR01131. ATP_synt_6_or_A. 1 hit.
PROSITEiPS00449. ATPASE_A. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q57EY0-1 [UniParc]FASTAAdd to Basket

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MANDPIHQFQ VSRWIPIDVG GVDLSFTNVS AFMVATVVLA SGFLYLTSSG    50
RGLIPTRLQS VSEMAYEFVA TSLRDSAGSK GMKFFPFVFS LFMFVLVANF 100
IGLFPYFYTV TSQIIVTFAL SLLVIGTVIF YGFFKHGFGF LKLFVPSGVP 150
GIIVPLVVLI EIISFLSRPI SLSVRLFANM LAGHITLKVF AGFVVSLSSL 200
GALGIGGAVL PLLMTVAITA LEFLVAFLQA YVFTVLTCMY INDAVHPGH 249
Length:249
Mass (Da):26,979
Last modified:May 10, 2005 - v1
Checksum:i0322177F778BAE6D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017223 Genomic DNA. Translation: AAX73804.1.
RefSeqiYP_221165.1. NC_006932.1.

Genome annotation databases

EnsemblBacteriaiAAX73804; AAX73804; BruAb1_0407.
GeneIDi3340848.
KEGGibmb:BruAb1_0407.
PATRICi17822396. VBIBruAbo15061_0435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017223 Genomic DNA. Translation: AAX73804.1 .
RefSeqi YP_221165.1. NC_006932.1.

3D structure databases

ProteinModelPortali Q57EY0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 262698.BruAb1_0407.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX73804 ; AAX73804 ; BruAb1_0407 .
GeneIDi 3340848.
KEGGi bmb:BruAb1_0407.
PATRICi 17822396. VBIBruAbo15061_0435.

Phylogenomic databases

eggNOGi COG0356.
HOGENOMi HOG000253874.
KOi K02108.
OMAi FPYIFTL.
OrthoDBi EOG6K4054.

Enzyme and pathway databases

BioCyci BABO262698:GJC2-413-MONOMER.

Family and domain databases

Gene3Di 1.20.120.220. 1 hit.
HAMAPi MF_01393. ATP_synth_a_bact.
InterProi IPR000568. ATPase_F0-cplx_asu.
IPR023011. ATPase_F0-cplx_asu_AS.
[Graphical view ]
PANTHERi PTHR11410. PTHR11410. 1 hit.
Pfami PF00119. ATP-synt_A. 1 hit.
[Graphical view ]
PRINTSi PR00123. ATPASEA.
SUPFAMi SSF81336. SSF81336. 1 hit.
TIGRFAMsi TIGR01131. ATP_synt_6_or_A. 1 hit.
PROSITEi PS00449. ATPASE_A. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
    Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
    J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 9-941.

Entry informationi

Entry nameiATP6_BRUAB
AccessioniPrimary (citable) accession number: Q57EY0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 10, 2005
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 9-941
    Brucella abortus (strain 9-941): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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