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Q57EY0 (ATP6_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATP synthase subunit a
Alternative name(s):
ATP synthase F0 sector subunit a
F-ATPase subunit 6
Gene names
Name:atpB
Ordered Locus Names:BruAb1_0407
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length249 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane By similarity. HAMAP-Rule MF_01393

Subunit structure

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01393.

Sequence similarities

Belongs to the ATPase A chain family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 249249ATP synthase subunit a HAMAP-Rule MF_01393
PRO_0000362252

Regions

Transmembrane26 – 4621Helical; Potential
Transmembrane84 – 10421Helical; Potential
Transmembrane114 – 13421Helical; Potential
Transmembrane143 – 16321Helical; Potential
Transmembrane185 – 20521Helical; Potential
Transmembrane208 – 22821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q57EY0 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 0322177F778BAE6D

FASTA24926,979
        10         20         30         40         50         60 
MANDPIHQFQ VSRWIPIDVG GVDLSFTNVS AFMVATVVLA SGFLYLTSSG RGLIPTRLQS 

        70         80         90        100        110        120 
VSEMAYEFVA TSLRDSAGSK GMKFFPFVFS LFMFVLVANF IGLFPYFYTV TSQIIVTFAL 

       130        140        150        160        170        180 
SLLVIGTVIF YGFFKHGFGF LKLFVPSGVP GIIVPLVVLI EIISFLSRPI SLSVRLFANM 

       190        200        210        220        230        240 
LAGHITLKVF AGFVVSLSSL GALGIGGAVL PLLMTVAITA LEFLVAFLQA YVFTVLTCMY 


INDAVHPGH 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017223 Genomic DNA. Translation: AAX73804.1.
RefSeqYP_221165.1. NC_006932.1.

3D structure databases

ProteinModelPortalQ57EY0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262698.BruAb1_0407.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX73804; AAX73804; BruAb1_0407.
GeneID3340848.
KEGGbmb:BruAb1_0407.
PATRIC17822396. VBIBruAbo15061_0435.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0356.
HOGENOMHOG000253874.
KOK02108.
OMAFPYIFTL.
OrthoDBEOG6K4054.

Enzyme and pathway databases

BioCycBABO262698:GJC2-413-MONOMER.

Family and domain databases

Gene3D1.20.120.220. 1 hit.
HAMAPMF_01393. ATP_synth_a_bact.
InterProIPR000568. ATPase_F0-cplx_asu.
IPR023011. ATPase_F0-cplx_asu_AS.
[Graphical view]
PANTHERPTHR11410. PTHR11410. 1 hit.
PfamPF00119. ATP-synt_A. 1 hit.
[Graphical view]
PRINTSPR00123. ATPASEA.
SUPFAMSSF81336. SSF81336. 1 hit.
TIGRFAMsTIGR01131. ATP_synt_6_or_A. 1 hit.
PROSITEPS00449. ATPASE_A. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATP6_BRUAB
AccessionPrimary (citable) accession number: Q57EY0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 10, 2005
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names