Reviewed, UniProtKB/Swiss-Prot Q57EX8 (ATPF_BRUAB)

Names and origin

Protein names

Recommended name:
    ATP synthase subunit b
Alternative name(s):
    ATP synthase F(0) sector subunit b
    F-type ATPase subunit b
      Short name=F-ATPase subunit b
    ATPase subunit I

Gene names

Name:	atpF
Ordered Locus Names:	BruAb1_0409

Organism

Brucella abortus [Complete proteome] [HAMAP]

Taxonomic identifier

235 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	208 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	F1F0 ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F1 containing the extramembraneous catalytic core and F0 containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation By similarity. Component of the F0 channel, it forms part of the peripheral stalk, linking F1 to F0 By similarity.
Subunit structure	F-type ATPases have 2 components, F1 - the catalytic core - and F0 - the membrane proton channel. F1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. F0 has three main subunits: a1, b2 and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F1 is attached to F0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.
Subcellular location	Cell inner membrane; Single-pass membrane protein By similarity.
Sequence similarities	Belongs to the ATPase B chain family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(0) Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW proton-transporting ATP synthase complex, coupling factor F(o) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 208	208	ATP synthase subunit b HAMAP MF_01398		PRO_0000368364
Regions
	Transmembrane	56 – 78	23	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q57EX8-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 0EE57A31D20BC6E8	FASTA	208	21,896
	10 20 30 40 50 60 MFVSTAFAQT ATESQPASTA GEHGAADAVH TETGVAHDAG HGSGVFPPFD STHYASQVLW 70 80 90 100 110 120 LAITFGLFYL FLSRVVLPRI GGVIETRRDR IAQDLEQAAR LKQDADNAIA AYEQELAQAR 130 140 150 160 170 180 SKAASIAEAA REKGKGEADA ERASAEAVLE SKLKEAEERI AAIKAKAMSD VGNIAEETTA 190 200 TIVEQLLGLT ADKASVSEAV KAIRASNA

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941 / Biovar 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017223 Genomic DNA. Translation: AAX73806.1.
RefSeq	YP_221167.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3339441.
GenomeReviews	Gene locus BruAb1_0409 in contig AE017223_GR.
KEGG	bmb:BruAb1_0409.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q57EX8.
OMA	KRSGTID
Enzyme and pathway databases
BioCyc	BABO262698:BRUAB1_0409-MON.
Family and domain databases
HAMAP	MF_01398. [Tree]
InterPro	IPR002146. ATPase_F0-cplx_b/b'su_bac. [Graphical view]
Pfam	PF00430. ATP-synt_B. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATPF_BRUAB

Accession

Primary (citable) accession number: Q57EX8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	May 10, 2005
Last modified:	November 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)