Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Replicative DNA helicase

Gene

dnaB

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HelicaseUniRule annotationImported, Hydrolase

Keywords - Biological processi

DNA replicationUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-binding, DNA-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Replicative DNA helicaseUniRule annotation (EC:3.6.4.12UniRule annotation)
Gene namesi
Name:dnaBImported
Ordered Locus Names:BruAb1_0472Imported
OrganismiBrucella abortus biovar 1 (strain 9-941)Imported
Taxonomic identifieri262698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000540 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

PrimosomeUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ57ER7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini195 – 494SF4 helicaseInterPro annotationAdd BLAST300

Sequence similaritiesi

Belongs to the helicase family. DnaB subfamily.UniRule annotation
Contains 1 SF4 helicase domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000113195.
KOiK02314.
OMAiGAMLRDN.

Family and domain databases

CDDicd00984. DnaB_C. 1 hit.
Gene3Di1.10.860.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR007692. DNA_helicase_DnaB.
IPR007694. DNA_helicase_DnaB-like_C.
IPR007693. DNA_helicase_DnaB-like_N.
IPR016136. DNA_helicase_N/primase_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00772. DnaB. 1 hit.
PF03796. DnaB_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF48024. SSF48024. 1 hit.
SSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00665. DnaB. 1 hit.
PROSITEiPS51199. SF4_HELICASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q57ER7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEAAVRKLD DARDQKDVRY REAPHNIEAE QALLGAILIN NDAFYRVSDF
60 70 80 90 100
LKPTHFLEPL HRRIYEIATD LIRVGKMANP VTMKTFLPTE GKVGDLSIFQ
110 120 130 140 150
YVTRLATEAV TIINAEDYGR AIYDLATRRA LIGIGEDMVN IAYDAPVDMA
160 170 180 190 200
PQEQIEDAER RLFELAETGR YDGGFLPFKD AVTTAVDMAN AAFMRDGHLS
210 220 230 240 250
GISTGIHALD SKMGGLQPSD LIILAGRPGM GKTSLATNIA FNIANAYEPD
260 270 280 290 300
QQADGTIKAA NGGVVGFFSL EMSAEQLATR IISEQTEVSS SKIRRGEITE
310 320 330 340 350
TDFEKLVACS QVMQKIPLYI DQTGGISIAQ LAARARRLKR QRGLDVLVID
360 370 380 390 400
YVQLMTGSSK ASAQNRVQEI TEITTGLKAL AKELNVPIIA LSQLSRQVES
410 420 430 440 450
RDDKRPQLSD LRESGSIEQD ADVVLFVFRE EYYVKNLEPR DKFDPKYEEW
460 470 480 490 500
KQHFEKVRGT ADVIIAKQRH GPTGTVKLAF QSEFTRFADL ADGSYLPEQY

E
Length:501
Mass (Da):55,737
Last modified:May 10, 2005 - v1
Checksum:iCFE77DA9536E68B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017223 Genomic DNA. Translation: AAX73867.1.
RefSeqiWP_002963606.1. NC_006932.1.

Genome annotation databases

EnsemblBacteriaiAAX73867; AAX73867; BruAb1_0472.
GeneIDi3787224.
KEGGibmb:BruAb1_0472.
PATRICi17822524. VBIBruAbo15061_0499.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017223 Genomic DNA. Translation: AAX73867.1.
RefSeqiWP_002963606.1. NC_006932.1.

3D structure databases

ProteinModelPortaliQ57ER7.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAX73867; AAX73867; BruAb1_0472.
GeneIDi3787224.
KEGGibmb:BruAb1_0472.
PATRICi17822524. VBIBruAbo15061_0499.

Phylogenomic databases

HOGENOMiHOG000113195.
KOiK02314.
OMAiGAMLRDN.

Family and domain databases

CDDicd00984. DnaB_C. 1 hit.
Gene3Di1.10.860.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR007692. DNA_helicase_DnaB.
IPR007694. DNA_helicase_DnaB-like_C.
IPR007693. DNA_helicase_DnaB-like_N.
IPR016136. DNA_helicase_N/primase_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00772. DnaB. 1 hit.
PF03796. DnaB_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF48024. SSF48024. 1 hit.
SSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00665. DnaB. 1 hit.
PROSITEiPS51199. SF4_HELICASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ57ER7_BRUAB
AccessioniPrimary (citable) accession number: Q57ER7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 2, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.