Reviewed, UniProtKB/Swiss-Prot Q57EL6 (ALLA_BRUAB)

Names and origin

Protein names

Recommended name:
    Ureidoglycolate hydrolase
    EC=3.5.3.19

Gene names

Name:	allA
Ordered Locus Names:	BruAb1_0529

Organism

Brucella abortus [Complete proteome] [HAMAP]

Taxonomic identifier

235 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	169 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP MF_00616
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP MF_00616
Subunit structure	Homodimer By similarity. HAMAP MF_00616
Sequence similarities	Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	allantoin catabolic process Inferred from electronic annotation. Source: InterPro purine base catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ureidoglycolate hydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 169	169	Ureidoglycolate hydrolase HAMAP MF_00616		PRO_1000061345

Sequences

	Sequence		Length	Mass (Da)
	Q57EL6-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 9D42DFA9E69C3EDB	FASTA	169	19,043
	10 20 30 40 50 60 MQIETLTVEP LTKEAFAPFG DVIEVEGAQL RLINNGTTER YHDLARMEAA GTQTRVLINI 70 80 90 100 110 120 FRGQSFAAPI DIMMMERHPF GSQAFIPLNG RPFLVVVAED AGAGPARPRA FLARGDQGVN 130 140 150 160 YLRNIWHHPL LALEQKSDFL VVDRAGREDN LEEYFFSDYA YRIETTQTA

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941 / Biovar 1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017223 Genomic DNA. Translation: AAX73918.1.
RefSeq	YP_221279.1.
3D structure databases
HSSP	HSSP built from PDB template 2BDR based on UniProtKB P59285.
SMR	Q57EL6. Positions 4-159.
ModBase	Search...
Genome annotation databases
GeneID	3339958.
GenomeReviews	Gene locus BruAb1_0529 in contig AE017223_GR.
KEGG	bmb:BruAb1_0529.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289179.
OMA	MRFHRLA.
PhylomeDB	Q57EL6.
Enzyme and pathway databases
BioCyc	BABO262698:BRUAB1_0529-MONOMER.
BRENDA	3.5.3.19. 575.
Family and domain databases
HAMAP	MF_00616. Ureidogly_hydro. [Tree]
InterPro	IPR007247. Ureidogly_hydro. [Graphical view]
PANTHER	PTHR21221. Ureidogly_hydro. 1 hit.
Pfam	PF04115. Ureidogly_hydro. 1 hit. [Graphical view]
PIRSF	PIRSF017306. Ureidogly_hydro. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLA_BRUAB

Accession

Primary (citable) accession number: Q57EL6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	May 10, 2005
Last modified:	January 19, 2010
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)