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Q57EI4 (XYLA_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Xylose isomerase
EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:BruAb1_0569
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella ›

Protein attributes

Sequence length435 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP-Rule MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP-Rule MF_00455

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00455

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 435435Xylose isomerase HAMAP-Rule MF_00455
PRO_0000236958

Sites

Active site1001 By similarity
Active site1031 By similarity
Metal binding2311Magnesium 1 By similarity
Metal binding2671Magnesium 1 By similarity
Metal binding2671Magnesium 2 By similarity
Metal binding2701Magnesium 2 By similarity
Metal binding2951Magnesium 1 By similarity
Metal binding3061Magnesium 2 By similarity
Metal binding3081Magnesium 2 By similarity
Metal binding3381Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q57EI4 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 5C5A95ECE415E6E2

FASTA43549,004
        10         20         30         40         50         60 
MSTGFFGDIQ KVRYEGPESD NPLAFRHYNA DEIVLGKRME DHLRFAVAYW HSFAWEGGDP 

        70         80         90        100        110        120 
FGGRTFDRPW FSNEIDAAKL KADVAFEFFS LLGAPYYCFH DADVRPEGRN FAENTRYLNE 

       130        140        150        160        170        180 
IVDIFEKKQA ETGMKLLWGT ANLFSNRRYM AGAATNPDPD VFAFAAATVK TCIDATKRLG 

       190        200        210        220        230        240 
GENYVLWGGR EGYETLLNTD LSRELDHMGR FLSLVVEYKH KIGFKGTILI EPKPQEPTKH 

       250        260        270        280        290        300 
QYDYDVATVY GFLKRYGLEN EVKVNIEQGH AILAGHSFEH ELALARTLGI FGSIDMNRND 

       310        320        330        340        350        360 
YQSGWDTDQF PNNVPEMALA YYQVLLAGGF TTGGTNFDAK LRRQSLDPQD LLIGHIGGMD 

       370        380        390        400        410        420 
CCARGLKAAA RMLEDGALSK PLDERYAGWN GEFGKRLLSG LSLDQIAGEV EAKDINPQPK 

       430 
SGRQEYLENI VNRYV

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017223 Genomic DNA. Translation: AAX73950.1.
RefSeqYP_221311.1. NC_006932.1.

3D structure databases

ProteinModelPortalQ57EI4.
SMRQ57EI4. Positions 4-435.
ModBaseSearch...

Protein-protein interaction databases

STRING262698.BruAb1_0569.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX73950; AAX73950; BruAb1_0569.
GeneID3339857.
KEGGbmb:BruAb1_0569.
PATRIC17822727. VBIBruAbo15061_0600.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2115.
HOGENOMHOG000252293.
KOK01805.
OMAHTFQHEL.
ProtClustDBPRK05474.

Enzyme and pathway databases

BioCycBABO262698:GJC2-575-MONOMER.

Family and domain databases

Gene3D3.20.20.150. 1 hit.
HAMAPMF_00455. Xylose_isom_A.
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_BRUAB
AccessionPrimary (citable) accession number: Q57EI4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: May 10, 2005
Last modified: May 1, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names

SIMILARITY comments

Index of protein domains and families

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