Reviewed,
UniProtKB/Swiss-Prot Q57EI0 (BETB_BRUAB)
Last modified
February 9, 2010.
Version 33.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Betaine aldehyde dehydrogenase Short name=BADH EC=1.2.1.8 | ||||
| Gene names |
| ||||
| Organism | Brucella abortus [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 235 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella |
Protein attributes
| Sequence length | 487 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP MF_00804 |
| Pathway | Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP MF_00804 |
| Sequence similarities | Belongs to the aldehyde dehydrogenase family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: HAMAP oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | betaine-aldehyde dehydrogenase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 487 | 487 | Betaine aldehyde dehydrogenase HAMAP MF_00804 | PRO_0000056536 | |||||
Regions | |||||||||
| Nucleotide binding | 227 – 232 | 6 | NAD By similarity | ||||||
Sites | |||||||||
| Active site | 249 | 1 | By similarity | ||||||
| Active site | 283 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941 / Biovar 1. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE017223 Genomic DNA. Translation: AAX73954.1. |
| RefSeq | YP_221315.1. |
3D structure databases | |
| SMR | Q57EI0. Positions 7-487. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3339662. |
| GenomeReviews | Gene locus BruAb1_0574 in contig AE017223_GR. |
| KEGG | bmb:BruAb1_0574. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG752218. |
| OMA | MLIGDPL. |
| PhylomeDB | Q57EI0. |
Enzyme and pathway databases | |
| BioCyc | BABO262698:BRUAB1_0574-MONOMER. |
| BRENDA | 1.2.1.8. 575. |
Family and domain databases | |
| HAMAP | MF_00804. BADH. [Tree] |
| InterPro | IPR016161. Ald_DH/histidinol_DH. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH. IPR011264. Betaine_Ald_DH. [Graphical view] |
| Gene3D | G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit. |
| PANTHER | PTHR11699. Aldehyde_dehyd. 1 hit. |
| Pfam | PF00171. Aldedh. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01804. BADH. 1 hit. |
| PROSITE | PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BETB_BRUAB | ||||||||
| Accession | Primary (citable) accession number: Q57EI0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Brucella abortus strain 9-941 Brucella abortus (strain 9-941): entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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