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Q57EH9 (BETI_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
HTH-type transcriptional regulator BetI
Gene names
Name:betI
Ordered Locus Names:BruAb1_0576
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine By similarity. HAMAP-Rule MF_00768

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway [regulation]. HAMAP-Rule MF_00768

Sequence similarities

Contains 1 HTH tetR-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198HTH-type transcriptional regulator BetI HAMAP-Rule MF_00768
PRO_0000257726

Regions

Domain8 – 6861HTH tetR-type
DNA binding31 – 5020H-T-H motif By similarity

Sequences

Sequence LengthMass (Da)Tools
Q57EH9 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 4C8AEC3346CA6337

FASTA19821,678
        10         20         30         40         50         60 
MPKIGMEPLR RRELIDAAIR TIGQRGSLDV TVAQIAHEAG VSPALAHHYF GGKDKLILAT 

        70         80         90        100        110        120 
MRHLLRELGR DLNVAIKQAN TPHERIAAII AVNFSATQFA QETIAAWLTF YVHAQQSDDI 

       130        140        150        160        170        180 
KRLLRIYARR LHSNLVFALE QLTSRARANR IAEGAGAMID GLYIRHALGA DAPDAASAIA 

       190 
LVEDYIAIQL SGQPSAEN 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017223 Genomic DNA. Translation: AAX73955.1.
RefSeqYP_221316.1. NC_006932.1.

3D structure databases

ProteinModelPortalQ57EH9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262698.BruAb1_0576.

Proteomic databases

PRIDEQ57EH9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX73955; AAX73955; BruAb1_0576.
GeneID3341143.
KEGGbmb:BruAb1_0576.
PATRIC17822741. VBIBruAbo15061_0607.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1309.
HOGENOMHOG000248227.
KOK02167.
OMALIDGLYI.
OrthoDBEOG6FFS5N.

Enzyme and pathway databases

BioCycBABO262698:GJC2-582-MONOMER.
UniPathwayUPA00529.

Family and domain databases

Gene3D1.10.357.10. 1 hit.
HAMAPMF_00768. HTH_type_BetI.
InterProIPR023772. DNA-bd_HTH_TetR-type_CS.
IPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
IPR017757. Tscrpt_rep_BetI.
[Graphical view]
PfamPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSPR00455. HTHTETR.
SUPFAMSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
TIGRFAMsTIGR03384. betaine_BetI. 1 hit.
PROSITEPS01081. HTH_TETR_1. 1 hit.
PS50977. HTH_TETR_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETI_BRUAB
AccessionPrimary (citable) accession number: Q57EH9
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 10, 2005
Last modified: May 14, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names