Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q57EH9

- BETI_BRUAB

UniProt

Q57EH9 - BETI_BRUAB

Protein

HTH-type transcriptional regulator BetI

Gene

betI

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine By similarity.By similarity

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi31 – 5020H-T-H motifUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-HAMAP
    2. sequence-specific DNA binding transcription factor activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycine betaine biosynthetic process from choline Source: UniProtKB-HAMAP
    2. negative regulation of transcription, DNA-templated Source: UniProtKB-HAMAP
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Repressor

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciBABO262698:GJC2-582-MONOMER.
    UniPathwayiUPA00529.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    HTH-type transcriptional regulator BetIUniRule annotation
    Gene namesi
    Name:betIUniRule annotation
    Ordered Locus Names:BruAb1_0576
    OrganismiBrucella abortus biovar 1 (strain 9-941)
    Taxonomic identifieri262698 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000540: Chromosome I

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 198198HTH-type transcriptional regulator BetIPRO_0000257726Add
    BLAST

    Proteomic databases

    PRIDEiQ57EH9.

    Interactioni

    Protein-protein interaction databases

    STRINGi262698.BruAb1_0576.

    Structurei

    3D structure databases

    ProteinModelPortaliQ57EH9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini8 – 6861HTH tetR-typeUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 HTH tetR-type DNA-binding domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1309.
    HOGENOMiHOG000248227.
    KOiK02167.
    OMAiLIDGLYI.
    OrthoDBiEOG6FFS5N.

    Family and domain databases

    Gene3Di1.10.357.10. 1 hit.
    HAMAPiMF_00768. HTH_type_BetI.
    InterProiIPR023772. DNA-bd_HTH_TetR-type_CS.
    IPR009057. Homeodomain-like.
    IPR001647. HTH_TetR.
    IPR015893. Tet_transcr_reg_TetR-like_C.
    IPR011075. Tet_transcr_reg_TetR-rel_C.
    IPR017757. Tscrpt_rep_BetI.
    [Graphical view]
    PfamiPF00440. TetR_N. 1 hit.
    [Graphical view]
    PRINTSiPR00455. HTHTETR.
    SUPFAMiSSF46689. SSF46689. 1 hit.
    SSF48498. SSF48498. 1 hit.
    TIGRFAMsiTIGR03384. betaine_BetI. 1 hit.
    PROSITEiPS01081. HTH_TETR_1. 1 hit.
    PS50977. HTH_TETR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q57EH9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPKIGMEPLR RRELIDAAIR TIGQRGSLDV TVAQIAHEAG VSPALAHHYF    50
    GGKDKLILAT MRHLLRELGR DLNVAIKQAN TPHERIAAII AVNFSATQFA 100
    QETIAAWLTF YVHAQQSDDI KRLLRIYARR LHSNLVFALE QLTSRARANR 150
    IAEGAGAMID GLYIRHALGA DAPDAASAIA LVEDYIAIQL SGQPSAEN 198
    Length:198
    Mass (Da):21,678
    Last modified:May 10, 2005 - v1
    Checksum:i4C8AEC3346CA6337
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX73955.1.
    RefSeqiYP_221316.1. NC_006932.1.

    Genome annotation databases

    EnsemblBacteriaiAAX73955; AAX73955; BruAb1_0576.
    GeneIDi3341143.
    KEGGibmb:BruAb1_0576.
    PATRICi17822741. VBIBruAbo15061_0607.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX73955.1 .
    RefSeqi YP_221316.1. NC_006932.1.

    3D structure databases

    ProteinModelPortali Q57EH9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262698.BruAb1_0576.

    Proteomic databases

    PRIDEi Q57EH9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAX73955 ; AAX73955 ; BruAb1_0576 .
    GeneIDi 3341143.
    KEGGi bmb:BruAb1_0576.
    PATRICi 17822741. VBIBruAbo15061_0607.

    Phylogenomic databases

    eggNOGi COG1309.
    HOGENOMi HOG000248227.
    KOi K02167.
    OMAi LIDGLYI.
    OrthoDBi EOG6FFS5N.

    Enzyme and pathway databases

    UniPathwayi UPA00529 .
    BioCyci BABO262698:GJC2-582-MONOMER.

    Family and domain databases

    Gene3Di 1.10.357.10. 1 hit.
    HAMAPi MF_00768. HTH_type_BetI.
    InterProi IPR023772. DNA-bd_HTH_TetR-type_CS.
    IPR009057. Homeodomain-like.
    IPR001647. HTH_TetR.
    IPR015893. Tet_transcr_reg_TetR-like_C.
    IPR011075. Tet_transcr_reg_TetR-rel_C.
    IPR017757. Tscrpt_rep_BetI.
    [Graphical view ]
    Pfami PF00440. TetR_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00455. HTHTETR.
    SUPFAMi SSF46689. SSF46689. 1 hit.
    SSF48498. SSF48498. 1 hit.
    TIGRFAMsi TIGR03384. betaine_BetI. 1 hit.
    PROSITEi PS01081. HTH_TETR_1. 1 hit.
    PS50977. HTH_TETR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
      Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
      J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 9-941.

    Entry informationi

    Entry nameiBETI_BRUAB
    AccessioniPrimary (citable) accession number: Q57EH9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella abortus strain 9-941
      Brucella abortus (strain 9-941): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3