Q57DS5 (RS4_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S4

Gene names

Name:	rpsD
Ordered Locus Names:	BruAb1_0843

Organism

Brucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]

Taxonomic identifier

262698 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus › Brucella abortus bv. 1

Protein attributes

Sequence length	205 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit By similarity. HAMAP-Rule MF_01306 With S5 and S12 plays an important role in translational accuracy By similarity. HAMAP-Rule MF_01306
Subunit structure	Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.
Sequence similarities	Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 205	205	30S ribosomal protein S4 HAMAP-Rule MF_01306		PRO_0000228879
Regions
	Domain	94 – 157	64	S4 RNA-binding

Sequences

	Sequence		Length	Mass (Da)
	Q57DS5 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: FC76E7BF0F4A83E1	FASTA	205	23,566
	10 20 30 40 50 60 MSKRESAKHK IDRRLGENIW GRPKSPVNRR EYGPGQHGQR RKGKLSDFGV QLRAKQKLKG 70 80 90 100 110 120 FYGDISEKQF RKTYEEAARR KGDTGENLIG LLESRLDAVV YRAKFVPTIF AARQFINHGH 130 140 150 160 170 180 VNVNGRRVNI QSYRLKVGDV VEVREKSKQL AIVLEAVQLA ERDVPDYIDV DHNKMVATYN 190 200 RVPGLSDVPY AVQMEPNLVV EFYSR

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017223 Genomic DNA. Translation: AAX74209.1.
RefSeq	YP_221570.1. NC_006932.1.
3D structure databases
ProteinModelPortal	Q57DS5.
ModBase	Search...
Protein-protein interaction databases
STRING	262698.BruAb1_0843.
Proteomic databases
PRIDE	Q57DS5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAX74209; AAX74209; BruAb1_0843.
GeneID	3340473.
KEGG	bmb:BruAb1_0843.
PATRIC	17823316. VBIBruAbo15061_0889.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0522.
HOGENOM	HOG000221004.
KO	K02986.
OMA	YRCKPGD.
ProtClustDB	PRK05327.
Enzyme and pathway databases
BioCyc	BABO262698:GJC2-855-MONOMER.
Family and domain databases
Gene3D	1.10.1050.10. 1 hit. 3.10.290.10. 1 hit.
HAMAP	MF_01306_B. Ribosomal_S4_B.
InterPro	IPR022801. Ribosomal_S4/S9. IPR001912. Ribosomal_S4/S9_N. IPR005709. Ribosomal_S4_bac-type. IPR018079. Ribosomal_S4_CS. IPR002942. S4_RNA-bd. [Graphical view]
PANTHER	PTHR11831. PTHR11831. 1 hit.
Pfam	PF00163. Ribosomal_S4. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
TIGRFAMs	TIGR01017. rpsD_bact. 1 hit.
PROSITE	PS00632. RIBOSOMAL_S4. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS4_BRUAB

Accession

Primary (citable) accession number: Q57DS5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 21, 2006
Last sequence update:	May 10, 2005
Last modified:	May 1, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program