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Q57DI4

- ANMK_BRUAB

UniProt

Q57DI4 - ANMK_BRUAB

Protein

Anhydro-N-acetylmuramic acid kinase

Gene

anmK

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
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    Functioni

    Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.UniRule annotation

    Catalytic activityi

    ATP + 1,6-anhydro-N-acetyl-beta-muramate + H2O = ADP + N-acetylmuramate 6-phosphate.UniRule annotation

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi13 – 208ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. kinase activity Source: UniProtKB-KW
    3. phosphotransferase activity, alcohol group as acceptor Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 1,6-anhydro-N-acetyl-beta-muramic acid catabolic process Source: UniProtKB-UniPathway
    2. amino sugar metabolic process Source: UniProtKB-HAMAP
    3. carbohydrate metabolic process Source: UniProtKB-KW
    4. peptidoglycan turnover Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Carbohydrate metabolism

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBABO262698:GJC2-950-MONOMER.
    UniPathwayiUPA00343.
    UPA00544.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Anhydro-N-acetylmuramic acid kinaseUniRule annotation (EC:2.7.1.170UniRule annotation)
    Alternative name(s):
    AnhMurNAc kinaseUniRule annotation
    Gene namesi
    Name:anmKUniRule annotation
    Ordered Locus Names:BruAb1_0936
    OrganismiBrucella abortus biovar 1 (strain 9-941)
    Taxonomic identifieri262698 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000540: Chromosome I

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 373373Anhydro-N-acetylmuramic acid kinasePRO_0000249980Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi262698.BruAb1_0936.

    Structurei

    3D structure databases

    ProteinModelPortaliQ57DI4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the anhydro-N-acetylmuramic acid kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2377.
    HOGENOMiHOG000256308.
    KOiK09001.
    OMAiRPVVWDF.
    OrthoDBiEOG64N9WW.

    Family and domain databases

    HAMAPiMF_01270. AnhMurNAc_kinase.
    InterProiIPR005338. Anhydro_N_Ac-Mur_kinase.
    [Graphical view]
    PfamiPF03702. UPF0075. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q57DI4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPDLKRAIGL MSGTSMDGID IALLATDGEN WIERRASASM DYSDGFRARL    50
    KAGLVDARAI KDRAERPGLL RQLEHDLTLL HAVAVHDFLH EQGLQPHEID 100
    VIGFHGQTVL HRPNESLTVQ IGDGALLARE TGIPVVYDMR AEDMRHGGQG 150
    APLIPAYHAA LAANLPLGLK GPVVFVNIGG ISNLTYVGED GALIAYDSGP 200
    GNMLIDQWME LHGHGRFDPG GATAMSGSVD RNTAHRYLEH EFFKGNHRRS 250
    LDRGDFAIPA KGELNLADGA RTLAFVSAAA ILKSASHLPA RPRTYVVSGG 300
    GRKNGALMDE LTALAEREGA HVIDADNAGF DGDAMEAEAW AYLAVRSLCG 350
    LPLTYPSTTG CDKPVSGGVP VRP 373
    Length:373
    Mass (Da):39,828
    Last modified:May 10, 2005 - v1
    Checksum:iF12C16EFF7C8773F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX74300.1.
    RefSeqiYP_221661.1. NC_006932.1.

    Genome annotation databases

    EnsemblBacteriaiAAX74300; AAX74300; BruAb1_0936.
    GeneIDi3340124.
    KEGGibmb:BruAb1_0936.
    PATRICi17823510. VBIBruAbo15061_0985.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX74300.1 .
    RefSeqi YP_221661.1. NC_006932.1.

    3D structure databases

    ProteinModelPortali Q57DI4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262698.BruAb1_0936.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAX74300 ; AAX74300 ; BruAb1_0936 .
    GeneIDi 3340124.
    KEGGi bmb:BruAb1_0936.
    PATRICi 17823510. VBIBruAbo15061_0985.

    Phylogenomic databases

    eggNOGi COG2377.
    HOGENOMi HOG000256308.
    KOi K09001.
    OMAi RPVVWDF.
    OrthoDBi EOG64N9WW.

    Enzyme and pathway databases

    UniPathwayi UPA00343 .
    UPA00544 .
    BioCyci BABO262698:GJC2-950-MONOMER.

    Family and domain databases

    HAMAPi MF_01270. AnhMurNAc_kinase.
    InterProi IPR005338. Anhydro_N_Ac-Mur_kinase.
    [Graphical view ]
    Pfami PF03702. UPF0075. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
      Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
      J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 9-941.

    Entry informationi

    Entry nameiANMK_BRUAB
    AccessioniPrimary (citable) accession number: Q57DI4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 19, 2006
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella abortus strain 9-941
      Brucella abortus (strain 9-941): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3