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Q57DI4 (ANMK_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Anhydro-N-acetylmuramic acid kinase

EC=2.7.1.170
Alternative name(s):
AnhMurNAc kinase
Gene names
Name:anmK
Ordered Locus Names:BruAb1_0936
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling By similarity. HAMAP-Rule MF_01270

Catalytic activity

ATP + 1,6-anhydro-N-acetyl-beta-muramate + H2O = ADP + N-acetylmuramate 6-phosphate. HAMAP-Rule MF_01270

Pathway

Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation. HAMAP-Rule MF_01270

Cell wall biogenesis; peptidoglycan recycling. HAMAP-Rule MF_01270

Sequence similarities

Belongs to the anhydro-N-acetylmuramic acid kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 373373Anhydro-N-acetylmuramic acid kinase HAMAP-Rule MF_01270
PRO_0000249980

Regions

Nucleotide binding13 – 208ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q57DI4 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: F12C16EFF7C8773F

FASTA37339,828
        10         20         30         40         50         60 
MPDLKRAIGL MSGTSMDGID IALLATDGEN WIERRASASM DYSDGFRARL KAGLVDARAI 

        70         80         90        100        110        120 
KDRAERPGLL RQLEHDLTLL HAVAVHDFLH EQGLQPHEID VIGFHGQTVL HRPNESLTVQ 

       130        140        150        160        170        180 
IGDGALLARE TGIPVVYDMR AEDMRHGGQG APLIPAYHAA LAANLPLGLK GPVVFVNIGG 

       190        200        210        220        230        240 
ISNLTYVGED GALIAYDSGP GNMLIDQWME LHGHGRFDPG GATAMSGSVD RNTAHRYLEH 

       250        260        270        280        290        300 
EFFKGNHRRS LDRGDFAIPA KGELNLADGA RTLAFVSAAA ILKSASHLPA RPRTYVVSGG 

       310        320        330        340        350        360 
GRKNGALMDE LTALAEREGA HVIDADNAGF DGDAMEAEAW AYLAVRSLCG LPLTYPSTTG 

       370 
CDKPVSGGVP VRP 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017223 Genomic DNA. Translation: AAX74300.1.
RefSeqYP_221661.1. NC_006932.1.

3D structure databases

ProteinModelPortalQ57DI4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262698.BruAb1_0936.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX74300; AAX74300; BruAb1_0936.
GeneID3340124.
KEGGbmb:BruAb1_0936.
PATRIC17823510. VBIBruAbo15061_0985.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2377.
HOGENOMHOG000256308.
KOK09001.
OMARPVVWDF.
OrthoDBEOG64N9WW.

Enzyme and pathway databases

BioCycBABO262698:GJC2-950-MONOMER.
UniPathwayUPA00343.
UPA00544.

Family and domain databases

HAMAPMF_01270. AnhMurNAc_kinase.
InterProIPR005338. Anhydro_N_Ac-Mur_kinase.
[Graphical view]
PfamPF03702. UPF0075. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameANMK_BRUAB
AccessionPrimary (citable) accession number: Q57DI4
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: May 10, 2005
Last modified: May 14, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names