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Q57CS0

- RL5_BRUAB

UniProt

Q57CS0 - RL5_BRUAB

Protein

50S ribosomal protein L5

Gene

rplE

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
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    Functioni

    This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.UniRule annotation

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro
    3. tRNA binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding, tRNA-binding

    Enzyme and pathway databases

    BioCyciBABO262698:GJC2-1248-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L5UniRule annotation
    Gene namesi
    Name:rplEUniRule annotation
    Ordered Locus Names:BruAb1_1226
    OrganismiBrucella abortus biovar 1 (strain 9-941)
    Taxonomic identifieri262698 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000540: Chromosome I

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 18518550S ribosomal protein L5PRO_0000242976Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

    Protein-protein interaction databases

    STRINGi262698.BruAb1_1226.

    Structurei

    3D structure databases

    ProteinModelPortaliQ57CS0.
    SMRiQ57CS0. Positions 8-185.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L5P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0094.
    HOGENOMiHOG000231311.
    KOiK02931.
    OMAiFNMPFNS.
    OrthoDBiEOG6M9F1R.

    Family and domain databases

    Gene3Di3.30.1440.10. 1 hit.
    HAMAPiMF_01333_B. Ribosomal_L5_B.
    InterProiIPR002132. Ribosomal_L5.
    IPR020930. Ribosomal_L5_bac-type.
    IPR020929. Ribosomal_L5_CS.
    IPR022803. Ribosomal_L5_domain.
    [Graphical view]
    PANTHERiPTHR11994. PTHR11994. 1 hit.
    PfamiPF00281. Ribosomal_L5. 1 hit.
    PF00673. Ribosomal_L5_C. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002161. Ribosomal_L5. 1 hit.
    SUPFAMiSSF55282. SSF55282. 1 hit.
    PROSITEiPS00358. RIBOSOMAL_L5. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q57CS0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEAKALPRF KKLYQDNIRK ALLEEFKYDN EMQIPRITKV VLNMGVGEAT    50
    GDSKKPAVAA EDLAMIAGQK AVVTRARNSI ATFKLREGMP IGAKVTLRQD 100
    RMYEFLDRLI TIALPRVRDF RGLNPKSFDG RGNYAMGIKE HIVFPEINYD 150
    KVDQIWGMDI IVCTTAKTDD EARSLLRAFN FPFRQ 185
    Length:185
    Mass (Da):21,074
    Last modified:May 10, 2005 - v1
    Checksum:i22059A13FB6BDF5A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX74564.1.
    RefSeqiYP_221925.1. NC_006932.1.

    Genome annotation databases

    EnsemblBacteriaiAAX74564; AAX74564; BruAb1_1226.
    GeneIDi3340120.
    KEGGibmb:BruAb1_1226.
    PATRICi17824144. VBIBruAbo15061_1294.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX74564.1 .
    RefSeqi YP_221925.1. NC_006932.1.

    3D structure databases

    ProteinModelPortali Q57CS0.
    SMRi Q57CS0. Positions 8-185.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262698.BruAb1_1226.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAX74564 ; AAX74564 ; BruAb1_1226 .
    GeneIDi 3340120.
    KEGGi bmb:BruAb1_1226.
    PATRICi 17824144. VBIBruAbo15061_1294.

    Phylogenomic databases

    eggNOGi COG0094.
    HOGENOMi HOG000231311.
    KOi K02931.
    OMAi FNMPFNS.
    OrthoDBi EOG6M9F1R.

    Enzyme and pathway databases

    BioCyci BABO262698:GJC2-1248-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1440.10. 1 hit.
    HAMAPi MF_01333_B. Ribosomal_L5_B.
    InterProi IPR002132. Ribosomal_L5.
    IPR020930. Ribosomal_L5_bac-type.
    IPR020929. Ribosomal_L5_CS.
    IPR022803. Ribosomal_L5_domain.
    [Graphical view ]
    PANTHERi PTHR11994. PTHR11994. 1 hit.
    Pfami PF00281. Ribosomal_L5. 1 hit.
    PF00673. Ribosomal_L5_C. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002161. Ribosomal_L5. 1 hit.
    SUPFAMi SSF55282. SSF55282. 1 hit.
    PROSITEi PS00358. RIBOSOMAL_L5. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
      Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
      J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 9-941.

    Entry informationi

    Entry nameiRL5_BRUAB
    AccessioniPrimary (citable) accession number: Q57CS0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 27, 2006
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella abortus strain 9-941
      Brucella abortus (strain 9-941): entries and gene names
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3