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Q57CR3 (RL22_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L22
Gene names
Name:rplV
Ordered Locus Names:BruAb1_1233
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length129 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity. HAMAP-Rule MF_01331

The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome By similarity. HAMAP-Rule MF_01331

Subunit structure

Part of the 50S ribosomal subunit By similarity. HAMAP-Rule MF_01331

Sequence similarities

Belongs to the ribosomal protein L22P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentlarge ribosomal subunit

Inferred from electronic annotation. Source: InterPro

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 12912950S ribosomal protein L22 HAMAP-Rule MF_01331
PRO_0000243128

Sequences

Sequence LengthMass (Da)Tools
Q57CR3 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 937A62872927C7CA

FASTA12914,143
        10         20         30         40         50         60 
MGKAKAPRQL KDNEAKAVAR TLRVSPQKLN LVASMIRGKK VNAALADLTF SRKRIAGTVK 

        70         80         90        100        110        120 
KTLESAIANA ENNHDLDVDA LIVAEAYVGK SIVMKRFHVR DRGRASRIEK PFSHLTIVVR 


EVAEKGKAA 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017223 Genomic DNA. Translation: AAX74571.1.
RefSeqYP_221932.1. NC_006932.1.

3D structure databases

ProteinModelPortalQ57CR3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262698.BruAb1_1233.

Proteomic databases

PRIDEQ57CR3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX74571; AAX74571; BruAb1_1233.
GeneID3341104.
KEGGbmb:BruAb1_1233.
PATRIC17824158. VBIBruAbo15061_1301.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0091.
HOGENOMHOG000205046.
KOK02890.
OMAGRAFRIN.
OrthoDBEOG6V4GKB.
ProtClustDBPRK00565.

Enzyme and pathway databases

BioCycBABO262698:GJC2-1255-MONOMER.

Family and domain databases

Gene3D3.90.470.10. 1 hit.
HAMAPMF_01331_B. Ribosomal_L22_B.
InterProIPR001063. Ribosomal_L22.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view]
PANTHERPTHR13501. PTHR13501. 1 hit.
PfamPF00237. Ribosomal_L22. 1 hit.
[Graphical view]
SUPFAMSSF54843. SSF54843. 1 hit.
TIGRFAMsTIGR01044. rplV_bact. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRL22_BRUAB
AccessionPrimary (citable) accession number: Q57CR3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: May 10, 2005
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names