Q57CP5 (RL1_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L1

Gene names

Name:	rplA
Ordered Locus Names:	BruAb1_1251

Organism

Brucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]

Taxonomic identifier

262698 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus › Brucella abortus bv. 1

Protein attributes

Sequence length	233 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release By similarity. HAMAP-Rule MF_01318 Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA By similarity. HAMAP-Rule MF_01318
Subunit structure	Part of the 50S ribosomal subunit By similarity.
Sequence similarities	Belongs to the ribosomal protein L1P family.

Ontologies

Keywords
Biological process	Translation regulation
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Repressor Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of translation Inferred from electronic annotation. Source: UniProtKB-KW translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 233	233	50S ribosomal protein L1 HAMAP-Rule MF_01318		PRO_0000230593

Sequences

	Sequence		Length	Mass (Da)
	Q57CP5 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 3E14C01670D71596	FASTA	233	24,611
	10 20 30 40 50 60 MAKISKRINK IREGVDRNKL YDLSAAIGLV KERAVAKFDE TVEIAMNLGV DPRHADQMVR 70 80 90 100 110 120 GVVNLPNGTG RTVRVAVFAR GDKAEEAKKA GADIVGAEEL FEIVNGGKIE FDRCIATPDM 130 140 150 160 170 180 MPLVGRLGKV LGPRGMMPNP KVGTVTTDVA AAVAASKGGA VEFRVEKAGI IHAGIGKVSF 190 200 210 220 230 DNAKLEENIK AFADAVIKAK PSAAKGEYVK RVSISSTMGV GVKVDPSTVK VVD

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017223 Genomic DNA. Translation: AAX74589.1.
RefSeq	YP_221950.1. NC_006932.1.
3D structure databases
ProteinModelPortal	Q57CP5.
SMR	Q57CP5. Positions 6-227.
ModBase	Search...
Protein-protein interaction databases
STRING	262698.BruAb1_1251.
Proteomic databases
PRIDE	Q57CP5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAX74589; AAX74589; BruAb1_1251.
GeneID	3340093.
KEGG	bmb:BruAb1_1251.
PATRIC	17824194. VBIBruAbo15061_1319.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0081.
HOGENOM	HOG000207015.
KO	K02863.
OMA	AKGRYVK.
ProtClustDB	PRK05424.
Enzyme and pathway databases
BioCyc	BABO262698:GJC2-1273-MONOMER.
Family and domain databases
Gene3D	3.30.190.20. 2 hits. 3.40.50.790. 1 hit.
HAMAP	MF_01318_B. Ribosomal_L1_B.
InterPro	IPR005878. Ribosom_L1_bac-type. IPR002143. Ribosomal_L1. IPR016094. Ribosomal_L1_2-a/b-sand. IPR016095. Ribosomal_L1_3-a/b-sand. IPR023673. Ribosomal_L1_CS. IPR023674. Ribosomal_L1_SF. [Graphical view]
Pfam	PF00687. Ribosomal_L1. 1 hit. [Graphical view]
PIRSF	PIRSF002155. Ribosomal_L1. 1 hit.
SUPFAM	SSF56808. Ribosomal_L1. 1 hit.
TIGRFAMs	TIGR01169. rplA_bact. 1 hit.
PROSITE	PS01199. RIBOSOMAL_L1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL1_BRUAB

Accession

Primary (citable) accession number: Q57CP5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	May 10, 2005
Last modified:	May 1, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program