Q57CF0 (URE32_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease subunit gamma 2
EC=3.5.1.5

Alternative name(s):
Urea amidohydrolase subunit gamma 2

Gene names

Name:	ureA2
Synonyms:	ureA, ureA-2
Ordered Locus Names:	BruAb1_1353

Organism

Brucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]

Taxonomic identifier

262698 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus › Brucella abortus bv. 1

Protein attributes

Sequence length	100 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Urea + H2O = CO2 + 2 NH3. HAMAP-Rule MF_00739
Pathway	Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. HAMAP-Rule MF_00739
Subunit structure	Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the urease gamma subunit family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	urea catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	nickel cation binding Inferred from electronic annotation. Source: InterPro urease activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 100	100	Urease subunit gamma 2 HAMAP-Rule MF_00739		PRO_0000098000

Sequences

	Sequence		Length	Mass (Da)
	Q57CF0 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: FABF969BACC53D05	FASTA	100	10,943
	10 20 30 40 50 60 MHLTPREFDK LVIHMLSDVA LKRKNKGLKL NHPEAVAVLS AYVLDGAREG KTVEEVMDGA 70 80 90 100 RSVLKADDVM DGVPDLLPLI QVEAVFSDGS RLVSLHNPIT

References

[1]

"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017223 Genomic DNA. Translation: AAX74684.1.
RefSeq	YP_222045.1. NC_006932.1.
3D structure databases
ProteinModelPortal	Q57CF0.
SMR	Q57CF0. Positions 1-100.
ModBase	Search...
Protein-protein interaction databases
STRING	262698.BruAb1_1353.
Proteomic databases
PRIDE	Q57CF0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAX74684; AAX74684; BruAb1_1353.
GeneID	3340379.
KEGG	bmb:BruAb1_1353.
PATRIC	17824433. VBIBruAbo15061_1432.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0831.
HOGENOM	HOG000075053.
KO	K01430.
OMA	KLMVYTL.
ProtClustDB	PRK13242.
Enzyme and pathway databases
BioCyc	BABO262698:GJC2-1382-MONOMER.
UniPathway	UPA00258; UER00370.
Family and domain databases
Gene3D	3.30.280.10. 1 hit.
HAMAP	MF_00739. Urease_gamma.
InterPro	IPR002026. Urease_gamma/gamma-beta_su. IPR012010. Urease_gamma_su. [Graphical view]
Pfam	PF00547. Urease_gamma. 1 hit. [Graphical view]
PIRSF	PIRSF001223. Urease_gamma. 1 hit.
ProDom	PD002319. Urease_gamma_reg. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF54111. Urease_gamma_reg. 1 hit.
TIGRFAMs	TIGR00193. urease_gam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

URE32_BRUAB

Accession

Primary (citable) accession number: Q57CF0

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 21, 2005
Last sequence update:	May 10, 2005
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program