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Q57CF0 (URE32_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Urease subunit gamma 2

EC=3.5.1.5
Alternative name(s):
Urea amidohydrolase subunit gamma 2
Gene names
Name:ureA2
Synonyms:ureA, ureA-2
Ordered Locus Names:BruAb1_1353
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length100 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Urea + H2O = CO2 + 2 NH3. HAMAP-Rule MF_00739

Pathway

Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. HAMAP-Rule MF_00739

Subunit structure

Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00739.

Sequence similarities

Belongs to the urease gamma subunit family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processurea catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionnickel cation binding

Inferred from electronic annotation. Source: InterPro

urease activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 100100Urease subunit gamma 2 HAMAP-Rule MF_00739
PRO_0000098000

Sequences

Sequence LengthMass (Da)Tools
Q57CF0 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: FABF969BACC53D05

FASTA10010,943
        10         20         30         40         50         60 
MHLTPREFDK LVIHMLSDVA LKRKNKGLKL NHPEAVAVLS AYVLDGAREG KTVEEVMDGA 

        70         80         90        100 
RSVLKADDVM DGVPDLLPLI QVEAVFSDGS RLVSLHNPIT 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017223 Genomic DNA. Translation: AAX74684.1.
RefSeqYP_222045.1. NC_006932.1.

3D structure databases

ProteinModelPortalQ57CF0.
SMRQ57CF0. Positions 1-100.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262698.BruAb1_1353.

Proteomic databases

PRIDEQ57CF0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX74684; AAX74684; BruAb1_1353.
GeneID3340379.
KEGGbmb:BruAb1_1353.
PATRIC17824433. VBIBruAbo15061_1432.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0831.
HOGENOMHOG000075053.
KOK01430.
OMAMADASHA.
OrthoDBEOG69PQ9G.

Enzyme and pathway databases

BioCycBABO262698:GJC2-1382-MONOMER.
UniPathwayUPA00258; UER00370.

Family and domain databases

Gene3D3.30.280.10. 1 hit.
HAMAPMF_00739. Urease_gamma.
InterProIPR002026. Urease_gamma/gamma-beta_su.
IPR012010. Urease_gamma_su.
[Graphical view]
PfamPF00547. Urease_gamma. 1 hit.
[Graphical view]
PIRSFPIRSF001223. Urease_gamma. 1 hit.
ProDomPD002319. Urease_gamma_reg. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF54111. SSF54111. 1 hit.
TIGRFAMsTIGR00193. urease_gam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameURE32_BRUAB
AccessionPrimary (citable) accession number: Q57CF0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: May 10, 2005
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names