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Q57CE6

- UREF2_BRUAB

UniProt

Q57CE6 - UREF2_BRUAB

Protein

Urease accessory protein UreF 2

Gene

ureF2

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
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    Functioni

    Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.UniRule annotation

    GO - Molecular functioni

    1. nickel cation binding Source: InterPro

    GO - Biological processi

    1. nitrogen compound metabolic process Source: InterPro

    Keywords - Molecular functioni

    Chaperone

    Keywords - Biological processi

    Nickel insertion

    Enzyme and pathway databases

    BioCyciBABO262698:GJC2-1386-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Urease accessory protein UreF 2UniRule annotation
    Gene namesi
    Name:ureF2UniRule annotation
    Ordered Locus Names:BruAb1_1357
    OrganismiBrucella abortus biovar 1 (strain 9-941)
    Taxonomic identifieri262698 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000540: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 243243Urease accessory protein UreF 2PRO_0000344084Add
    BLAST

    Interactioni

    Subunit structurei

    UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.UniRule annotation

    Protein-protein interaction databases

    STRINGi262698.BruAb1_1357.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UreF family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0830.
    HOGENOMiHOG000049665.
    KOiK03188.
    OMAiCHERADR.
    OrthoDBiEOG64N9W2.

    Family and domain databases

    HAMAPiMF_01385. UreF.
    InterProiIPR002639. UreF.
    [Graphical view]
    PfamiPF01730. UreF. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009467. Ureas_acces_UreF. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q57CE6-1 [UniParc]FASTAAdd to Basket

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    MTMRTATITE FSSSYRSLPG LLHLLQFGDS ALPIGGFSFS NGLESAIQQN    50
    LVHDKETLRE FTLTAMNQAA TSDGIALLTA HRAARADDRG ALQVIDKAVF 100
    ERKLNEETRL MTVRMGRKLC ELSASIIDDR LNRDWLECIK TAETPGTHPV 150
    SLGLAFAALD VDGRDAFGAQ QYGVATTILG AALRLMRVSF MDTQKILLEA 200
    TSTVAPAYEE IADAGIEDMA SFAPMVDILA AVHVKGHVRM FMN 243
    Length:243
    Mass (Da):26,465
    Last modified:May 10, 2005 - v1
    Checksum:iCE0A0602F0527ECB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX74688.1.
    RefSeqiYP_222049.1. NC_006932.1.

    Genome annotation databases

    EnsemblBacteriaiAAX74688; AAX74688; BruAb1_1357.
    GeneIDi3340383.
    KEGGibmb:BruAb1_1357.
    PATRICi17824441. VBIBruAbo15061_1436.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX74688.1 .
    RefSeqi YP_222049.1. NC_006932.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262698.BruAb1_1357.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAX74688 ; AAX74688 ; BruAb1_1357 .
    GeneIDi 3340383.
    KEGGi bmb:BruAb1_1357.
    PATRICi 17824441. VBIBruAbo15061_1436.

    Phylogenomic databases

    eggNOGi COG0830.
    HOGENOMi HOG000049665.
    KOi K03188.
    OMAi CHERADR.
    OrthoDBi EOG64N9W2.

    Enzyme and pathway databases

    BioCyci BABO262698:GJC2-1386-MONOMER.

    Family and domain databases

    HAMAPi MF_01385. UreF.
    InterProi IPR002639. UreF.
    [Graphical view ]
    Pfami PF01730. UreF. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009467. Ureas_acces_UreF. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
      Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
      J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 9-941.

    Entry informationi

    Entry nameiUREF2_BRUAB
    AccessioniPrimary (citable) accession number: Q57CE6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 22, 2008
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella abortus strain 9-941
      Brucella abortus (strain 9-941): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3