Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q57BH8

- RUVB_BRUAB

UniProt

Q57BH8 - RUVB_BRUAB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Holliday junction ATP-dependent DNA helicase RuvB

Gene

ruvB

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi59 – 668ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. DNA binding Source: InterPro
  3. four-way junction helicase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA recombination Source: UniProtKB-HAMAP
  2. DNA repair Source: UniProtKB-HAMAP
  3. SOS response Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase

Keywords - Biological processi

DNA damage, DNA recombination, DNA repair, SOS response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO262698:GJC2-1727-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Holliday junction ATP-dependent DNA helicase RuvBUniRule annotation (EC:3.6.4.12UniRule annotation)
Gene namesi
Name:ruvBUniRule annotation
Ordered Locus Names:BruAb1_1687
OrganismiBrucella abortus biovar 1 (strain 9-941)
Taxonomic identifieri262698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000540: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 346346Holliday junction ATP-dependent DNA helicase RuvBPRO_0000235351Add
BLAST

Interactioni

Subunit structurei

Forms a complex with RuvA.UniRule annotation

Protein-protein interaction databases

STRINGi262698.BruAb1_1687.

Structurei

3D structure databases

ProteinModelPortaliQ57BH8.
SMRiQ57BH8. Positions 19-330.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RuvB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2255.
HOGENOMiHOG000218623.
KOiK03551.
OMAiLEFYTIE.
OrthoDBiEOG6SR93S.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00016. DNA_helic_RuvB.
InterProiIPR003593. AAA+_ATPase.
IPR000641. CbxX_CfqX.
IPR004605. DNA_helicase_Holl-junc_RuvB.
IPR008823. DNA_helicase_Holl-junc_RuvB_C.
IPR008824. DNA_helicase_Holl-junc_RuvB_N.
IPR027417. P-loop_NTPase.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF05491. RuvB_C. 1 hit.
PF05496. RuvB_N. 1 hit.
[Graphical view]
PRINTSiPR00819. CBXCFQXSUPER.
ProDomiPD005323. DNA_helicase_Holl-junc_RuvB_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00635. ruvB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q57BH8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDRNPLIDA DRRADEDNTL RPQTLDDFVG QAAARANLKV FIEAAKVRGE
60 70 80 90 100
ALDHVLFVGP PGLGKTTLAQ IMAKELGVNF RSTSGPVIAK AGDLAALLTN
110 120 130 140 150
LEERDVLFID EIHRLSPAVE EILYPAMEDF QLDLIIGEGP AARSVKIDLA
160 170 180 190 200
KFTLVAATTR LGLLTTPLRD RFGIPVRLNF YTVEELEYIV RRGARIMQMG
210 220 230 240 250
ISSDGAREVA RRSRGTPRIA GRLLRRVRDF ALVAGADIID RRIADEALSR
260 270 280 290 300
LEVDNRGLDQ LDRRYLNIIA RNFGGGPVGI ETIAAGLSEP RDAIEDIIEP
310 320 330 340
YLIQQGFLQR TPRGRVLTAV AWQHLGLPAP AEIIQQSQYG LFMEDE
Length:346
Mass (Da):38,241
Last modified:May 10, 2005 - v1
Checksum:iE6671068908197AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017223 Genomic DNA. Translation: AAX75006.1.
RefSeqiYP_222367.1. NC_006932.1.

Genome annotation databases

EnsemblBacteriaiAAX75006; AAX75006; BruAb1_1687.
GeneIDi3339647.
KEGGibmb:BruAb1_1687.
PATRICi17825158. VBIBruAbo15061_1781.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017223 Genomic DNA. Translation: AAX75006.1 .
RefSeqi YP_222367.1. NC_006932.1.

3D structure databases

ProteinModelPortali Q57BH8.
SMRi Q57BH8. Positions 19-330.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 262698.BruAb1_1687.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX75006 ; AAX75006 ; BruAb1_1687 .
GeneIDi 3339647.
KEGGi bmb:BruAb1_1687.
PATRICi 17825158. VBIBruAbo15061_1781.

Phylogenomic databases

eggNOGi COG2255.
HOGENOMi HOG000218623.
KOi K03551.
OMAi LEFYTIE.
OrthoDBi EOG6SR93S.

Enzyme and pathway databases

BioCyci BABO262698:GJC2-1727-MONOMER.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00016. DNA_helic_RuvB.
InterProi IPR003593. AAA+_ATPase.
IPR000641. CbxX_CfqX.
IPR004605. DNA_helicase_Holl-junc_RuvB.
IPR008823. DNA_helicase_Holl-junc_RuvB_C.
IPR008824. DNA_helicase_Holl-junc_RuvB_N.
IPR027417. P-loop_NTPase.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF05491. RuvB_C. 1 hit.
PF05496. RuvB_N. 1 hit.
[Graphical view ]
PRINTSi PR00819. CBXCFQXSUPER.
ProDomi PD005323. DNA_helicase_Holl-junc_RuvB_C. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00382. AAA. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00635. ruvB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
    Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
    J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 9-941.

Entry informationi

Entry nameiRUVB_BRUAB
AccessioniPrimary (citable) accession number: Q57BH8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: May 10, 2005
Last modified: October 1, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 9-941
    Brucella abortus (strain 9-941): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3