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Q57B45

- OBG_BRUAB

UniProt

Q57B45 - OBG_BRUAB

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Protein
GTPase Obg
Gene
obg, BruAb1_1824
Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate By similarity. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control Reviewed prediction.UniRule annotation

Cofactori

Magnesium Reviewed prediction.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi166 – 1738GTP By similarity
Nucleotide bindingi212 – 2165GTP By similarity
Nucleotide bindingi279 – 2824GTP By similarity

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBABO262698:GJC2-1864-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTPase Obg
    Alternative name(s):
    GTP-binding protein Obg
    Gene namesi
    Name:obg
    Ordered Locus Names:BruAb1_1824
    OrganismiBrucella abortus biovar 1 (strain 9-941)
    Taxonomic identifieri262698 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000540: Chromosome I

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 341341GTPase ObgUniRule annotation
    PRO_0000385765Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Protein-protein interaction databases

    STRINGi262698.BruAb1_1824.

    Structurei

    3D structure databases

    ProteinModelPortaliQ57B45.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini160 – 327168OBG-type G
    Add
    BLAST

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0536.
    HOGENOMiHOG000019084.
    KOiK03979.
    OMAiVINAPAT.
    OrthoDBiEOG6H1Q1M.

    Family and domain databases

    Gene3Di2.70.210.12. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_01454. GTPase_Obg.
    InterProiIPR014100. GTP-bd_Obg/CgtA.
    IPR006074. GTP1-OBG_CS.
    IPR006169. GTP1_OBG_dom.
    IPR006073. GTP_binding_domain.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PANTHERiPTHR11702:SF3. PTHR11702:SF3. 1 hit.
    PfamiPF01018. GTP1_OBG. 1 hit.
    PF01926. MMR_HSR1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
    PRINTSiPR00326. GTP1OBG.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    SSF82051. SSF82051. 1 hit.
    TIGRFAMsiTIGR02729. Obg_CgtA. 1 hit.
    PROSITEiPS51710. G_OBG. 1 hit.
    PS00905. GTP1_OBG. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q57B45-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKFLDQAKIY IRSGNGGAGA VSFRREKFLE FGGPDGGDGG RGGDVWVEAV    50
    DGLNTLIDYR YQQHFKAKTG MHGMGRNMTG GKGDDVVLRV PVGTQIFEED 100
    NETLICDITE VGQRYRLAKG GNGGFGNLHF TTSTNRAPRR ANPGQEGIER 150
    TIWLRLKLIA DAGLVGLPNA GKSTFLASVT AAKPKIADYP FTTLHPNLGV 200
    ARIDGREFVI ADIPGLIEGA SEGVGLGDRF LGHVERTRVL LHLVSAQEED 250
    VAKAYQVIRG ELEAYEHGLA DKPEIVALSQ VDTLDPETRK AKVKALKKAC 300
    GCEPLLLSAV SHEGLNDTLR QLARIIDLSR AEEAGTAQAE E 341
    Length:341
    Mass (Da):36,789
    Last modified:May 10, 2005 - v1
    Checksum:i7C440746D70AB29B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX75139.1.
    RefSeqiYP_222500.1. NC_006932.1.

    Genome annotation databases

    EnsemblBacteriaiAAX75139; AAX75139; BruAb1_1824.
    GeneIDi3340402.
    KEGGibmb:BruAb1_1824.
    PATRICi17825453. VBIBruAbo15061_1928.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX75139.1 .
    RefSeqi YP_222500.1. NC_006932.1.

    3D structure databases

    ProteinModelPortali Q57B45.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 262698.BruAb1_1824.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAX75139 ; AAX75139 ; BruAb1_1824 .
    GeneIDi 3340402.
    KEGGi bmb:BruAb1_1824.
    PATRICi 17825453. VBIBruAbo15061_1928.

    Phylogenomic databases

    eggNOGi COG0536.
    HOGENOMi HOG000019084.
    KOi K03979.
    OMAi VINAPAT.
    OrthoDBi EOG6H1Q1M.

    Enzyme and pathway databases

    BioCyci BABO262698:GJC2-1864-MONOMER.

    Family and domain databases

    Gene3Di 2.70.210.12. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_01454. GTPase_Obg.
    InterProi IPR014100. GTP-bd_Obg/CgtA.
    IPR006074. GTP1-OBG_CS.
    IPR006169. GTP1_OBG_dom.
    IPR006073. GTP_binding_domain.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    PANTHERi PTHR11702:SF3. PTHR11702:SF3. 1 hit.
    Pfami PF01018. GTP1_OBG. 1 hit.
    PF01926. MMR_HSR1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
    PRINTSi PR00326. GTP1OBG.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    SSF82051. SSF82051. 1 hit.
    TIGRFAMsi TIGR02729. Obg_CgtA. 1 hit.
    PROSITEi PS51710. G_OBG. 1 hit.
    PS00905. GTP1_OBG. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
      Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
      J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 9-941.

    Entry informationi

    Entry nameiOBG_BRUAB
    AccessioniPrimary (citable) accession number: Q57B45
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 13, 2009
    Last sequence update: May 10, 2005
    Last modified: May 14, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella abortus strain 9-941
      Brucella abortus (strain 9-941): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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