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Q57B45

- OBG_BRUAB

UniProt

Q57B45 - OBG_BRUAB

Protein

GTPase Obg

Gene

obg

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
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    Functioni

    An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi166 – 1738GTPUniRule annotation
    Nucleotide bindingi212 – 2165GTPUniRule annotation
    Nucleotide bindingi279 – 2824GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: UniProtKB-HAMAP
    2. GTP binding Source: UniProtKB-HAMAP
    3. magnesium ion binding Source: InterPro

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBABO262698:GJC2-1864-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTPase ObgUniRule annotation
    Alternative name(s):
    GTP-binding protein ObgUniRule annotation
    Gene namesi
    Name:obgUniRule annotation
    Ordered Locus Names:BruAb1_1824
    OrganismiBrucella abortus biovar 1 (strain 9-941)
    Taxonomic identifieri262698 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000540: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 341341GTPase ObgPRO_0000385765Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi262698.BruAb1_1824.

    Structurei

    3D structure databases

    ProteinModelPortaliQ57B45.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini160 – 327168OBG-type GAdd
    BLAST

    Sequence similaritiesi

    Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0536.
    HOGENOMiHOG000019084.
    KOiK03979.
    OMAiVINAPAT.
    OrthoDBiEOG6H1Q1M.

    Family and domain databases

    Gene3Di2.70.210.12. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_01454. GTPase_Obg.
    InterProiIPR014100. GTP-bd_Obg/CgtA.
    IPR006074. GTP1-OBG_CS.
    IPR006169. GTP1_OBG_dom.
    IPR006073. GTP_binding_domain.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PANTHERiPTHR11702:SF3. PTHR11702:SF3. 1 hit.
    PfamiPF01018. GTP1_OBG. 1 hit.
    PF01926. MMR_HSR1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
    PRINTSiPR00326. GTP1OBG.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    SSF82051. SSF82051. 1 hit.
    TIGRFAMsiTIGR02729. Obg_CgtA. 1 hit.
    PROSITEiPS51710. G_OBG. 1 hit.
    PS00905. GTP1_OBG. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q57B45-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKFLDQAKIY IRSGNGGAGA VSFRREKFLE FGGPDGGDGG RGGDVWVEAV    50
    DGLNTLIDYR YQQHFKAKTG MHGMGRNMTG GKGDDVVLRV PVGTQIFEED 100
    NETLICDITE VGQRYRLAKG GNGGFGNLHF TTSTNRAPRR ANPGQEGIER 150
    TIWLRLKLIA DAGLVGLPNA GKSTFLASVT AAKPKIADYP FTTLHPNLGV 200
    ARIDGREFVI ADIPGLIEGA SEGVGLGDRF LGHVERTRVL LHLVSAQEED 250
    VAKAYQVIRG ELEAYEHGLA DKPEIVALSQ VDTLDPETRK AKVKALKKAC 300
    GCEPLLLSAV SHEGLNDTLR QLARIIDLSR AEEAGTAQAE E 341
    Length:341
    Mass (Da):36,789
    Last modified:May 10, 2005 - v1
    Checksum:i7C440746D70AB29B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX75139.1.
    RefSeqiYP_222500.1. NC_006932.1.

    Genome annotation databases

    EnsemblBacteriaiAAX75139; AAX75139; BruAb1_1824.
    GeneIDi3340402.
    KEGGibmb:BruAb1_1824.
    PATRICi17825453. VBIBruAbo15061_1928.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017223 Genomic DNA. Translation: AAX75139.1 .
    RefSeqi YP_222500.1. NC_006932.1.

    3D structure databases

    ProteinModelPortali Q57B45.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262698.BruAb1_1824.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAX75139 ; AAX75139 ; BruAb1_1824 .
    GeneIDi 3340402.
    KEGGi bmb:BruAb1_1824.
    PATRICi 17825453. VBIBruAbo15061_1928.

    Phylogenomic databases

    eggNOGi COG0536.
    HOGENOMi HOG000019084.
    KOi K03979.
    OMAi VINAPAT.
    OrthoDBi EOG6H1Q1M.

    Enzyme and pathway databases

    BioCyci BABO262698:GJC2-1864-MONOMER.

    Family and domain databases

    Gene3Di 2.70.210.12. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_01454. GTPase_Obg.
    InterProi IPR014100. GTP-bd_Obg/CgtA.
    IPR006074. GTP1-OBG_CS.
    IPR006169. GTP1_OBG_dom.
    IPR006073. GTP_binding_domain.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    PANTHERi PTHR11702:SF3. PTHR11702:SF3. 1 hit.
    Pfami PF01018. GTP1_OBG. 1 hit.
    PF01926. MMR_HSR1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
    PRINTSi PR00326. GTP1OBG.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    SSF82051. SSF82051. 1 hit.
    TIGRFAMsi TIGR02729. Obg_CgtA. 1 hit.
    PROSITEi PS51710. G_OBG. 1 hit.
    PS00905. GTP1_OBG. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
      Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
      J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 9-941.

    Entry informationi

    Entry nameiOBG_BRUAB
    AccessioniPrimary (citable) accession number: Q57B45
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 13, 2009
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella abortus strain 9-941
      Brucella abortus (strain 9-941): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3