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Protein

GTPase Obg

Gene

obg

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi173MagnesiumUniRule annotation1
Metal bindingi193MagnesiumUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi166 – 173GTPUniRule annotation8
Nucleotide bindingi191 – 195GTPUniRule annotation5
Nucleotide bindingi212 – 215GTPUniRule annotation4
Nucleotide bindingi279 – 282GTPUniRule annotation4
Nucleotide bindingi308 – 310GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

GTP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
GTPase ObgUniRule annotation (EC:3.6.5.-UniRule annotation)
Alternative name(s):
GTP-binding protein ObgUniRule annotation
Gene namesi
Name:obgUniRule annotation
Ordered Locus Names:BruAb1_1824
OrganismiBrucella abortus biovar 1 (strain 9-941)
Taxonomic identifieri262698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000540 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003857651 – 341GTPase ObgAdd BLAST341

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ57B45.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini160 – 327OBG-type GUniRule annotationAdd BLAST168

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.UniRule annotation
Contains 1 OBG-type G (guanine nucleotide-binding) domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000019084.
KOiK03979.
OMAiDILWTEL.

Family and domain databases

Gene3Di2.70.210.12. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01454. GTPase_Obg. 1 hit.
InterProiIPR031167. G_OBG.
IPR014100. GTP-bd_Obg/CgtA.
IPR006074. GTP1-OBG_CS.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11702:SF3. PTHR11702:SF3. 1 hit.
PfamiPF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFiPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
TIGRFAMsiTIGR02729. Obg_CgtA. 1 hit.
PROSITEiPS51710. G_OBG. 1 hit.
PS00905. GTP1_OBG. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q57B45-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFLDQAKIY IRSGNGGAGA VSFRREKFLE FGGPDGGDGG RGGDVWVEAV
60 70 80 90 100
DGLNTLIDYR YQQHFKAKTG MHGMGRNMTG GKGDDVVLRV PVGTQIFEED
110 120 130 140 150
NETLICDITE VGQRYRLAKG GNGGFGNLHF TTSTNRAPRR ANPGQEGIER
160 170 180 190 200
TIWLRLKLIA DAGLVGLPNA GKSTFLASVT AAKPKIADYP FTTLHPNLGV
210 220 230 240 250
ARIDGREFVI ADIPGLIEGA SEGVGLGDRF LGHVERTRVL LHLVSAQEED
260 270 280 290 300
VAKAYQVIRG ELEAYEHGLA DKPEIVALSQ VDTLDPETRK AKVKALKKAC
310 320 330 340
GCEPLLLSAV SHEGLNDTLR QLARIIDLSR AEEAGTAQAE E
Length:341
Mass (Da):36,789
Last modified:May 10, 2005 - v1
Checksum:i7C440746D70AB29B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017223 Genomic DNA. Translation: AAX75139.1.
RefSeqiWP_002964923.1. NC_006932.1.

Genome annotation databases

EnsemblBacteriaiAAX75139; AAX75139; BruAb1_1824.
GeneIDi3788344.
KEGGibmb:BruAb1_1824.
PATRICi17825453. VBIBruAbo15061_1928.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017223 Genomic DNA. Translation: AAX75139.1.
RefSeqiWP_002964923.1. NC_006932.1.

3D structure databases

ProteinModelPortaliQ57B45.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAX75139; AAX75139; BruAb1_1824.
GeneIDi3788344.
KEGGibmb:BruAb1_1824.
PATRICi17825453. VBIBruAbo15061_1928.

Phylogenomic databases

HOGENOMiHOG000019084.
KOiK03979.
OMAiDILWTEL.

Family and domain databases

Gene3Di2.70.210.12. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01454. GTPase_Obg. 1 hit.
InterProiIPR031167. G_OBG.
IPR014100. GTP-bd_Obg/CgtA.
IPR006074. GTP1-OBG_CS.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11702:SF3. PTHR11702:SF3. 1 hit.
PfamiPF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFiPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
TIGRFAMsiTIGR02729. Obg_CgtA. 1 hit.
PROSITEiPS51710. G_OBG. 1 hit.
PS00905. GTP1_OBG. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOBG_BRUAB
AccessioniPrimary (citable) accession number: Q57B45
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 13, 2009
Last sequence update: May 10, 2005
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 9-941
    Brucella abortus (strain 9-941): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.