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Q57B45 (OBG_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
GTPase Obg
Alternative name(s):
GTP-binding protein Obg
Gene names
Name:obg
Ordered Locus Names:BruAb1_1824
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate By similarity. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control Potential. HAMAP-Rule MF_01454

Cofactor

Magnesium Potential.

Subunit structure

Monomer By similarity. HAMAP-Rule MF_01454

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01454.

Sequence similarities

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

Contains 1 OBG-type G (guanine nucleotide-binding) domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

GTPase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 341341GTPase Obg HAMAP-Rule MF_01454
PRO_0000385765

Regions

Domain160 – 327168OBG-type G
Nucleotide binding166 – 1738GTP By similarity
Nucleotide binding212 – 2165GTP By similarity
Nucleotide binding279 – 2824GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q57B45 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 7C440746D70AB29B

FASTA34136,789
        10         20         30         40         50         60 
MKFLDQAKIY IRSGNGGAGA VSFRREKFLE FGGPDGGDGG RGGDVWVEAV DGLNTLIDYR 

        70         80         90        100        110        120 
YQQHFKAKTG MHGMGRNMTG GKGDDVVLRV PVGTQIFEED NETLICDITE VGQRYRLAKG 

       130        140        150        160        170        180 
GNGGFGNLHF TTSTNRAPRR ANPGQEGIER TIWLRLKLIA DAGLVGLPNA GKSTFLASVT 

       190        200        210        220        230        240 
AAKPKIADYP FTTLHPNLGV ARIDGREFVI ADIPGLIEGA SEGVGLGDRF LGHVERTRVL 

       250        260        270        280        290        300 
LHLVSAQEED VAKAYQVIRG ELEAYEHGLA DKPEIVALSQ VDTLDPETRK AKVKALKKAC 

       310        320        330        340 
GCEPLLLSAV SHEGLNDTLR QLARIIDLSR AEEAGTAQAE E 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017223 Genomic DNA. Translation: AAX75139.1.
RefSeqYP_222500.1. NC_006932.1.

3D structure databases

ProteinModelPortalQ57B45.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262698.BruAb1_1824.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX75139; AAX75139; BruAb1_1824.
GeneID3340402.
KEGGbmb:BruAb1_1824.
PATRIC17825453. VBIBruAbo15061_1928.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0536.
HOGENOMHOG000019084.
KOK03979.
OMAVINAPAT.
OrthoDBEOG6H1Q1M.

Enzyme and pathway databases

BioCycBABO262698:GJC2-1864-MONOMER.

Family and domain databases

Gene3D2.70.210.12. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_01454. GTPase_Obg.
InterProIPR014100. GTP-bd_Obg/CgtA.
IPR006074. GTP1-OBG_CS.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR11702:SF3. PTHR11702:SF3. 1 hit.
PfamPF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSPR00326. GTP1OBG.
SUPFAMSSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
TIGRFAMsTIGR02729. Obg_CgtA. 1 hit.
PROSITEPS51710. G_OBG. 1 hit.
PS00905. GTP1_OBG. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameOBG_BRUAB
AccessionPrimary (citable) accession number: Q57B45
Entry history
Integrated into UniProtKB/Swiss-Prot: October 13, 2009
Last sequence update: May 10, 2005
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names