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Q57AJ8 (RSMG_BRUAB) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase G

EC=2.1.1.170
Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase
Gene names
Name:rsmG
Ordered Locus Names:BruAb1_2035
OrganismBrucella abortus biovar 1 (strain 9-941) [Complete proteome] [HAMAP]
Taxonomic identifier262698 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the N7 position of guanine in position 527 of 16S rRNA By similarity. HAMAP-Rule MF_00074

Catalytic activity

S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA. HAMAP-Rule MF_00074

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00074.

Sequence similarities

Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionrRNA (guanine-N7-)-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 213213Ribosomal RNA small subunit methyltransferase G HAMAP-Rule MF_00074
PRO_0000184228

Regions

Region128 – 1292S-adenosyl-L-methionine binding By similarity

Sites

Binding site751S-adenosyl-L-methionine; via carbonyl oxygen By similarity
Binding site801S-adenosyl-L-methionine; via carbonyl oxygen By similarity
Binding site1441S-adenosyl-L-methionine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q57AJ8 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: D9B5B1C9467AB2E2

FASTA21323,473
        10         20         30         40         50         60 
MSADIRFDSL KTIVPAVSRE TADRLIAFED LFRKWSKAIN LASPSTLADL WNRHILDSAQ 

        70         80         90        100        110        120 
LFPLAKEATR WLDIGSGGGF PGIVTACFLA ERSGGCIDLV ESAGKKAAFL RTAAGHLHVP 

       130        140        150        160        170        180 
ARVHSARIES MWEKIETPQV VTARALASLG DLFTLAEPWL SDGAKALFQK GRDYQREIDE 

       190        200        210 
SRVGWSFDLV KHPSAIDQAS VILEISNLRR KTD 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017223 Genomic DNA. Translation: AAX75336.1.
RefSeqYP_222697.1. NC_006932.1.

3D structure databases

ProteinModelPortalQ57AJ8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262698.BruAb1_2035.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAX75336; AAX75336; BruAb1_2035.
GeneID3339666.
KEGGbmb:BruAb1_2035.
PATRIC17825917. VBIBruAbo15061_2146.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0357.
HOGENOMHOG000221015.
KOK03501.
OMAQWQAKTN.
OrthoDBEOG6HF639.

Enzyme and pathway databases

BioCycBABO262698:GJC2-2085-MONOMER.

Family and domain databases

Gene3D3.40.50.150. 1 hit.
HAMAPMF_00074. 16SrRNA_methyltr_G.
InterProIPR003682. rRNA_ssu_MeTfrase_G.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PfamPF02527. GidB. 1 hit.
[Graphical view]
PIRSFPIRSF003078. GidB. 1 hit.
SUPFAMSSF53335. SSF53335. 1 hit.
TIGRFAMsTIGR00138. gidB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRSMG_BRUAB
AccessionPrimary (citable) accession number: Q57AJ8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: May 10, 2005
Last modified: June 11, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names