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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaKUniRule annotation
Alternative name(s):
HSP70UniRule annotation
Heat shock 70 kDa proteinUniRule annotation
Heat shock protein 70UniRule annotation
Gene namesi
Name:dnaKUniRule annotation
Ordered Locus Names:BruAb1_2100
OrganismiBrucella abortus biovar 1 (strain 9-941)
Taxonomic identifieri262698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000540 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002259431 – 637Chaperone protein DnaKAdd BLAST637

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei198Phosphothreonine; by autocatalysisUniRule annotation1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ57AD7.

Expressioni

Inductioni

By stress conditions e.g. heat shock.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ57AD7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000228136.
KOiK04043.
OMAiEKMAPPQ.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q57AD7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVIGIDLG TTNSCVAVMD GKNAKVIENA EGARTTPSII AFTDGDERLA
60 70 80 90 100
GQPAKRQAVT NPEGTLFAVK RLIGRRYDDP MVTKDKDLVP YKIVKGDNGD
110 120 130 140 150
AWVEVHGKKY SPSQISAMIL QKMKETAESY LGETVTQAVI TVPAYFNDAQ
160 170 180 190 200
RQATKDAGKI AGLEVLRIIN EPTAAALAYG LDKSEGKTIA VYDLGGGTFD
210 220 230 240 250
VSVLEIGDGV FEVKSTNGDT FLGGEDFDIR LVEYLVAEFK KESGIDLKND
260 270 280 290 300
KLALQRLKEA AEKAKIELSS SQQTEINLPF ITADQTGPKH LAIKLSRAKF
310 320 330 340 350
ESLVDDLVQR TVEPCKAALK DAGLKAGEID EVVLVGGMTR MPKIQEVVKA
360 370 380 390 400
FFGKEPHKGV NPDEVVAMGA AIQGGVLQGD VKDVLLLDVT PLSLGIETLG
410 420 430 440 450
GVFTRLIERN TTIPTKKSQT FSTAEDNQSA VTIRVFQGER EMAADNKLLG
460 470 480 490 500
QFDLVGIPPA PRGVPQIEVT FDIDANGIVN VSAKDKGTGK EHQIRIQASG
510 520 530 540 550
GLSDADIEKM VKDAEANAEA DKKRRESVEA KNQAESLVHS TEKSLAEYGD
560 570 580 590 600
KVSADDKKAI EDAIAALKTS LEGEDAEDIK AKTQALAEVS MKLGQAMYEA
610 620 630
AQAAEGAGAE GGEQASSSKD DVVDADYEEI DDNKKSS
Length:637
Mass (Da):68,194
Last modified:May 10, 2005 - v1
Checksum:iC659ABDE5529B91E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017223 Genomic DNA. Translation: AAX75397.1.
RefSeqiWP_002969217.1. NC_006932.1.

Genome annotation databases

EnsemblBacteriaiAAX75397; AAX75397; BruAb1_2100.
GeneIDi3788553.
KEGGibmb:BruAb1_2100.
PATRICi17826061. VBIBruAbo15061_2218.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017223 Genomic DNA. Translation: AAX75397.1.
RefSeqiWP_002969217.1. NC_006932.1.

3D structure databases

ProteinModelPortaliQ57AD7.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ57AD7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAX75397; AAX75397; BruAb1_2100.
GeneIDi3788553.
KEGGibmb:BruAb1_2100.
PATRICi17826061. VBIBruAbo15061_2218.

Phylogenomic databases

HOGENOMiHOG000228136.
KOiK04043.
OMAiEKMAPPQ.

Miscellaneous databases

PROiQ57AD7.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNAK_BRUAB
AccessioniPrimary (citable) accession number: Q57AD7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: May 10, 2005
Last modified: November 2, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 9-941
    Brucella abortus (strain 9-941): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.