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Q57A43

- MGTC_BRUAB

UniProt

Q57A43 - MGTC_BRUAB

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Protein
Protein MgtC
Gene
mgtC, BruAb2_0040
Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Virulence factor required for growth in low Mg2+ medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na+/K+-ATPase By similarity.

GO - Biological processi

  1. pathogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Virulence

Enzyme and pathway databases

BioCyciBABO262698:GJC2-2248-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MgtC
Gene namesi
Name:mgtC
Ordered Locus Names:BruAb2_0040
OrganismiBrucella abortus biovar 1 (strain 9-941)
Taxonomic identifieri262698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000540: Chromosome II

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei5 – 2521Helical; Reviewed prediction
Add
BLAST
Transmembranei38 – 5821Helical; Reviewed prediction
Add
BLAST
Transmembranei66 – 8621Helical; Reviewed prediction
Add
BLAST
Transmembranei105 – 12521Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 238238Protein MgtC
PRO_0000250523Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi262698.BruAb2_0040.

Family & Domainsi

Sequence similaritiesi

Belongs to the MgtC/SapB family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1285.
HOGENOMiHOG000080251.
KOiK07507.
OMAiICKSQAE.
OrthoDBiEOG6H4KB4.

Family and domain databases

InterProiIPR003416. MgtCSapBSrpB_transpt.
[Graphical view]
PfamiPF02308. MgtC. 1 hit.
[Graphical view]
PRINTSiPR01837. MGTCSAPBPROT.

Sequencei

Sequence statusi: Complete.

Q57A43-1 [UniParc]FASTAAdd to Basket

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MVWKPLAHTA ACLAGAFLLG GLIGFERQFR HRLAGLRTNT LVAVGAATFV    50
VFSSLVSGDS SPTRVAAQIV SGIGFLGAGI IFKEGFNVRG LNTAATLWCS 100
AAVGVLCGAG LISHAAVATV FIIAVNALLR PLVQVLEFQA MRRGAFQPTY 150
AIDIICHGDA EAQVRALLLR DIGDHLHIHE LESSNIEGTN RVEVSATVRA 200
DQRQDRLLEQ IVGHLSLEPR ITSARWRIED DSGGLSGL 238
Length:238
Mass (Da):25,357
Last modified:May 10, 2005 - v1
Checksum:i2D1E20FA7069CE60
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017224 Genomic DNA. Translation: AAX75491.1.
RefSeqiYP_222852.1. NC_006933.1.

Genome annotation databases

EnsemblBacteriaiAAX75491; AAX75491; BruAb2_0040.
GeneIDi3341895.
KEGGibmb:BruAb2_0040.
PATRICi17826271. VBIBruAbo15061_2322.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017224 Genomic DNA. Translation: AAX75491.1 .
RefSeqi YP_222852.1. NC_006933.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 262698.BruAb2_0040.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX75491 ; AAX75491 ; BruAb2_0040 .
GeneIDi 3341895.
KEGGi bmb:BruAb2_0040.
PATRICi 17826271. VBIBruAbo15061_2322.

Phylogenomic databases

eggNOGi COG1285.
HOGENOMi HOG000080251.
KOi K07507.
OMAi ICKSQAE.
OrthoDBi EOG6H4KB4.

Enzyme and pathway databases

BioCyci BABO262698:GJC2-2248-MONOMER.

Family and domain databases

InterProi IPR003416. MgtCSapBSrpB_transpt.
[Graphical view ]
Pfami PF02308. MgtC. 1 hit.
[Graphical view ]
PRINTSi PR01837. MGTCSAPBPROT.
ProtoNeti Search...

Publicationsi

  1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
    Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
    J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 9-941.

Entry informationi

Entry nameiMGTC_BRUAB
AccessioniPrimary (citable) accession number: Q57A43
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: May 10, 2005
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 9-941
    Brucella abortus (strain 9-941): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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