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Reviewed, UniProtKB/Swiss-Prot Q579E2 (DADA_BRUAB)

Last modified November 4, 2008. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    D-amino acid dehydrogenase small subunit
    EC=1.4.99.1
Gene names
Name: dadA
Ordered Locus Names: BruAb2_0309
OrganismBrucella abortus [Complete proteome] [HAMAP]
Taxonomic identifier235 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Oxidative deamination of D-amino acids By similarity.

Catalytic activity

A D-amino acid + H(2)O + acceptor = a 2-oxo acid + NH(3) + reduced acceptor.

Cofactor

FAD By similarity.

Pathway

Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1.

Subunit structure

Heterodimer of a small and a large subunit By similarity.

Sequence similarities

Belongs to the dadA oxidoreductase family.

Ontologies

Keywords

   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome

Gene Ontology (GO)

   Biological processalanine catabolic process

Inferred from electronic annotation. Source: HAMAP

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionD-amino-acid dehydrogenase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416D-amino acid dehydrogenase small subunit
PRO_1000066070

Regions

Nucleotide binding3 – 1715FAD Potential

Sequences

Sequence LengthMass (Da)Tools
Q579E2-1 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 7480382FF5614CA2

FASTA41645,110
        10         20         30         40         50         60 
MQITILGSGV IGVTTAYYLA KLGHEVTVID REEGPALETS FANAGQVSPG YASPWAAPGI 

        70         80         90        100        110        120 
PLKAAKWLFQ KHAPLILRLT TDPVQYRWLL QMLANCTDSR YKINKTRMVR VAEYSRDCLI 

       130        140        150        160        170        180 
ELRKDTGIEY DQRSQGTLQL FREQYQLDGI GKDIEVLRQD GVPFEVLDRD GCVNVEPALA 

       190        200        210        220        230        240 
HAKDKFVGGL RLPNDETGDC FKFTNALAKI AEGLGVKFRF GVNIKSLLMS GGKISGVETS 

       250        260        270        280        290        300 
EGIVTAERYV VALGSYTPAL IKALGLNAPI YPVKGYSITA PIVDESRAPV STVLDESYKI 

       310        320        330        340        350        360 
AITRLGDRIR VGGMAEVSGF TDDLPAARRA TLDLSVTDLF PGGDLKAATF WSGLRPMTPD 

       370        380        390        400        410 
STPIIGGTRY DNLFINAGHG TLGWTMACGS GRLLADLISG NKADIRADDL GIARYN 

« Hide

References

[1]"Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9-941 / Biovar 1.

Cross-references

Sequence databases

AE017224 Genomic DNA. Translation: AAX75742.1.
RefSeqYP_223103.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3341955.
GenomeReviewsGene locus BruAb2_0309 in contig AE017224_GR.
KEGGbmb:BruAb2_0309.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ579E2.

Enzyme and pathway databases

BioCycBABO262698:BRUAB2_0309-MON.

Family and domain databases

HAMAPMF_01202.
[Tree]
InterProIPR002110. ANK.
IPR006076. FAD-dep_OxRdtase.
[Graphical view]
PfamPF01266. DAO. 1 hit.
[Graphical view]
PRINTSPR01415. ANKYRIN.
ProDomPD000139. FAD_pyr_redox. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameDADA_BRUAB
AccessionPrimary (citable) accession number: Q579E2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 10, 2005
Last modified: November 4, 2008
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Brucella abortus strain 9-941

Brucella abortus (strain 9-941): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents