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Q57983

- MT51_METJA

UniProt

Q57983 - MT51_METJA

Protein

Probable modification methylase MJ0563

Gene

MJ0563

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei77 – 771PROSITE-ProRule annotation

    GO - Molecular functioni

    1. DNA (cytosine-5-)-methyltransferase activity Source: UniProtKB-EC
    2. DNA binding Source: InterPro

    GO - Biological processi

    1. DNA restriction-modification system Source: UniProtKB-KW

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    Restriction system

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Protein family/group databases

    REBASEi3888. M.MjaORF563P.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable modification methylase MJ0563 (EC:2.1.1.37)
    Alternative name(s):
    Cytosine-specific methyltransferase MJ0563
    M.MjaVIIIP
    Gene namesi
    Ordered Locus Names:MJ0563
    OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
    Taxonomic identifieri243232 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
    ProteomesiUP000000805: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 310310Probable modification methylase MJ0563PRO_0000087916Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243232.MJ0563.

    Structurei

    3D structure databases

    ProteinModelPortaliQ57983.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 310310SAM-dependent MTase C5-typePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.PROSITE-ProRule annotation
    Contains 1 SAM-dependent MTase C5-type domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0270.
    KOiK00558.
    OMAiAKNHEIK.
    PhylomeDBiQ57983.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    InterProiIPR001525. C5_MeTfrase.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view]
    PANTHERiPTHR10629. PTHR10629. 1 hit.
    PfamiPF00145. DNA_methylase. 1 hit.
    [Graphical view]
    PRINTSiPR00105. C5METTRFRASE.
    SUPFAMiSSF53335. SSF53335. 1 hit.
    PROSITEiPS51679. SAM_MT_C5. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q57983-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNVIDLFSGC GGFSKGFLDE NFRILGAIEN FKPVVKTYLY NIKAPVWMDD    50
    IKRIPPKAFD EFIKNEKVDV IIGSPPCEPF TKANKLIKDN PLDRLYKDKV 100
    GRLVLYYIDY VNYFTQRNDD LIFVMENVPQ IKEIKDELKK LFGDIGHKVY 150
    FNILRAEDYG NPSKRARMFI SNIKLKPKKV DKLVVVEEAL KDIPKDAKNH 200
    EIKKLSKEKV EMISKLKWGE ALYRYRGKKK LMFNWYKLHP KKLAPTVKGR 250
    SRFIHPYEDR LLTVREQARL MSYPDDFVFF GGRDVQYNQI GESVPPILGR 300
    AIAKEIKKQL 310
    Length:310
    Mass (Da):36,290
    Last modified:November 1, 1996 - v1
    Checksum:i0F983B2193692D78
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98555.1.
    PIRiC64370.
    RefSeqiNP_247542.1. NC_000909.1.

    Genome annotation databases

    EnsemblBacteriaiAAB98555; AAB98555; MJ_0563.
    GeneIDi1451428.
    KEGGimja:MJ_0563.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98555.1 .
    PIRi C64370.
    RefSeqi NP_247542.1. NC_000909.1.

    3D structure databases

    ProteinModelPortali Q57983.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243232.MJ0563.

    Protein family/group databases

    REBASEi 3888. M.MjaORF563P.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB98555 ; AAB98555 ; MJ_0563 .
    GeneIDi 1451428.
    KEGGi mja:MJ_0563.

    Phylogenomic databases

    eggNOGi COG0270.
    KOi K00558.
    OMAi AKNHEIK.
    PhylomeDBi Q57983.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    InterProi IPR001525. C5_MeTfrase.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view ]
    PANTHERi PTHR10629. PTHR10629. 1 hit.
    Pfami PF00145. DNA_methylase. 1 hit.
    [Graphical view ]
    PRINTSi PR00105. C5METTRFRASE.
    SUPFAMi SSF53335. SSF53335. 1 hit.
    PROSITEi PS51679. SAM_MT_C5. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

    Entry informationi

    Entry nameiMT51_METJA
    AccessioniPrimary (citable) accession number: Q57983
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Methanococcus jannaschii
      Methanococcus jannaschii: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3