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Q57983 (MT51_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable modification methylase MJ0563

EC=2.1.1.37
Alternative name(s):
Cytosine-specific methyltransferase MJ0563
M.MjaVIIIP
Gene names
Ordered Locus Names:MJ0563
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.

Sequence similarities

Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

Contains 1 SAM-dependent MTase C5-type domain.

Ontologies

Keywords
   Biological processRestriction system
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA restriction-modification system

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionDNA (cytosine-5-)-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

DNA binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 310310Probable modification methylase MJ0563
PRO_0000087916

Regions

Domain1 – 310310SAM-dependent MTase C5-type

Sites

Active site771 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q57983 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 0F983B2193692D78

FASTA31036,290
        10         20         30         40         50         60 
MNVIDLFSGC GGFSKGFLDE NFRILGAIEN FKPVVKTYLY NIKAPVWMDD IKRIPPKAFD 

        70         80         90        100        110        120 
EFIKNEKVDV IIGSPPCEPF TKANKLIKDN PLDRLYKDKV GRLVLYYIDY VNYFTQRNDD 

       130        140        150        160        170        180 
LIFVMENVPQ IKEIKDELKK LFGDIGHKVY FNILRAEDYG NPSKRARMFI SNIKLKPKKV 

       190        200        210        220        230        240 
DKLVVVEEAL KDIPKDAKNH EIKKLSKEKV EMISKLKWGE ALYRYRGKKK LMFNWYKLHP 

       250        260        270        280        290        300 
KKLAPTVKGR SRFIHPYEDR LLTVREQARL MSYPDDFVFF GGRDVQYNQI GESVPPILGR 

       310 
AIAKEIKKQL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB98555.1.
PIRC64370.
RefSeqNP_247542.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ57983.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ0563.

Protein family/group databases

REBASE3888. M.MjaORF563P.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB98555; AAB98555; MJ_0563.
GeneID1451428.
KEGGmja:MJ_0563.

Phylogenomic databases

eggNOGCOG0270.
KOK00558.
OMARARMFIS.
ProtClustDBCLSK2749894.

Family and domain databases

InterProIPR001525. C5_MeTfrase.
[Graphical view]
PANTHERPTHR10629. PTHR10629. 1 hit.
PfamPF00145. DNA_methylase. 1 hit.
[Graphical view]
PRINTSPR00105. C5METTRFRASE.
PROSITEPS51679. SAM_MT_C5. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMT51_METJA
AccessionPrimary (citable) accession number: Q57983
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names