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Protein

TATA-box-binding protein

Gene

tbp

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
TATA-box-binding protein
Alternative name(s):
Box A-binding protein
Short name:
BAP
TATA sequence-binding protein
Short name:
TBP
TATA-box factor
Gene namesi
Name:tbp
Ordered Locus Names:MJ0507
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001540081 – 183TATA-box-binding proteinAdd BLAST183

Proteomic databases

PRIDEiQ57930.

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ_0507.

Structurei

Secondary structure

1183
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi9 – 18Combined sources10
Helixi25 – 31Combined sources7
Turni39 – 41Combined sources3
Beta strandi45 – 49Combined sources5
Turni50 – 53Combined sources4
Beta strandi54 – 58Combined sources5
Beta strandi62 – 71Combined sources10
Helixi72 – 88Combined sources17
Beta strandi100 – 109Combined sources10
Helixi116 – 122Combined sources7
Beta strandi126 – 128Combined sources3
Turni130 – 132Combined sources3
Beta strandi133 – 140Combined sources8
Turni141 – 144Combined sources4
Beta strandi145 – 149Combined sources5
Beta strandi153 – 159Combined sources7
Helixi163 – 180Combined sources18

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2Z8UX-ray1.90A/B/P/Q4-183[»]
ProteinModelPortaliQ57930.
SMRiQ57930.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ57930.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati10 – 861Add BLAST77
Repeati101 – 1772Add BLAST77

Sequence similaritiesi

Belongs to the TBP family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
InParanoidiQ57930.
KOiK03120.
OMAiTLPNCEY.
PhylomeDBiQ57930.

Family and domain databases

CDDicd04518. TBP_archaea. 1 hit.
Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch. 1 hit.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR033711. TBP_archaea.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q57930-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIMEPEIKI VNVVVSTKIG DNIDLEEVAM ILENAEYEPE QFPGLVCRLS
60 70 80 90 100
VPKVALLIFR SGKVNCTGAK SKEEAEIAIK KIIKELKDAG IDVIENPEIK
110 120 130 140 150
IQNMVATADL GIEPNLDDIA LMVEGTEYEP EQFPGLVYRL DDPKVVVLIF
160 170 180
GSGKVVITGL KSEEDAKRAL KKILDTIKEV QEL
Length:183
Mass (Da):20,233
Last modified:November 1, 1996 - v1
Checksum:i3C648FA0FC404944
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98497.1.
PIRiC64363.

Genome annotation databases

EnsemblBacteriaiAAB98497; AAB98497; MJ_0507.
KEGGimja:MJ_0507.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98497.1.
PIRiC64363.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2Z8UX-ray1.90A/B/P/Q4-183[»]
ProteinModelPortaliQ57930.
SMRiQ57930.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243232.MJ_0507.

Proteomic databases

PRIDEiQ57930.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB98497; AAB98497; MJ_0507.
KEGGimja:MJ_0507.

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
InParanoidiQ57930.
KOiK03120.
OMAiTLPNCEY.
PhylomeDBiQ57930.

Miscellaneous databases

EvolutionaryTraceiQ57930.

Family and domain databases

CDDicd04518. TBP_archaea. 1 hit.
Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch. 1 hit.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR033711. TBP_archaea.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTBP_METJA
AccessioniPrimary (citable) accession number: Q57930
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.