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Protein

Putative fluoride ion transporter CrcB 4

Gene

crcB4

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Important for reducing fluoride concentration in the cell, thus reducing its toxicity.UniRule annotation

GO - Molecular functioni

  1. inorganic anion transmembrane transporter activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciBABO262698:GJC2-2627-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative fluoride ion transporter CrcB 4UniRule annotation
Gene namesi
Name:crcB4UniRule annotation
Ordered Locus Names:BruAb2_0415
OrganismiBrucella abortus biovar 1 (strain 9-941)
Taxonomic identifieri262698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000540: Chromosome II

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei7 – 2721HelicalUniRule annotationAdd
BLAST
Transmembranei37 – 5721HelicalUniRule annotationAdd
BLAST
Transmembranei60 – 8021HelicalUniRule annotationAdd
BLAST
Transmembranei107 – 12721HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 133133Putative fluoride ion transporter CrcB 4PRO_0000110070Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi262698.BruAb2_0415.

Family & Domainsi

Sequence similaritiesi

Belongs to the CrcB (TC 9.B.71) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0239.
HOGENOMiHOG000052573.
KOiK06199.
OMAiAYPWGTT.
OrthoDBiEOG6WHNZ2.

Family and domain databases

HAMAPiMF_00454. CrcB.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q578U0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVEASILVL VGGFIGGVMR FFLSGYVGRR IGETFPWGTF VVNVSGAFVI
60 70 80 90 100
GTAAGLGARL GGIFSTTIFH EFIMVGLLGG YTTVSSFCLQ SVNLMLDGEQ
110 120 130
RQALFNIVAS ALLCVLAVAA GYGGIMWIME WPG
Length:133
Mass (Da):14,010
Last modified:May 10, 2005 - v1
Checksum:iD157200B458C63A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017224 Genomic DNA. Translation: AAX75844.1.
RefSeqiYP_223205.1. NC_006933.1.

Genome annotation databases

EnsemblBacteriaiAAX75844; AAX75844; BruAb2_0415.
GeneIDi3342055.
KEGGibmb:BruAb2_0415.
PATRICi17827073. VBIBruAbo15061_2717.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017224 Genomic DNA. Translation: AAX75844.1.
RefSeqiYP_223205.1. NC_006933.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi262698.BruAb2_0415.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAX75844; AAX75844; BruAb2_0415.
GeneIDi3342055.
KEGGibmb:BruAb2_0415.
PATRICi17827073. VBIBruAbo15061_2717.

Phylogenomic databases

eggNOGiCOG0239.
HOGENOMiHOG000052573.
KOiK06199.
OMAiAYPWGTT.
OrthoDBiEOG6WHNZ2.

Enzyme and pathway databases

BioCyciBABO262698:GJC2-2627-MONOMER.

Family and domain databases

HAMAPiMF_00454. CrcB.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
    Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
    J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 9-941.

Entry informationi

Entry nameiCRCB4_BRUAB
AccessioniPrimary (citable) accession number: Q578U0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: May 10, 2005
Last modified: January 7, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 9-941
    Brucella abortus (strain 9-941): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.