Reviewed,
UniProtKB/Swiss-Prot Q578J2 (AHPD_BRUAB)
Last modified
November 3, 2009.
Version 23.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Alkyl hydroperoxide reductase ahpD EC=1.11.1.15 Alternative name(s): Alkylhydroperoxidase ahpD | ||||
| Gene names |
| ||||
| Organism | Brucella abortus [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 235 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella |
Protein attributes
| Sequence length | 175 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the ahpC active site cysteine residues and for the regeneration of the ahpC enzyme activity By similarity. |
| Catalytic activity | 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. HAMAP MF_01676 |
| Sequence similarities | Belongs to the ahpD family. |
Ontologies
| Keywords | |
|---|---|
| Domain | Redox-active center |
| Molecular function | Antioxidant Oxidoreductase Peroxidase |
| PTM | Disulfide bond |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | alkyl hydroperoxide reductase activity Inferred from electronic annotation. Source: HAMAP peroxiredoxin activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||
Molecule processing | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 175 | 175 | Alkyl hydroperoxide reductase ahpD HAMAP MF_01676 | PRO_0000359476 | |||||||
Sites | |||||||||||
| Active site | 131 | 1 | Proton donor By similarity | ||||||||
| Active site | 134 | 1 | Cysteine sulfenic acid (-SOH) intermediate By similarity | ||||||||
Amino acid modifications | |||||||||||
| Disulfide bond | 131 ↔ 134 | Alternate By similarity | |||||||||
| Disulfide bond | 134 | Interchain (with ahpC); in linked form By similarity | |||||||||
Sequences
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References
| [1] | "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis." Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. J. Bacteriol. 187:2715-2726(2005) [PubMed: 15805518] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 9-941 / Biovar 1. |
Cross-references
Sequence databases | |
|---|---|
| AE017224 Genomic DNA. Translation: AAX75942.1. | |
| RefSeq | YP_223303.1. |
3D structure databases | |
| ModBase | Search... |
Protein family/group databases | |
| PeroxiBase | 4605. BabAhpD. |
Genome annotation databases | |
| GeneID | 3342335. |
| GenomeReviews | Gene locus BruAb2_0523 in contig AE017224_GR. |
| KEGG | bmb:BruAb2_0523. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q578J2. |
| OMA | MAMNNVY. |
Enzyme and pathway databases | |
| BioCyc | BABO262698:BRUAB2_0523-MON. |
Family and domain databases | |
| HAMAP | MF_01676. [Tree] |
| InterPro | IPR004674. AhpD. IPR004675. AhpD_core. IPR003779. CMD. [Graphical view] |
| Pfam | PF02627. CMD. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00777. ahpD. 1 hit. TIGR00778. ahpD_dom. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | AHPD_BRUAB | ||||||||
| Accession | Primary (citable) accession number: Q578J2 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Brucella abortus strain 9-941 Brucella abortus (strain 9-941): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

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