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Q57893

- TRPF_METJA

UniProt

Q57893 - TRPF_METJA

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
    Short name:
    PRAI
    Gene namesi
    Name:trpF
    Ordered Locus Names:MJ0451
    OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
    Taxonomic identifieri243232 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
    ProteomesiUP000000805: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 226226N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154403Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243232.MJ0451.

    Structurei

    3D structure databases

    ProteinModelPortaliQ57893.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.Curated

    Phylogenomic databases

    eggNOGiCOG0135.
    KOiK01817.
    OMAiETHDWER.
    PhylomeDBiQ57893.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q57893-1 [UniParc]FASTAAdd to Basket

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    MGDDLVKVKI CGITNEEDIA YISKKVHAVG VIVDVPVKTP RKISLDKAIE    50
    LKKYVAPFTS LVTVLMPNSI EEVLEIYNAL KPNAIQLHGF ESLDFVKELN 100
    KLKNTGELNA HIIKVIHIPK DEEIDFKTLL NTAKEYEKYV EAILVDTKIE 150
    SIKLEGKTHN WAVSKKLRES LEKPLILAGG LNKDNVLEAI KTVKPYAIDV 200
    SSSLEAYGGK KDLKKVDEFL EVIKKV 226
    Length:226
    Mass (Da):25,306
    Last modified:November 1, 1996 - v1
    Checksum:i7B83DC1F16C5957E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98440.1.
    PIRiC64356.
    RefSeqiNP_247425.1. NC_000909.1.
    WP_010869950.1. NC_000909.1.

    Genome annotation databases

    EnsemblBacteriaiAAB98440; AAB98440; MJ_0451.
    GeneIDi1451312.
    KEGGimja:MJ_0451.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98440.1 .
    PIRi C64356.
    RefSeqi NP_247425.1. NC_000909.1.
    WP_010869950.1. NC_000909.1.

    3D structure databases

    ProteinModelPortali Q57893.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243232.MJ0451.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB98440 ; AAB98440 ; MJ_0451 .
    GeneIDi 1451312.
    KEGGi mja:MJ_0451.

    Phylogenomic databases

    eggNOGi COG0135.
    KOi K01817.
    OMAi ETHDWER.
    PhylomeDBi Q57893.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

    Entry informationi

    Entry nameiTRPF_METJA
    AccessioniPrimary (citable) accession number: Q57893
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Methanococcus jannaschii
      Methanococcus jannaschii: entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3