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Q57893

- TRPF_METJA

UniProt

Q57893 - TRPF_METJA

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Protein
N-(5'-phosphoribosyl)anthranilate isomerase
Gene
trpF, MJ0451
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:MJ0451
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 226226N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation
PRO_0000154403Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ0451.

Structurei

3D structure databases

ProteinModelPortaliQ57893.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
KOiK01817.
OMAiETHDWER.
PhylomeDBiQ57893.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q57893-1 [UniParc]FASTAAdd to Basket

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MGDDLVKVKI CGITNEEDIA YISKKVHAVG VIVDVPVKTP RKISLDKAIE    50
LKKYVAPFTS LVTVLMPNSI EEVLEIYNAL KPNAIQLHGF ESLDFVKELN 100
KLKNTGELNA HIIKVIHIPK DEEIDFKTLL NTAKEYEKYV EAILVDTKIE 150
SIKLEGKTHN WAVSKKLRES LEKPLILAGG LNKDNVLEAI KTVKPYAIDV 200
SSSLEAYGGK KDLKKVDEFL EVIKKV 226
Length:226
Mass (Da):25,306
Last modified:November 1, 1996 - v1
Checksum:i7B83DC1F16C5957E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB98440.1.
PIRiC64356.
RefSeqiNP_247425.1. NC_000909.1.
WP_010869950.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98440; AAB98440; MJ_0451.
GeneIDi1451312.
KEGGimja:MJ_0451.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB98440.1 .
PIRi C64356.
RefSeqi NP_247425.1. NC_000909.1.
WP_010869950.1. NC_000909.1.

3D structure databases

ProteinModelPortali Q57893.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243232.MJ0451.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB98440 ; AAB98440 ; MJ_0451 .
GeneIDi 1451312.
KEGGi mja:MJ_0451.

Phylogenomic databases

eggNOGi COG0135.
KOi K01817.
OMAi ETHDWER.
PhylomeDBi Q57893.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Entry informationi

Entry nameiTRPF_METJA
AccessioniPrimary (citable) accession number: Q57893
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: September 3, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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