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Q57893

- TRPF_METJA

UniProt

Q57893 - TRPF_METJA

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:MJ0451
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 226226N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154403Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ0451.

Structurei

3D structure databases

ProteinModelPortaliQ57893.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.Curated

Phylogenomic databases

eggNOGiCOG0135.
InParanoidiQ57893.
KOiK01817.
OMAiETHDWER.
PhylomeDBiQ57893.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q57893-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGDDLVKVKI CGITNEEDIA YISKKVHAVG VIVDVPVKTP RKISLDKAIE
60 70 80 90 100
LKKYVAPFTS LVTVLMPNSI EEVLEIYNAL KPNAIQLHGF ESLDFVKELN
110 120 130 140 150
KLKNTGELNA HIIKVIHIPK DEEIDFKTLL NTAKEYEKYV EAILVDTKIE
160 170 180 190 200
SIKLEGKTHN WAVSKKLRES LEKPLILAGG LNKDNVLEAI KTVKPYAIDV
210 220
SSSLEAYGGK KDLKKVDEFL EVIKKV
Length:226
Mass (Da):25,306
Last modified:November 1, 1996 - v1
Checksum:i7B83DC1F16C5957E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98440.1.
PIRiC64356.
RefSeqiNP_247425.1. NC_000909.1.
WP_010869950.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98440; AAB98440; MJ_0451.
GeneIDi1451312.
KEGGimja:MJ_0451.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98440.1 .
PIRi C64356.
RefSeqi NP_247425.1. NC_000909.1.
WP_010869950.1. NC_000909.1.

3D structure databases

ProteinModelPortali Q57893.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243232.MJ0451.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB98440 ; AAB98440 ; MJ_0451 .
GeneIDi 1451312.
KEGGi mja:MJ_0451.

Phylogenomic databases

eggNOGi COG0135.
InParanoidi Q57893.
KOi K01817.
OMAi ETHDWER.
PhylomeDBi Q57893.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Entry informationi

Entry nameiTRPF_METJA
AccessioniPrimary (citable) accession number: Q57893
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3