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Q57886

- RIO1_METJA

UniProt

Q57886 - RIO1_METJA

Protein

RIO-type serine/threonine-protein kinase Rio1

Gene

rio1

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Nov 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei103 – 1031ATPPROSITE-ProRule annotation
    Active sitei214 – 2141Proton acceptorPROSITE-ProRule annotation
    Metal bindingi219 – 2191MagnesiumBy similarity
    Binding sitei219 – 2191ATPPROSITE-ProRule annotation
    Metal bindingi231 – 2311MagnesiumBy similarity
    Binding sitei231 – 2311ATPPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi82 – 909ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. protein serine/threonine kinase activity Source: UniProtKB-KW
    4. protein tyrosine kinase activity Source: InterPro

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RIO-type serine/threonine-protein kinase Rio1 (EC:2.7.11.1)
    Gene namesi
    Name:rio1
    Ordered Locus Names:MJ0444
    OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
    Taxonomic identifieri243232 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
    ProteomesiUP000000805: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 290290RIO-type serine/threonine-protein kinase Rio1PRO_0000213534Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243232.MJ0444.

    Structurei

    3D structure databases

    ProteinModelPortaliQ57886.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini76 – 290215Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG1718.
    KOiK07178.
    OMAiGDPRFHL.
    PhylomeDBiQ57886.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR018934. RIO-like_kinase.
    IPR000687. RIO_kinase.
    IPR018935. RIO_kinase_CS.
    IPR008266. Tyr_kinase_AS.
    [Graphical view]
    PfamiPF01163. RIO1. 1 hit.
    [Graphical view]
    SMARTiSM00090. RIO. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS01245. RIO1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q57886-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSCYKVMPIA KNIDDELYEL NKLLSEKEEF QLDREYQKEI LEKERKFLED    50
    LKTANEVFDK RTLMTLFSLL AGKHLTEYIG IVNSGKEAVV FKARKGKFYR 100
    AVKVYRVATC DFKTMSKYIQ GDPRFHLRKS SRRQIIHAWV EKEFRNLRRA 150
    SEIINAPKAR LRRENVLVMD FVGYRGIPAP KLKDMQDLDW EKYFKIIKES 200
    MKKLYEEGEL VHGDLSEYNI LVKDDEPVFI DFSQSVITQH PLAHPLLIRD 250
    CINICNFFRR KRVDCNYKDL YKYITGKEID PIDEAMIKQL 290
    Length:290
    Mass (Da):34,469
    Last modified:November 1, 1997 - v1
    Checksum:i52A8045266B2ACAB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98431.1.
    PIRiD64355.
    RefSeqiNP_247418.1. NC_000909.1.

    Genome annotation databases

    EnsemblBacteriaiAAB98431; AAB98431; MJ_0444.
    GeneIDi1451304.
    KEGGimja:MJ_0444.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98431.1 .
    PIRi D64355.
    RefSeqi NP_247418.1. NC_000909.1.

    3D structure databases

    ProteinModelPortali Q57886.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243232.MJ0444.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB98431 ; AAB98431 ; MJ_0444 .
    GeneIDi 1451304.
    KEGGi mja:MJ_0444.

    Phylogenomic databases

    eggNOGi COG1718.
    KOi K07178.
    OMAi GDPRFHL.
    PhylomeDBi Q57886.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR018934. RIO-like_kinase.
    IPR000687. RIO_kinase.
    IPR018935. RIO_kinase_CS.
    IPR008266. Tyr_kinase_AS.
    [Graphical view ]
    Pfami PF01163. RIO1. 1 hit.
    [Graphical view ]
    SMARTi SM00090. RIO. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS01245. RIO1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

    Entry informationi

    Entry nameiRIO1_METJA
    AccessioniPrimary (citable) accession number: Q57886
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Methanococcus jannaschii
      Methanococcus jannaschii: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3