Q57849 (Y406_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized sugar kinase MJ0406
EC=2.7.1.-

Gene names

Ordered Locus Names:

MJ0406

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the carbohydrate kinase pfkB family.

Ontologies

Keywords
Molecular function	Kinase Transferase
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	D-ribose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ribokinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 302

302

Uncharacterized sugar kinase MJ0406

PRO_0000080152

Secondary structure

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302

Helix Strand Turn

Details...

Beta strand

5 – 12

8

Beta strand

15 – 21

7

Beta strand

28 – 35

8

Beta strand

39 – 42

4

Helix

44 – 54

11

Beta strand

58 – 62

5

Turn

67 – 71

5

Helix

73 – 80

8

Beta strand

92 – 94

3

Beta strand

98 – 103

6

Beta strand

109 – 114

6

Helix

116 – 123

8

Beta strand

131 – 138

8

Helix

141 – 151

11

Beta strand

155 – 160

6

Helix

162 – 167

6

Helix

170 – 177

8

Beta strand

181 – 185

5

Helix

187 – 197

11

Helix

201 – 205

5

Beta strand

209 – 214

6

Helix

216 – 218

3

Beta strand

220 – 223

4

Beta strand

228 – 231

4

Helix

245 – 258

14

Helix

263 – 277

15

Beta strand

280 – 284

5

Helix

290 – 299

10

Sequences

	Sequence		Length	Mass (Da)
	Q57849 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 6A535606CC7D3260	FASTA	302	33,920
	10 20 30 40 50 60 MGGKMEKITC VGHTALDYIF NVEKFPEPNT SIQIPSARKY YGGAAANTAV GIKKLGVNSE 70 80 90 100 110 120 LLSCVGYDFK NSGYERYLKN LDINISKLYY SEEEETPKAW IFTDKDNNQI TFFLWGAAKH 130 140 150 160 170 180 YKELNPPNFN TEIVHIATGD PEFNLKCAKK AYGNNLVSFD PGQDLPQYSK EMLLEIIEHT 190 200 210 220 230 240 NFLFMNKHEF ERASNLLNFE IDDYLERVDA LIVTKGSKGS VIYTKDKKIE IPCIKAGKVI 250 260 270 280 290 300 DPTGAGDSYR AGFLSAYVKG YDLEKCGLIG AATASFVVEA KGCQTNLPTW DKVVERLEKH RI

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

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Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

L77117 Genomic DNA. Translation: AAB98396.1.

PIR

F64350.

RefSeq

NP_247380.1. NC_000909.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2C49	X-ray	1.92	A/B	1-302	[»]
2C4E	X-ray	1.70	A	1-302	[»]

ProteinModelPortal

Q57849.

SMR

Q57849. Positions 3-301.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1451266.

GenomeReviews

Gene locus MJ0406 in contig L77117_GR.

KEGG

mja:MJ_0406.

NMPDR

fig|243232.1.peg.417.

TIGR

MJ0406.

Phylogenomic databases

HOGENOM

HBG539057.

OMA

ITAVGHI.

ProtClustDB

CLSK876173.

Enzyme and pathway databases

BioCyc

MJAN243232:MJ_0406-MONOMER.

Family and domain databases

InterPro

IPR011611. Carb/pur_kinase.
IPR002173. Carboh/pur_kinase_PfkB_CS.
IPR002139. Ribokinase.
[Graphical view]

Pfam

PF00294. PfkB. 1 hit.
[Graphical view]

PRINTS

PR00990. RIBOKINASE.

PROSITE

PS00583. PFKB_KINASES_1. 1 hit.
PS00584. PFKB_KINASES_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Y406_METJA

Accession

Primary (citable) accession number: Q57849

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	October 19, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program