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Protein

DNA-directed RNA polymerase subunit E'

Gene

rpoE1

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit E' (EC:2.7.7.6)
Gene namesi
Name:rpoE1
Ordered Locus Names:MJ0397
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000740361 – 187DNA-directed RNA polymerase subunit E'Add BLAST187

Interactioni

Protein-protein interaction databases

IntActiQ57840. 1 interactor.
STRINGi243232.MJ_0397.

Structurei

Secondary structure

1187
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 13Combined sources12
Helixi15 – 17Combined sources3
Helixi22 – 34Combined sources13
Turni40 – 42Combined sources3
Beta strandi43 – 54Combined sources12
Beta strandi65 – 77Combined sources13
Beta strandi84 – 93Combined sources10
Beta strandi96 – 100Combined sources5
Beta strandi102 – 109Combined sources8
Helixi110 – 112Combined sources3
Beta strandi118 – 120Combined sources3
Beta strandi127 – 129Combined sources3
Turni130 – 132Combined sources3
Beta strandi141 – 150Combined sources10
Beta strandi160 – 164Combined sources5
Helixi173 – 183Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GO3X-ray1.75E/M1-187[»]
ProteinModelPortaliQ57840.
SMRiQ57840.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ57840.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini82 – 166S1 motifPROSITE-ProRule annotationAdd BLAST85

Sequence similaritiesi

Contains 1 S1 motif domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiarCOG00675. Archaea.
COG1095. LUCA.
InParanoidiQ57840.
KOiK03049.
OMAiRIPPRMF.
PhylomeDBiQ57840.

Family and domain databases

Gene3Di3.30.1490.120. 1 hit.
InterProiIPR012340. NA-bd_OB-fold.
IPR005576. RNA_pol_Rpb7_N.
IPR004519. RNAP_E/RPC8.
IPR022967. S1_dom.
IPR003029. S1_domain.
[Graphical view]
PfamiPF00575. S1. 1 hit.
PF03876. SHS2_Rpb7-N. 1 hit.
[Graphical view]
SMARTiSM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF88798. SSF88798. 1 hit.
TIGRFAMsiTIGR00448. rpoE. 1 hit.
PROSITEiPS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q57840-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKILEIADV VKVPPEEFGK DLKETVKKIL MEKYEGRLDK DVGFVLSIVD
60 70 80 90 100
VKDIGEGKVV HGDGSAYHPV VFETLVYIPE MYELIEGEVV DVVEFGSFVR
110 120 130 140 150
LGPLDGLIHV SQIMDDYVSY DPKREAIIGK ETGKVLEIGD YVRARIVAIS
160 170 180
LKAERKRGSK IALTMRQPYL GKLEWIEEEK AKKQNQE
Length:187
Mass (Da):21,216
Last modified:November 1, 1997 - v1
Checksum:iC0E4EA3C006D69DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98387.1.
PIRiE64349.
RefSeqiWP_010869896.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98387; AAB98387; MJ_0397.
GeneIDi1451254.
KEGGimja:MJ_0397.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98387.1.
PIRiE64349.
RefSeqiWP_010869896.1. NC_000909.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GO3X-ray1.75E/M1-187[»]
ProteinModelPortaliQ57840.
SMRiQ57840.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ57840. 1 interactor.
STRINGi243232.MJ_0397.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB98387; AAB98387; MJ_0397.
GeneIDi1451254.
KEGGimja:MJ_0397.

Phylogenomic databases

eggNOGiarCOG00675. Archaea.
COG1095. LUCA.
InParanoidiQ57840.
KOiK03049.
OMAiRIPPRMF.
PhylomeDBiQ57840.

Miscellaneous databases

EvolutionaryTraceiQ57840.

Family and domain databases

Gene3Di3.30.1490.120. 1 hit.
InterProiIPR012340. NA-bd_OB-fold.
IPR005576. RNA_pol_Rpb7_N.
IPR004519. RNAP_E/RPC8.
IPR022967. S1_dom.
IPR003029. S1_domain.
[Graphical view]
PfamiPF00575. S1. 1 hit.
PF03876. SHS2_Rpb7-N. 1 hit.
[Graphical view]
SMARTiSM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF88798. SSF88798. 1 hit.
TIGRFAMsiTIGR00448. rpoE. 1 hit.
PROSITEiPS50126. S1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPOE1_METJA
AccessioniPrimary (citable) accession number: Q57840
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.