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Protein

DNA-directed RNA polymerase subunit E'

Gene

rpoE1

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processTranscription

Enzyme and pathway databases

BioCyciMJAN243232:G1GKE-424-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit E' (EC:2.7.7.6)
Gene namesi
Name:rpoE1
Ordered Locus Names:MJ0397
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000740361 – 187DNA-directed RNA polymerase subunit E'Add BLAST187

Interactioni

Protein-protein interaction databases

IntActiQ57840, 1 interactor
STRINGi243232.MJ_0397

Structurei

Secondary structure

1187
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 13Combined sources12
Helixi15 – 17Combined sources3
Helixi22 – 34Combined sources13
Turni40 – 42Combined sources3
Beta strandi43 – 54Combined sources12
Beta strandi65 – 77Combined sources13
Beta strandi84 – 93Combined sources10
Beta strandi96 – 100Combined sources5
Beta strandi102 – 109Combined sources8
Helixi110 – 112Combined sources3
Beta strandi118 – 120Combined sources3
Beta strandi127 – 129Combined sources3
Turni130 – 132Combined sources3
Beta strandi141 – 150Combined sources10
Beta strandi160 – 164Combined sources5
Helixi173 – 183Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GO3X-ray1.75E/M1-187[»]
ProteinModelPortaliQ57840
SMRiQ57840
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ57840

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini82 – 166S1 motifPROSITE-ProRule annotationAdd BLAST85

Phylogenomic databases

eggNOGiarCOG00675 Archaea
COG1095 LUCA
InParanoidiQ57840
KOiK03049
OMAiMRQPGLG
OrthoDBiPOG093Z0C8D
PhylomeDBiQ57840

Family and domain databases

Gene3Di3.30.1490.120, 1 hit
InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR036898 RNA_pol_Rpb7-like_N_sf
IPR005576 RNA_pol_Rpb7_N
IPR004519 RNAP_E/RPC8
IPR022967 S1_dom
IPR003029 S1_domain
PfamiView protein in Pfam
PF00575 S1, 1 hit
PF03876 SHS2_Rpb7-N, 1 hit
SMARTiView protein in SMART
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF88798 SSF88798, 1 hit
TIGRFAMsiTIGR00448 rpoE, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

Q57840-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKILEIADV VKVPPEEFGK DLKETVKKIL MEKYEGRLDK DVGFVLSIVD
60 70 80 90 100
VKDIGEGKVV HGDGSAYHPV VFETLVYIPE MYELIEGEVV DVVEFGSFVR
110 120 130 140 150
LGPLDGLIHV SQIMDDYVSY DPKREAIIGK ETGKVLEIGD YVRARIVAIS
160 170 180
LKAERKRGSK IALTMRQPYL GKLEWIEEEK AKKQNQE
Length:187
Mass (Da):21,216
Last modified:November 1, 1997 - v1
Checksum:iC0E4EA3C006D69DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA Translation: AAB98387.1
PIRiE64349
RefSeqiWP_010869896.1, NC_000909.1

Genome annotation databases

EnsemblBacteriaiAAB98387; AAB98387; MJ_0397
GeneIDi1451254
KEGGimja:MJ_0397

Similar proteinsi

Entry informationi

Entry nameiRPOE1_METJA
AccessioniPrimary (citable) accession number: Q57840
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health