Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein translocase subunit SecE

Gene

secE

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecEUniRule annotation
Alternative name(s):
Protein transport protein Sec61 gamma subunit homologUniRule annotation
Gene namesi
Name:secEUniRule annotation
Ordered Locus Names:MJ0371
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 36CytoplasmicAdd BLAST36
Transmembranei37 – 62HelicalAdd BLAST26
Topological domaini63 – 74ExtracellularAdd BLAST12

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001042191 – 74Protein translocase subunit SecEAdd BLAST74

Interactioni

Subunit structurei

Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.1 Publication

Protein-protein interaction databases

IntActiQ57817. 2 interactors.
MINTiMINT-8378567.
STRINGi243232.MJ_0371.

Structurei

Secondary structure

174
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi14 – 24Combined sources11
Beta strandi25 – 27Combined sources3
Helixi31 – 66Combined sources36

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1RH5X-ray3.20B1-74[»]
1RHZX-ray3.50B1-74[»]
2YXQX-ray3.50B1-74[»]
2YXRX-ray3.60B1-74[»]
3BO0electron microscopy9.60B28-67[»]
3BO1electron microscopy9.60B28-67[»]
3DKNelectron microscopy8.70B3-67[»]
4V4Nelectron microscopy9.00A71-67[»]
4V7Ielectron microscopy-B28-67[»]
ProteinModelPortaliQ57817.
SMRiQ57817.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ57817.

Family & Domainsi

Sequence similaritiesi

Belongs to the SecE/SEC61-gamma family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiarCOG02204. Archaea.
COG2443. LUCA.
InParanoidiQ57817.
KOiK07342.
OMAiVLMISRK.

Family and domain databases

Gene3Di1.20.5.820. 1 hit.
HAMAPiMF_00422. SecE. 1 hit.
InterProiIPR023391. Prot_translocase_SecE_dom.
IPR022943. SecE.
IPR008158. Translocase_Sec61-g.
[Graphical view]
SUPFAMiSSF103456. SSF103456. 1 hit.
TIGRFAMsiTIGR00327. secE_euk_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

Q57817-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTDFNQKIE QLKEFIEECR RVWLVLKKPT KDEYLAVAKV TALGISLLGI
60 70
IGYIIHVPAT YIKGILKPPT TPRV
Length:74
Mass (Da):8,438
Last modified:November 1, 1996 - v1
Checksum:i10474AE938CC0ECD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98360.1.
PIRiC64346.
RefSeqiWP_010869870.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98360; AAB98360; MJ_0371.
GeneIDi1451228.
KEGGimja:MJ_0371.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98360.1.
PIRiC64346.
RefSeqiWP_010869870.1. NC_000909.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1RH5X-ray3.20B1-74[»]
1RHZX-ray3.50B1-74[»]
2YXQX-ray3.50B1-74[»]
2YXRX-ray3.60B1-74[»]
3BO0electron microscopy9.60B28-67[»]
3BO1electron microscopy9.60B28-67[»]
3DKNelectron microscopy8.70B3-67[»]
4V4Nelectron microscopy9.00A71-67[»]
4V7Ielectron microscopy-B28-67[»]
ProteinModelPortaliQ57817.
SMRiQ57817.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ57817. 2 interactors.
MINTiMINT-8378567.
STRINGi243232.MJ_0371.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB98360; AAB98360; MJ_0371.
GeneIDi1451228.
KEGGimja:MJ_0371.

Phylogenomic databases

eggNOGiarCOG02204. Archaea.
COG2443. LUCA.
InParanoidiQ57817.
KOiK07342.
OMAiVLMISRK.

Miscellaneous databases

EvolutionaryTraceiQ57817.

Family and domain databases

Gene3Di1.20.5.820. 1 hit.
HAMAPiMF_00422. SecE. 1 hit.
InterProiIPR023391. Prot_translocase_SecE_dom.
IPR022943. SecE.
IPR008158. Translocase_Sec61-g.
[Graphical view]
SUPFAMiSSF103456. SSF103456. 1 hit.
TIGRFAMsiTIGR00327. secE_euk_arch. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSECE_METJA
AccessioniPrimary (citable) accession number: Q57817
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.